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The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The
Cerebrovascular disease may be linked with vascular autoregulation in aging. The aim of this study was to examine relation between nocturnal blood pressure (BP) fall and cerebral blood flow (CBF) changes in elderly men. The prospective 'Men born in 1914' cohort study has been in progress since 1968 and included 809 subjects. After 14 years from the last follow up, 97 subjects reached the age of 82
We have recently found a correlation between contact allergy to gold sodium thiosulphate (GSTS) and gold concentration in the blood (B-Au) in a stented population: the higher the B-Au, the stronger the patch-test reaction. To further investigate the correlation between B-Au and patch-test reactivity to gold. In this provocation control cross-over trial of 24 patients with dermatitis with a known c
Ovarian cancer is usually found at a late stage when the prognosis is often bad. Relative survival rates decrease with tumor stage or grade, and the 5-year survival rate for women with carcinoma is only 38%. Thus, there is a great need to find biomarkers that can be used to carry out routine screening, especially in high-risk patient groups. Here, we present a large-scale study of 64 tissue sample
A prevalence of hepatitis C virus (HCV) antibodies of 12% was found in 276 patients from 11 dialysis units. Between zero and 22% of the patients in the different units were anti-HCV positive. The epidemiology of HCV was studied in two units during a 2 year period by antibody assays and the polymerase chain reaction and correlated with clinical manifestations. Two types of epidemiologic patterns we
In type-1 diabetes mellitus (T1DM) with diabetic nephropathy (DN), accumulation of abnormal proteins in the kidney and other tissues may derive from constitutive alterations of intracellular protein recognition, assembly, and turnover. We characterized the proteins involved in these functions in cultured skin fibroblasts from long-term T1DM patients with [DN+] or without [DN-] nephropathy but simi
Popular Abstract in Swedish Något tillspetsat förefaller varje kommun driva utvecklingsarbete inriktat på verksamhetsmått. Är så inte fallet är ansvariga snabba att betona att verksamhetsmått är viktigt och att de precis har beslutat om ett större måttprojekt. Denna bok ger en bild av i vilken omfattning fyra gatukontor utformar och använder verksamhetsmått. Boken innehåller också beskrivningar ocThe purpose of this study is to develop a frame of reference within which formal control system performance measures can be described and their design and use can be analyzed for control systems in municipalities. From a cybernetic control approach measures are used as instruments to plan and gain feedback from employee actions, and adjust them to the internal and external environment of which the
Compared to truly negative cultures, false-positive blood cultures not only increase laboratory work but also prolong lengths of patient stay and use of broad-spectrum antibiotics, both of which are likely to increase antibiotic resistance and patient morbidity. The increased patient suffering and surplus costs caused by blood culture contamination motivate substantial measures to decrease the rat
The thesis aims to: (a) broaden the knowledge base that makes up the foundation for decisions with regard to how traffic law enforcement is best outlined, as well as increasing the understanding of how the shaping of different public instruments of control affects the chances of success; and (b) contribute to the development of theory and methodology within sociology of law. The relationship betwe
The objective of this exploratory study was to develop signal processing methods for assisting in the diagnosis of arteriovenous fistula stenosis on patients suffering from end-stage renal disease and undergoing haemodialysis treatments. The proposed method is based on the classification of vessels sounds utilizing parameter extraction from wavelets transform coefficients. The coefficients energy
Cholera toxin (CT) binds to GM1-ganglioside receptors present on all nucleated cells. Despite this, it is a very potent mucosal adjuvant that has a dramatic impact on immune cells, as well as nerve and epithelial cells, causing diarrhea. This fact has hampered our understanding of whether the adjuvanticity of CT is direct or indirect, as cells that bind CT may or may not be involved in its adjuvan
The low specificity of screening ELISAs for antibodies to hepatitis C virus in blood donors has called for confirmatory tests. Two types of supplementary antibody assays are available, recombinant immunoblot assays (RIBA-1 and RIBA-2) and an antibody consumption test referred to as a neutralization assay. Amplification of viral nucleic acid by the polymerase chain reaction (PCR) provides an antibo
OBJECTIVE: The overall objective was to unfold the phenomenon of interrater agreement: to identify potential sources of variation in agreement data and to explore how they can be statistically accounted for. The ultimate aim was to propose recommendations for in-depth examination of agreement to improve the reliability of assessment instruments. STUDY DESIGN AND SETTING: Using a sample where 1
Wnt5a is a non-canonical Wnt protein that is expressed at elevated levels in inflammatory conditions. Its role in inflammation remains unclear, although it is known that Wnt5a is expressed at a higher level in monocyte-derived myeloid dendritic cells (Mo-mDCs) than in monocytes and macrophages. The function of Wnt5a in dendritic cells (DCs) remains relatively unexplored. Here, we found that under
We propose a method of reducing the switching noise in the substrate of an integrated circuit. The main idea is to design the digital circuits to obtain a periodic supply current with the same period as the clock. This property locates the frequency components of the switching noise above the clock frequency. Differential return-to-zero signaling is used to reduce the data-dependency of the curren
This dissertation offers a unique examination of Muslim masculinities and marginalized sexualities in Lebanon, and is a contribution to the growing body of gay and lesbian studies with a focus on Muslims living in The Middle East. It contributes to the theoretical and methodological development of Islamic studies by introducing and using a queer approach to study marginalized sexualities in relati
Searching for a possible explanation for the phenotypic heterogeneity in IgG3 deficiency, we studied the antibody response to a polysaccharide and a protein antigen in IgG3-deficient (IgG3d) adults after vaccination with Haemophilus influenzae type b capsular polysaccharide (Hib CP) conjugated to tetanus toxoid. Distribution of isotypes, idiotypes, clonotypes, and Gm allotypes were compared. All t
