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Centrifugal sedimentation of an ideal suspension in a rotating tube or basket can be modelled by an initial-boundary-value problem for a scalar conservation law with a nonconvex flux function. The sought unknown is the volume fraction of solids as function of radial distance and time for constant initial data. The method of characteristics is used to construct entropy solutions. The qualitatively

Introduction: Detection of circulating tumour cells (CTCs) in peripheral blood has an established prognostic significance in patients with metastatic breast cancer. Change in the number of detected CTCs is also an indication of response to therapy. Characterisation of CTCs could provide easily accessible treatment predictive information of present cancer cells within the patient and could reveal i

The association between contextual factors and health inequalities is well documented, also in Brazil. However, questions about how contextual factors actually affect health and well-being persist. The aim of this qualitative study was to explore how contextual factors-i.e., social stratification and neighborhood opportunity structures-are manifested in the lives of the residents of a vulnerable d

There is a great interest within the research community to understand the structure-function relationship for intrinsically disordered proteins (IDPs); however, the heterogeneous distribution of conformations that IDPs can adopt limits the applicability of conventional structural biology methods. Here, scattering techniques, such as small-angle X-ray scattering, can contribute. In this chapter, we

We present CNFgen, a generator of combinatorial benchmarks in DIMACS and OPB format. The proof complexity literature is a rich source not only of hard instances but also of instances that are theoretically easy but “extremal” in different ways, and therefore of potential interest in the context of SAT solving. Since most of these formulas appear not to be very well known in the SAT community, howe

Background: The Evaluation in Ayres Sensory Integration ® (EASI) is a performance-based assessment tool, aiming to assess sensory perception, sensory reactivity, postural/ocular/bilateral integration, and praxis in children aged 3–12 years. These types of tests are currently not available in Swedish. A structured, multistep process of translation is crucial for maintaining equivalence between the

Intestinal homeostasis and induction of systemic tolerance to fed Ags (i.e., oral tolerance) rely on the steady-state migration of small intestinal lamina propria dendritic cells (DCs) into draining mesenteric lymph nodes (MLN). The majority of these migratory DCs express the α integrin chain CD103, and in this study we demonstrate that the steady-state mobilization of CD103(+) DCs into the MLN is

The purpose of this paper is to study microlocal conditions for inclusion relations between the ranges of square systems of pseudodifferential operators which fail to be locally solvable. The work is an extension of earlier results for the scalar case in this direction, where analogues of results by L. Hormander about inclusion relations between the ranges of first order differential operators wit

Oxygen toxicity is thought to be an important factor involved in development of bronchopulmonary dysplasia (BPD) in the very preterm infant. Glutathione (GSH) plays a major role in the antioxidant defense system in the preterm lung and there are theoretical implications that N-acetylcysteine (NAC) treatment could improve its function. The purpose of this study was to investigate whether NAC treatm

The complement system is activated in response to tissue injury. During wound healing, complement activation seems beneficial in acute wounds but may be detrimental in chronic wounds. We found that the epidermal expression of many complement components was only increased to a minor extent in skin wounds in vivo and in cultured keratinocytes after exposure to supernatant from stimulated mononuclear

This chapter explores how nursing home managers grapple with local manifestations of the wicked problems that plague elderly care. It shows the tension between managers' lofty ideals of high-quality, individualized care and their continuous struggle to handle very basic troubles that ultimately appear to be grounded in a lack of resources, such as high personnel turnover and staff complaints about

A nanosized hydroxyapatite (HA) modification on polyetheretherketone (PEEK) using a novel spin coating technique was investigated in a rabbit model. Spin coating technique creates a 20–40 nm thick layer of nanosized HA particles with similar shape, size, and crystallinity as human bone. Some implants were designed with a perforating hole in the apical region to mimic a fusion chamber of a spinal i

A common assumption in product value literature is that authenticity is what contemporary consumers value the most. However, as this paper illustrates, the meaning of authenticity is unclear, and the term appears foreign to product development practitioners. The purpose of this paper is to explore in what ways product development professionals talk about product value in general and how this relat