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Background and objective: Human studies of arterio-venous (AV) differences in drug concentrations and the consequences for pharmacokinetic modelling and concentration-effect relationships are very limited. We therefore investigated the intravenous and intra-arterial concentrations of alcohol (ethanol) during the absorption, distribution and elimination stages of alcohol metabolism in healthy men.

Solitary bees and bumblebees have declined substantially throughout western Europe during the last 100 years. Many species are important pollinators and are associated with particular plant species and habitats. In this study we report the highest number of bee species found at one locality in Sweden (Table 2). In total 87 species of wild bees (74 species of solitary bees and 13 species of bumble

Cross-sectional studies have associated obesity and other components of the so-called metabolic syndrome with low-grade inflammation. The temporal and causal relations of this association have not been fully explored. This study explored whether elevated levels of inflammation-sensitive plasma proteins (ISPs) (fibrinogen, orosomucoid, {alpha}1-antitrypsin, haptoglobin, and ceruloplasmin) are assoc

Abstract is not available

Embedded systems are a characteristic but intangible part of an embedding environment. This poses a severe testing problem that gets further aggravated in embedded networks. The co-presence of hardware and software needs both behavioral and structural aspects to be covered, preferably by a single on-chip paradigm. The paper investigates the potential role of neural networks and introduces a Built-

This study considers detection of polyproline type II secondary structures from protein sequences. This difficult problem was handled with multilayer perceptron neural networks, which were found to be useful for such bioinformatics studies. Polyproline II secondary structures have not previously been tried to be predicted from sequences.

High-profile bribery scandals that involve powerful people and large sums of money are often the object of general indignation and legal action. When it comes to bribery of the everyday kind, however, it is far less obvious which gifts should be seen as bribes, be it in a moral or legal sense. Legal cases of this kind almost always include voices that strive to refute accusations of bribery. This

The use of this material under current use conditions is supported by the existing information. This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization potential as well as environmental safety. Repeated dose, developmental, and reproductive toxicities were determined to have

The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Repeated Dose Toxicity was determined to have the most conservative systemic e

The gain profile of a quantum cascade laser is strongly influenced by the lifetime of the carriers in the upper and lower laser state. The quantitative description of gain within the concept of nonequilibrium Green's functions allows for a detailed understanding of various features affecting the gain spectrum: Compensation effects between scattering processes in the upper and lower laser level, re

Analysis of the system of criminal procedure in Sweden in light of the proposal for the establishment of a European Public Prosecutor's Office.

Strength grading of Norway spruce side boards in the wet state was investigated. For a sample of 58 boards of dimensions 25×120×3000 mm3, density and dynamic modulus of elasticity in the axial direction, MOEdyn, were determined in the wet state. The boards were then split into two parts and the procedure of determining MOEdyn was repeated both before and after the boards were dried to a target

The use of this material under current use conditions is supported by the existing information. This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization potential as well as environmental assessment. Repeated Dose Toxicity was determined to have the most conservative systemic e

Abstract in UndeterminedThe capacity of shrub canopy water storage is a key factor in controlling the rainfall interception. Thus, it affects a variety of hydrological processes in water-limited arid desert ecosystems. Vast areas of revegetated desert ecosystems in Northwestern China are occupied by shrub and dwarf shrub communities. Yet, data are still scarce regarding their rainwater storage cap

The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Reproductive toxicity was based on the Threshold of Toxicological Concern (TTC