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Red-Haired People's Altered Responsiveness to Pain, Analgesics, and Hypnotics : Myth or Fact?-A Narrative Review

Red hair has been linked to altered sensitivity to pain, analgesics, and hypnotics. This alteration may be impacted by variants in the melanocortin-1 receptor (MC1R) gene, which are mainly found in redheads. The aim of this narrative review was to explore and present the current state of knowledge on red hair and its plausible associations with altered responsiveness to pain, analgesics, and hypno

Pericyte response to ischemic stroke precedes endothelial cell death and blood-brain barrier breakdown

Stroke is one of the leading causes of death and disability, yet the cellular response to the ischemic insult is poorly understood limiting therapeutic options. Brain pericytes are crucial for maintaining blood-brain barrier (BBB) integrity and are known to be one of the first responders to ischemic stroke. The exact timeline of cellular events after stroke, however, remains elusive. Using the per

Innovations, informality, and the global south : A thematic analysis of past research and future directions

The informal sector of the global south has lately started to gain attention from innovation and development studies scholars. Studies highlighting the determinants, barriers, social processes, and institutions that influence innovations in the informal sector have enriched the discussion on the topic. This paper analyzes the existing body of knowledge at the intersection of the informal sector, i

Breaking barriers : Paving the path to sustainable fashion – insights for a greener apparel and textile sector

Purpose: The apparel and textile sector poses a significant environmental challenge due to its substantial contribution to pollution in the form of air, water and soil pollution. To combat these issues, the adoption of sustainable practices is essential. This study aims to identify and analyse the barriers that hinder the progress of sustainability in the apparel and textile industry. By consultin

In situ characterization of stresses, deformation and fracture of thin films using transmission X-ray nanodiffraction microscopy

The use of hard X-ray transmission nano- and microdiffraction to perform in situ stress and strain measurements during deformation has recently been demonstrated and used to investigate many thin film systems. Here a newly commissioned sample environment based on a commercially available nanoindenter is presented, which is available at the NanoMAX beamline at the MAX IV synchrotron. Using X-ray na

Sanctity and Female Authorship : Birgitta of Sweden & Catherine of Siena

Birgitta of Sweden (Birgitta Birgersdotter, 1302/03-1373) and her younger contemporary Catherine of Siena (Caterina Benincasa, 1347-1380) form the most powerful and influential female duo in European history. Both enjoyed saintly reputations in life, while acting as the charismatic leaders of a considerable group of followers consisting of clergy as well as mighty secular men and women. They are a

Globalisation in reverse? Reconfiguring the geographies of value chains and production networks

Standing at a crossroads, where ongoing 'slowbalisation' coincides with new forces such as the outbreak of the Covid-19 pandemic, heightened geopolitical tensions, the emergence of disruptive technologies and the increasing urgency of addressing environmental challenges, many important questions remain unsolved regarding the nature and impact of the current economic globalisation. This special iss

A posterior convergence rate theorem for general Markov chains

This paper establishes a posterior convergence rate theorem for general Markov chains. Our approach is based on the Hausdorff α-entropy introduced by Xing (Electronic Journal of Statistics 2:848–62, 2008) and Xing and Ranneby (Journal of Statistical Planning and Inference 139 (7):2479–89, 2009). As an application we illustrate our results on a non linear autoregressive model.

Host Immunity-Microbiota-Virus Interactions at the Intestinal Mucosal surface in Health and Disease

The presence of viral immune triggers at the intestinal mucosa can have multipleglobal effects on intestinal integrity, including relative protection fromsubsequent inflammatory bowel disease. During the last century, the westernworld has achieved a remarkable success in preventing infectious diseases,which increased the general life expectancy dramatically. However, theincidence and prevalence of

Are "cases", "waves", "tests" and "modeling" deceiving indicators to describe the COVID-19 pandemic?

This commentary elaborates on different methodological aspects complicating the interpretation of epidemiological data related to the current COVID-19 pandemic, thus preventing reliable within and across-country estimates. Firstly, an inaccuracy of epidemiological data maybe arguably be attributed to passive surveillance, a relatively long incubation period during which infected individuals can st

The Question of Adoption : ‘Divided’ Korea, ‘Neutral’ Sweden, and Cold War Geopolitics, 1964–75

This article examines the early development of South Korean intercountry adoption to Sweden. It focuses particularly on two disruptions in the movement of children between the two nations, drawing on archival sources in Sweden, South Korea, and Denmark. The article demonstrates that South Korean–Swedish adoption was deeply bound up in the shifting Cold War relations within and between the Korean p

Linked Transitions in Later Life–Retiring as Transitional Assemblage in the COVID-19 Pandemic

The COVID-19 pandemic challenges expectations of retirement. In this paper, we ask: How is the retirement transition experienced in the everyday lives of older adults during pandemic as compared to pre-pandemic times? The paper draws on 15 semi-structured interviews with adults aged 60–75 years living in Germany within the first year of the COVID-19 pandemic, which were analyzed based on social co

Cardiovascular and Cerebrovascular Events After Parathyroidectomy in Patients on Renal Replacement Therapy

Background: A majority of patients with end-stage renal disease suffer from secondary hyperparathyroidism, which is associated with osteoporosis and cardiovascular disease. Parathyroidectomy (PTX) is often necessary despite medical treatment. However, the effect of PTX on cardio- and cerebrovascular events (CVE) remains unclear. Data on the effect of PTX from population-based studies are scarce. S

Values, Processes and Decision-Making in Boards of Directors

This thesis aims to advance our understanding of how directors’ values influence board decision-making and firm behavior by developing and testing a model that integrates insights from behavioral perspectives on boards of directors and corporate governance. Ideally, boards engage in intensive and open discussions that utilize the full cognitive capacity of their members. However, in practice, they

Chinese Youth in Climate Action: Exploring the Influence of China’s “3060” Decarbonization Target on Urban Youth Climate Action Intentions

China's "3060" target for carbon neutrality needs public action. This study explores how this goal influences urban Chinese youth's intention to take climate action. Based on surveys and interviews, this study found a positive link between them. While perceived policy benefits motivate youth to act, barriers include concerns about green product accessibility and lack of infrastru