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PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents

Aims: Survival after cancer diagnosed during childhood or adolescence continues to improve with new treatments and supportive therapies. Optimal long-term care requires that risks to vulnerable organs are clearly defined and translated into guidelines that are implemented into practice. PanCareLIFE is a pan-European consortium that addresses survivorship issues comprising fertility, hearing impair

In Vivo Effects of Phytic Acid and Polyphenols on the Bioavailability of Polysaccharides and Other Nutrients

The effects of the antinutrients tannic acid, catechin and phytic acid on digestion of starch, protein and lipids, and fiber degradation were studied in rat balance experiments. To separate digestion in the small intestine from fermentation in the hind‐gut, diets were tested without and with the addition of antibiotics. The antinutrients had no effects, either on starch digestion or on fiber ferme

Effects of Boiling and Storage on Dietary Fibre and Digestible Carbohydrates in Various Cultivars of Carrots

The influence of boiling and storage on dietary fibre and digestible carbohydrates was investigated in eight different carrot cultivars. The content of total dietary fibre was in the range 252-291 g kg-1 DW and was generally at the higher end for the early cultivars and at the lower end for the late ones. During storage, there was a decrease in the soluble fibre content in all cultivars and genera

Cancer biomarker assessment using evolutionary rough multi-objective optimization algorithm

A hybrid unsupervised learning algorithm, which is termed as Evolutionary Rough Multi-Objective Optimization (ERMOO) algorithm, is proposed in this chapter. It comprises a judicious integration of the principles of the rough sets theory with the archived multi-objective simulated annealing approach. While the concept of boundary approximations of rough sets in this implementation deals with the in

A comparison of cost-effectiveness of computer-assisted 2-and 3-dimensional planning techniques in orthognathic surgery

The aim of this randomised controlled trial was to compare the costs and benefits of computer-based 2-dimensional and 3-dimensional predictions in orthognathic surgery.Subjects aged 18–30 years with severe class III malocclusion had their treatment planned with both 2- and 3-dimensional techniques. They were randomised in a 1:1 ratio for one or other planning technique. Costs (financial, time, and

The reversal of human phylogeny : Homo left Africa as erectus, came back as sapiens sapiens

Background: The molecular out of Africa hypothesis, OOAH, has been considered as an established fact amid population geneticists for some 25–30 years despite the early concern with it among phylogeneticists with experience beyond that of Homo. The palaeontological support for the hypothesis is also questionable, a circumstance that in the light of expanding Eurasian palaeontological knowledge has

Towards a model for robust design and design process in one-of-a-kind production of large power transformers

The robust engineering seeks for design of products and processes insensitive to changes in the work environment and to the variation of the components. The robust process has built-in mechanisms to detect potential errors on time, to eliminate them and to initiate all the necessary measures to ensure the same error does not occur again. One-of-a-kind production is characterised by unique products

Predicting the rate of oxygen consumption during the 3-minute constant-rate stair stepping and shuttle tests in people with chronic obstructive pulmonary disease

Background: The 3-minute constant-rate stair stepping (3-min CRSST) and constant-speed shuttle tests (3-min CSST) were developed to assess breathlessness in response to a standardized exercise stimulus. Estimating the rate of oxygen consumption (V'O2) during these tests would assist clinicians to relate the stepping/shuttle speeds that elicit breathlessness to daily physical activities with a simi

Critical performativity in practice : the chronicle as a vehicle for achieving social impact

The concept of critical performativity–efforts to make critical research more relevant for groups outside academia and develop and communicate action-relevant critical insights with some potential effect–has received considerable interest. Much of this has focused on debates about the core concept and principles. This paper argues for the need to “do”–more than talk about–critical performativity a

‘Big is not always beautiful’ : Family farms and capitalism

Large landed estates often have an interesting history, worth digging into. Labour hiring is usually regarded as the capitalist relation of production. A classic study from the 1980s of salad farms in California, United States of America (USA), showed that farm workers were recruited from highly segmented niches in the labour market, with illegal immigrants at the lower rungs doing the most tediou

Educating towards the prudent entrepreneurial self – an educational journey including agency and social awareness to handle the unknown

Purpose: This paper explores the idea of the prudent entrepreneurial self, through re-conceptualizing prudence into the domain of entrepreneurial education, to unite the two processes of becoming enterprising and entrepreneurial. It is argued that developing a capacity for prudence among graduates involves past, present and conjecture forms of knowledge that the authors find in the interplay betwe

Give older persons a voice in the society—by using information compiled during preventive home visits on a societal level

Preventive home visits (PHVs) are offered to older persons with the purpose of promoting health and preventing risks on an individual level. However, aspects of health need to be considered on a societal level as well. This study aims to get a deeper understanding of perceptions of the usability of the information compiled during the PHVs to promote health, among older persons, on a societal level

Enteroviruses and Type 1 Diabetes : Multiple Mechanisms and Factors?

Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by insulin deficiency and resultant hyperglycemia. Complex interactions of genetic and environmental factors trigger the onset of autoimmune mechanisms responsible for development of autoimmunity to β cell antigens and subsequent development of T1D. A potential role of virus infections has long been hypothesized, and growing evide

Microsurgical vasovasostomy: An option for men with post vasectomy psychological distress

Vasectomy is a practical and straightforward approach to birth control. This paper presented a 31-year-old patient who desired torestore his fertility five years after being vasectomized. He met several obstacles. He developed severe psychological distress withsymptoms of stress, anxiety, and aggression. He underwent microsurgical vasovasostomy, and vassal patency was confirmedby return of spermat

Allergic contact dermatitis caused by dipropylene glycol diacrylate in the Omnipod® insulin pump

Background: Cases of allergic contact dermatitis (ACD) caused by isobornyl acrylate (IBOA) in the Omnipod® insulin pump have previously been reported. Objectives: To present three cases of patients with ACD caused by a new allergen in the pump, and results from chemical analyses. Methods: Omnipod pumps from different batches were analysed by gas chromatography–mass spectrometry. Aimed testing, wit