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ECG-derived spatial QRS-T angle is strongly associated with hypertrophic cardiomyopathy

Introduction: ECG-derived vectorcardiography (VCG) has diagnostic and prognostic value in various diseases. Hypertrophic cardiomyopathy (HCM), a genetic disease with unexplained left ventricular hypertrophy, is one of the most common causes of sudden cardiac death (SCD) in young persons. Genotype positive status is associated with increased risk of systolic dysfunction, heart failure, and (SCD). H

The sensitivity of ginkgo leaf unfolding to the temperature and photoperiod decreases with increasing elevation

Climate change substantially affects plant phenology, resulting in earlier vegetation onset across temperate and boreal regions. Phenological shifts caused by warming may alter species interactions across trophic levels because of species-specific responses, and influence the reproductive success of dioecious species if the phenological sensitivity to warming (ST) differs between genders. We used

Optimal Pressure Management in Water Distribution Systems : Efficiency Indexes for Volumetric Cost Performance, Consumption and Linear Leakage Measurements

Water is a finite resource and should be given the attention it deserves to reduce its depletion through leakages in pipe systems. The authors implemented pressure management strategies linked to fixed and variable discharge (FAVAD), the burst and background estimate (BABE), and orifice principle methodologies to analyze a two-phased comparative method for applying optimal pressure management and

The positive net radiative greenhouse gas forcing of increasing methane emissions from a thawing boreal forest‐wetland landscape

At the southern margin of permafrost in North America, climate change causes widespread permafrost thaw. In boreal lowlands, thawing forested permafrost peat plateaus (‘forest’) lead to expansion of permafrost‐free wetlands (‘wetland’). Expanding wetland area with saturated and warmer organic soils is expected to increase landscape methane (CH4) emissions. Here, we quantify the thaw‐induced increa

Usefulness of a clinical risk score to predict the response to cardiac resynchronization therapy

Background: Almost 1/3 of heart failure patients fail to respond to cardiac resynchronization therapy (CRT). A simple clinical score to predict who these patients are at the moment of referral or at time of implant may be of importance for early optimization of their management. Methods: Observational study. A risk score was derived from factors associated to CRT response. The derivation cohort wa

Comparing three methods for lipid identification using mass spectrometry - Data-independent, data-dependent and targeted acquisition

Introduction: This study evaluated lipid identification using mass spectrometry. Background: Three main modes of acquisition are used in mass spectrometry of lipids; data-independent acquisition (DIA), data-dependent acquisition (DDA) and targeted acquisition. DIA is the most including one, yielding a complete but complex data set, while targeted is the least including one, basing acquisition on

Skydd för visselblåsare – ett komplext område. Om det rättsliga skyddet för arbetstagare som slår larm om missförhållanden på arbetsplatsen

Syftet med denna uppsats är att granska det rättsliga skyddet för visselblåsare i Sverige. Syftet är även att utreda om eventuella problem som finns med detta skydd löses genom de lagförslag som finns i de offentliga utredningarna SOU 2013:79 och SOU 2014:31. Det finns inte någon lagstiftning i Sverige som specifikt inriktar sig på skydd för visselblåsare. Det rättsliga skyddet är komplext och berThe purpose of this paper is to examine the legal protection of whistleblowers in Sweden. The purpose is also to examine if any problems with this legal protection are solved by the bills in two Government Official Reports – SOU 2013:79 and SOU 2014:31. There is no specific regulation in Swedish law for the protection of whistleblowers. The legal protection is complex and different rules from diff

Getting Wealthier and Healthier? Evidence From the Spanish Christmas Lottery

This paper uses the Spanish Christmas Lottery to provide new evidence about the relationship between wealth and health for adults and infants. Using a difference-in-difference design across provinces and time, I explore how overall health status, hospitalization rates, neonatal health, and alcohol consumption are affected by lottery outcomes. For adults, my results suggest no immediate effect on t

The Potential to Target Smaller Sized Baltic Herring to Decrease the Dietary Exposure - an Assessment Based on Dioxin Samples from the Southern Baltic

PCDD/Fs and dl-PCBs, or more commonly referred to as dioxin and dioxin like substances are compounds present in our surrounding environment. As some congeners of these have been shown to be toxic, they are regulated under the Stockholm Convention. As dioxins are persistent in biota and have lipophilic properties they are seen accumulating in lipid rich fish in the Baltic, one of the affected speci

The polarized attitudes of offshore wind - The social acceptance of planned offshore wind farm Västvind among Öckerö municipality residents

Klimatförändringarna, energikrisen och en ökande efterfrågan på el har uppmärksammat behovet av en hållbar omställning av energisystemet. Havsbaserad vindkraft spelar en viktig roll i denna omställning och förväntas expandera kraftigt globalt, i EU och i Sverige. Samtidigt möter projekt stort lokalt motstånd. Trots att svenskar generellt visar högt stöd för vindkraft så har en majoritet av de senaClimate change, the energy crisis of 2022-2023, and estimations of future electricity demands have stressed the necessity for a rapid transition of the energy system. Offshore wind energy plays an important role in this transition, and is expected to expand considerably on a global level, in the EU and in Sweden. While Swedes show high support of wind energy, a majority of recent projects have bee

