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A method to find the optimum routes and stations for Bus Rapid Transit in urban areas

Public transportation (PT) is an essential system for cities to achieve sustainability. However, determination of proper locations for PT stations and finding suitable routes are critical decisions. This paper aims to propose a novel method to determine BRT stations and routes in the cities, using Fuzzy Inference System (FIS) and Binary Integer Programming (BIP). In the proposed method, first, a s

Language and Its Limits : Meaning, Reference and the Ineffable in Buddhist Philosophy

Buddhist schools of thought share two fundamental assumptions about language. On the one hand, language (śabda) is identified with conceptual thinking (kalpanā), which according to the Buddhist doctrine (dharma) separates us from the momentary and fleeting nature of reality (satya, “truth”). Language is comprised of generally applicable forms, which fuel the reificatory proclivity for clinging to

Swedish primary care physicians’ intentions to use telemedicine : A survey using a new questionnaire – physician attitudes and intentions to use telemedicine (pait)

Background: Research on intentions to use telemedicine in primary care is sparse. This survey study explored primary care physicians’ intentions to use telemedicine by using a newly developed questionnaire: Physician Attitudes and Intentions to use Telemedicine. Methods: An anonymous web-survey with questions focusing on theory-based predictors of behavioral intentions such as Attitudes, Subjectiv

Review Topography of Sound Art

Austrian artist and director of ZKM Center for Art and Media in Karlsruhe, Germany, Peter Weibel (Odessa, 1944), curates a book/catalogue of the mythical exhibition Sound Art, Sound as Medium of Art, that took place between March 2012 and February 2013 in Karlsruhe, with nearly one thousand images of sound art pieces. Along with a very detailed historical trace of sound as a form of art, the book

Synthetic Life and the Value of Life

If humans eventually attain the ability to create new life forms, how will it affect the value of life? This is one of several questions that can be sources of concern when discussing synthetic life, but is the concern justified? In an attempt to answer this question, I have analyzed some possible reasons why an ability to create synthetic life would threaten the value of life in general (that is,

“True Religion” and Hume’s Practical Atheism

The argument and discussion in this paper begins from the premise that Hume was an atheist who denied the religious or theist hypothesis. However, even if it is agreed that that Hume was an atheist this does not tell us where he stood on the question concerning the value of religion. Some atheists, such as Spinoza, have argued that society needs to maintain and preserve a form of “true religion”,

Thirteenth-Century Aristotelian Logic : The Study of Scientific Method

The aims of this paper are to show (i) that thirteenth-century Aristotelian logic (AL-13) is a logical tradition that considers Aristotelian logic (AL: the logical curriculum at the University of Paris, that is, Porphyry’s Isagoge, Aristotle’s Organon, Boethius’s De divisione and De topicis differentiis, and the anonymous Sex principia) as a system that is organized around the syllogistic argument

Towards a Socio-Legal Robotics: A Theoretical Framework on Norms and Adaptive Technologies

While recent progress has been made in several fields of data-intense AI-research, many applications have been shown to be prone to unintendedly reproduce social biases, sexism and stereotyping, including but not exclusive to gender. As more of these design-based, algorithmic or machine learning methodologies, here called adaptive technologies, become embedded in robotics, we see a need for a deve

Realism and idealism in Rāmānuja’s self-body metaphor

The ontology of Rāmānuja, as expressed in his Gītābhāṣya and other works, centres on the doctrine of coordinate predication (sāmānādhikaraṇya), expressed through the metaphor of the self-body relationship (ātma-śarīra-bhāva). This metaphor, employed to define the ontological status of God (Nārāyaṇa), the individual selves and the world, also serves as a strategy for reconciling apparently conflict

Return to work: One and two years follow-up after interdisciplinary pain rehabilitation. A study based on the Swedish Quality Registry for Pain Rehabilitation

Objectives: To investigate: (i) changes in sick-leave benefits from 1 year prior to multimodal rehabilitation to 1 and 2 years after rehabilitation; (ii) sex differences in sick leave; and (iii) the impact of policy changes on sick leave. Methods: All patients undergoing multimodal rehabilitation registered in a national pain database for 2007–11 (n?=?7,297) were linked to the Swedish Social I

Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)

Background: Self-reported smoking is the principal measure used to assess lung cancer risk in epidemiological studies. We evaluated if circulating cotinine-a nicotine metabolite and biomarker of recent tobacco exposure-provides additional information on lung cancer risk. Methods: The study was conducted in the Lung Cancer Cohort Consortium (LC3) involving 20 prospective cohort studies. Pre-diagnos

Numerical study on saltwater intrusion in a heterogeneous stratified aquifer

In a costal aquifer, saltwater intrusion is frequently observed due to an excess exploitation. There are many researches focused on the saltwater intrusion. However, there are few researches, which take into consideration the mixing processes in a stratified heterogeneous aquifer. In the present study, a laboratory experiment and numerical simulation are made in order to understand the phenomena i

On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations

The aggregation of the amyloid-β (Aβ) peptide is linked to the pathogenesis of Alzheimer’s disease (AD). In particular, some point mutations within Aβ are associated with early-onset familial Alzheimer’s disease. Here we set out to explore how the physical properties of the altered side chains, including their sizes and charges, affect the molecular mechanisms of aggregation. We focus on Aβ42 with

Influence of left atrial size on P-wave morphology : differential effects of dilation and hypertrophy

Aims: Chronic left atrial enlargement (LAE) increases the risk of atrial fibrillation. Electrocardiogram (ECG) criteria might provide a means to diagnose LAE and identify patients at risk; however, current criteria perform poorly. We seek to characterize the potentially differential effects of atrial dilation vs. hypertrophy on the ECG P-wave. Methods and results: We predict effects on the P-wave