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Fundamental Social Rights and the EU Charter in Times of Crisis : Reality and Prospects

The core aim of this chapter is to explore the potential of the EU Charter in developing social protection in times of poly-crisis. In the past, EU Member States have gone through a number of events that have been termed as crises, calling for a paradigm shift in EU governance (economic, migration, and more recently health crises). While the effects of these crises are still felt, the EU is faced

Tailored Dose-Dense Versus Standard Adjuvant Chemotherapy for High-Risk Early Breast Cancer: End-of-Study Results of the Randomized PANTHER Trial

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has

Spectator Matter in Collisions of Relativistic Deformed Nuclei

Abstract: The Abrasion–Ablation Monte Carlo for Colliders (AAMCC) model is used to study the characteristics of spectator matter in central collisions of relativistic 238U nuclei, which are sensitive to the mutual orientation and the degree of deformation of the colliding nuclei. It is shown that the multiplicity of spectator neutrons and their forward-backward asymmetry substantially depend on th

OS03-11 Exposure to PFAS and associated toxicity in workers exposed to hexavalent chromium – a cross-sectional study within the SafeChrom project : Abstracts of the 58th Congress of the European Societies of Toxicology (EUROTOX 2024)

BackgroundThis study aimed to investigate the exposure to perfluoroalkyl substances (PFAS) and cancer-related toxicity in workers in different Swedish industry sectors with exposures to hexavalent chromium (Cr(VI)).MethodsThe study consisted of 111 exposed workers and 72 controls. The exposed workers were performing manufacture/processing of metal products (n=55), working in steel production (n=31

Analysis of the Horometer Instrument in Peter Apian's Instrument Buch

The Horometer instrument in Peter Apian's 1533 Instrument Buch is described and analyzed. This paper is illustrated by several examples of how to manipulate and set up the instrument using the Sun, the Moon and stars to determine time. The paper also contains an Appendix on the mathematics behind its construction.

The Experience of Emergency Department Providers With Embedded Palliative Care During COVID

CONTEXT: Although the importance of palliative care (PC) integration in the emergency department (ED) has long been recognized, few formalized programs have been reported, and none have evaluated the experience of ED clinicians with embedded PC.OBJECTIVES: We evaluate the experience of ED clinicians with embedded PC in the ED during the coronavirus disease pandemic.METHODS: ED clinicians completed

Characterizing the allele-specific gene expression landscape in high hyperdiploid acute lymphoblastic leukemia with BASE

Somatic copy number variations (CNVs), including abnormal chromosome numbers and structural changes leading to gain or loss of genetic material, play a crucial role in initiation and progression of cancer. CNVs are believed to cause gene dosage imbalances and modify cis-regulatory elements, leading to allelic expression imbalances in genes that influence cell division and thereby contribute to can

Translating transitions - How to decipher peripheral human B cell development

During the last two decades our understanding of human B cell differentiation has developed considerably. Our understanding of the human B cell compartment has advanced from a point where essentially all assays were based on the presence or not of class-switched antibodies to a level where a substantial diversity is appreciated among the cells involved. Several consecutive transitional stages that

The artful early instruments of Peter Apianus : Ein kunstlich Instrument of 1524, its precursors and its successors

In 1524, Petrus Apianus published two closely related works—one the Latin Cosmographicus liber, aimed at an educated audience of international readers, and the other, Ein kunstlich Instrument, a shorter, more practical book for those who could read German but had no Latin. Both books nevertheless make use of most of the same instruments, including Apianus’ early volvelles. Most of these instrument

Physicians’ intentions to use digital tools–a comparative survey, before and after the COVID-19 pandemic, in Southern Sweden

Objectives: To describe changes in Swedish primary care physicians’ use of, attitudes and intentions toward digital tools in patient care between 2019 and 2022. Design: A survey using a validated questionnaire measuring physician’s intentions to use digital tools based on the theory of planned behavior. Setting: Sample of primary health care centers in southern Sweden. Subjects: Primary care physi

Intracranial Atherosclerosis in Medieval Scandinavia

In past human populations, atherosclerosis has been identified in mummies from different regions of the world, and from a range of chronological periods (for extensive reviews see Chapters 3 and 4). This current study from Sweden aims to contribute to the limited evidence for atherosclerosis associated with human skeletal remains by presenting examples of atherosclerosis in another part of the bod

Factors affecting the long-term prognosis of patients in the AYA generation with epithelial ovarian cancer : A multicenter propensity score matching analysis

Objective: Ovarian carcinoma (OvCa) is more common in the elderly, but also affects the adolescent and young adult (AYA) generation, which refers to those aged 15–39 years. Although the characteristics of OvCa may differ between AYAs and non-AYAs, limited information is currently available on differences in prognostic factors. Therefore, we herein investigated prognostic factors for and the progno

New Book in the Bag to Berlin : Review of John Kampfner: In Search of Berlin: The Story of a Reinvented City

Berlin is a major tourist destination, a world city with a dramatic history. Many shelf meters have been written about it, not least combinations of travel guide and history book. The latest contribution of this kind is John Kampfner’s in Search of Berlin: The Story of a Reinvented City (London: Atlantic Books 2023, 400 pages). Kampfner is a British author, journalist and documentary maker with a

PET-CT imaging of neuroendocrine tumours - Beyond diagnostics

Background: Neuroendocrine tumours (NETs) typically overexpress somatostatin receptors. By radiolabelling somatostatin analogues with a positron-emitting radionuclide (68Ga-DOTATOC or 68Ga-DOTATATE), these tumours can be detected with high sensitivity and specificity using somatostatin receptor positron emission tomography-computed tomography (PET-CT).Aim: To enhance knowledge about NETs imaged wi

Effect of fiber curvature on gas diffusion layer two-phase dynamics of proton exchange membrane fuel cells

Both straight and curved carbon fibers are widely used in various commercial gas diffusion layer (GDL) fabrications. The effect of the different carbon fiber curvatures on two-phase flow dynamics within the cathode GDLs of proton exchange membrane fuel cells remains unclear. In this study, we investigate liquid transport in three types of GDLs with varying fiber curvatures using the two-phase volu

Everyday nuclear histories and futures in the Middle East, 1945–1948

This article examines nuclear imaginaries in the Arabic-speaking Middle East. It situates people from the Arab world into nuclear thought, looking at how the atomic age rapidly became part of everyday lives. Embracing the idea that reality and fiction are not only deeply intertwined but also co-constitutive, it analyses everyday engagements with the nuclear condition in the aftermath of the bombin