Kommunernas planmonopol - En studie av fem skånska kommuner med bostadsbrist

År 2020 anger 212 av 286 kommuner i Sverige att de har ett underskott på bostäder i kommunen som helhet. Sveriges befolkning ökar och bostadsbeståndet hänger inte med. I studien syftar bostadsbristen till definitionen som är skillnaden mellan vad som kollektivt uppfattas som en godtagbar bostadssituation och det faktiska läget på marknaden. Situationer som inte kollektivt anses vara godtagbara bosThe housing responsibility in Sweden is primarily controlled by the municipalities. The municipalities in Sweden have a monopoly on controlling land use with detailed development plans. The population rises every day and the majority of the Swedish municipalities confirms having lack of housing. This study has been made in order to investigate how five municipalities work with their housing respon

Emergency Power for Wind Turbine Yaw System - Project initialization tool

The Yaw Power Backup System (YPBS) is a safety system that needs to be incorporated in the Wind Power Plant (WPP) in order to provide emergency power during a power outage. The YPBS enables the Wind Turbine Generator (WTG) to perform a yawing operation in extreme weather conditions. The yawing operation ensures the rotor is aligned with incoming wind, minimizing the acting forces on the blades and

Structural analysis of X-flo measure system

This thesis is done in cooperation with Dresser Wayne AB in Malmö and the objective has been to investigate if it is possible to use the X-flo meter, see Figure 1, in an LPG-dispencer. An increased pressure is used in the LPG-system, which involves a higher risk of leaking and strength problems. During the development consideration has been taken to a new outlet, though other couplings are used in

Framtagning av model, för små frö till precisionssåmaskin

This thesis project was to develop a module for a forest precision seeder. The project is made at BCC AB. BCC is a worldwide supplier of forest seed centre and containerized nursery equipment. BCC develops, designs, produces and sales machines for forest seed handling. BCC s existing precision seeder can not handle seed that are tinier than 1 mm in diameter. With a growing market in countries with

Too sick to fly. Immune response activation prolongs stopover duration of migrating passerines

Most migratory bird species divide their migration in stages of flight and stopovers. They use these stopovers to refuel the energy reserves needed to face their long migration journeys. These stopovers are an important element to determine the overall migration speed. Time spent on migration and arrival date to the wintering grounds have been demonstrated to have a large effects the following bre

Synthesis and characterization of amine-functionalized microgel particles and their subsequent assembly into colloidal molecule-like clusters by droplet-based microfluidics

Kolloider är partiklar i storleksordningen nm till μm. De är viktiga i biologiska system, där exempelvis proteiner är en typ av kolloid. Att studera kolloider ger oss därför insikt i hur till exempel proteiner byggs upp och interagerar. I detta fall försökte vi tillverka kolloidala molekyler, alltså kolloider som interagerar med varandra genom ett specifikt antal bindningar i väl definierade positThe ability of thermoresponsive, amine-functionalized microgel particles to take part in microgelmicrogel inter-cross-linking has previously been reported in the literature, in connection to applications such as for example the formation of stimuli-responsive colloidal gels and colloidosomes [1]. This thesis deals with the synthesis of such thermoresponsive, cross-linkable microgels and their subs

Triglyceride-glucose (TyG) index is a predictor of arterial stiffness, incidence of diabetes, cardiovascular disease, and all-cause and cardiovascular mortality: A longitudinal two-cohort analysis

BACKGROUND: Triglyceride-glucose (TyG) index is a useful low-cost marker of insulin resistance. We aimed to evaluate the association between TyG index and arterial stiffness, incidence of diabetes, adverse cardiovascular outcomes, and all-cause and cardiovascular mortality in two large prospective Swedish cohorts, the Malmö Diet and Cancer Study-Cardiovascular Cohort (MDCS-CV) and the Malmö Preven

Prognostic and predictive performance of R-ISS with SKY92 in older patients with multiple myeloma : The HOVON-87/NMSG-18 trial

The standard prognostic marker for multiple myeloma (MM) patients is the revised International Staging System (R-ISS). However, there is room for improvement in guiding treatment. This applies particularly to older patients, in whom the benefit/risk ratio is reduced because of comorbidities and subsequent side effects. We hypothesized that adding gene-expression data to R-ISS would generate a stro

The impact of chronic widespread pain on health status and long-term health predictors : A general population cohort study

Background: Chronic widespread pain (CWP) has a negative impact on health status, but results have varied regarding gender-related differences and reported health status. The aim was to study the impact of CWP on health status in women and men aged 35-54 years in a sample of the general population. The aim was further to investigate lifestyle-related predictors of better health status in those wit