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Evolutionary and functional studies of protein H: a surface molecule of Streptococcus pyogenes

Popular Abstract in Swedish Protein H - ett bakteriellt ytprotein med förmåga att binda till olika proteiner hos människa Bakgrund I vårt dagliga liv omges vi av bakterier av många olika slag. Flertalet av dessa är normalt ofarliga och många utgör den så kallade normalfloran hos människa. En del bakterier kan under vissa förhållanden ge upphov till infektion och sjukdom, men för att åstadkomma d

Energy Storage & Conversion

Sustainable energy storage and conversion explores innovative methods to efficiently store and transform energy from various renewable sources. It focuses on technologies like advanced batteries, hydrogen production, fuel cells, and thermochemical systems as well as safety aspects of battery storage systems. Research aims to enhance energy density, reduce costs, and improve scalability, enabling r

https://www.energy.lth.se/research/energy-storage-conversion - 2026-05-13

Group G streptococcal IgG binding molecules FOG and protein G have different impacts on opsonization by C1q

Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i

Potentialities of manganese ore and iron-carbon particles for pharmaceuticals and personal care products removal in electroactive constructed wetland

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Ann-Christine Hartzén

Docent Kontaktinformation E-post: ann-christine [dot] hartzen [at] har [dot] lu [dot] se Telefon: +46 46 222 78 45Organisation Institutionen för handelsrätt Hämtställe: 10 WebbplatsAnn-Christine Hartzéns profil i Lunds universitets forskningsportalAndra roller Forskare Affärsrättsligt centrum vid Lunds Universitet, ACLU Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtre

https://www.ehl.lu.se/ann-christine-hartzen - 2026-05-14

Monte Carlo simulations of a clay inspired model suspension: the role of rim charge

We present a theoretical investigation of a model clay dispersion in 1-1 salt solutions by varying the particle volume fraction and ionic strength as well as the charge distribution on the clay platelets. The platelets are modeled as discs with charged sites distributed on a hexagonal lattice. The edge sites can be positively charged while the remaining sites are negative giving rise to a strong c

Factors associated with good health among older persons who received a preventive home visit : a cross-sectional study

Background: The ageing population is increasing worldwide, and this trend is bringing challenges both for the older person and for society. In order to meet the challenges a comprehensive approach is needed involving both health promotion and risk prevention. The preventive home visit is a public health intervention used around the world with the purpose of promoting health and preventing risk amo

Women on the road : Regendering Narratives of Mobility

Popular Abstract in Swedish Traditionellt sett är resande en maskulin aktivitet. I det här sammanhanget betyder det att resan för en euro-amerikansk man ses som en identitetsskapande process som formar honom som subjekt. Denna process förutsätter att kvinnan figurerar i marginalen, i det stereotypiska fallet som sexobjekt eller väntande hustru/moder. Genom att ersätta män med kvinnor i huvudrollerThis thesis is founded on the premise that traditional discourses of travel and mobility are inherently masculinist, that is, travel is seen as a masculinity rite-of passage for the Euro-American male, shaping his subjectivity through the othering and marginalization of women. Taking Jack Kerouac’s On the Road (1957), the epitome of masculinist travel literature, as a starting point for an examina

Specialgjorda antikroppar i kampen mot infektioner – Vetenskap och Hälsa

Specialgjorda antikroppar i kampen mot infektioner – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Specialgjorda antikroppar i kampen mot infektioner 2025-05-21 Bilden är en illustration av ett SARS-CoV-2-virus (rosa) De gula utskotten på dess yta är de så kallade spike-proteinerna. De blå

https://www.vetenskaphalsa.se/specialgjorda-antikroppar-i-kampen-mot-infektioner/ - 2026-05-14

Asymptotic Performance Analysis of Distributed Non-Bayesian Quickest Change Detection with Energy Harvesting Sensors

This paper focuses on the distributed non-Bayesian quickest change detection based on the Cumulative Sum (CUSUM) algorithm in an energy harvesting wireless sensor network (WSN), where the distributions before and after the change point are assumed to be known. Each sensor is powered by randomly available harvested energy from the surroundings. It samples the observation signal and computes the log