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Angular dispersion and temporal change of femtosecond pulses from misaligned pulse compressors

A misaligned stretcher or compressor in a chirped pulse amplification laser introduces residual angular dispersion into the beam, resulting in temporal distortion of the pulse. We demonstrate that an imaging spectrograph is capable for Measuring the angular dispersion of a laser beam by an accuracy of 0.2 murad/min. Using this technique, the analytical expressions of residual angular dispersion of

CD44/CD70 blockade and anti-CD154/LFA-1 treatment synergistically suppress accelerated rejection and prolong cardiac allograft survival in mice.

Current treatments that are efficient in controlling effector T cells responses to allografts have limited efficacy on the accelerated rejection mediated by memory T cells. Effective targeting of alloreactive memory T cells may therefore be explored to improve therapeutic approaches towards solving this problem. In this study, we investigated the synergistic effect of CD44/CD70 blockade and anti-C

A Novel C3 Mutation Causing Increased Formation of the C3 Convertase in Familial Atypical Hemolytic Uremic Syndrome.

Atypical hemolytic uremic syndrome has been associated with dysregulation of the alternative complement pathway. In this study, a novel heterozygous C3 mutation was identified in a factor B-binding region in exon 41, V1636A (4973 T > C). The mutation was found in three family members affected with late-onset atypical hemolytic uremic syndrome and symptoms of glomerulonephritis. All three patients

Acoustical detection of venous stenosis in Hemodialysis patients using principal component analysis

In this paper, a feature extraction method based on principal component analysis was developed for classification of the vascular access’s condition in hemodialysis patients. The assessment of the method was carried out by discriminating between before and after angioplasty sound recordings as well as before angioplasty and reference recordings. The results showed that when before and after angiop

Structuring uncertainty: sponsoring innovation and creativity

Dynamic and complex decision-making environments may involve high levels of uncertainty. Such uncertainty may lead to difficulty within decision-making processes. High levels of uncertainty in decision-making occur in a dynamic and complex environment. While decision-making is needed as a response to uncertainty, this may lead to difficulty within decision-making processes. Furthermore, there are

The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells.

Moraxella catarrhalis is a major cause of exacerbations of chronic obstructive pulmonary disease (COPD) and emphysema. M. catarrhalis–specific UspA1 and the epithelial carcinoembryonic antigen-related cell adhesion molecule (CEACAM1) were required to induce apoptosis. M. catarrhalis–induced apoptosis was significantly enhanced in HeLa cells stably transfected with CEACAM1, compared with HeLa cells

Distinct and overlapping patterns of cytokine regulation of thymic and bone marrow-derived NK cell development.

Although bone marrow (BM) represents the main site for postnatal NK cell development, recently a distinct thymic-dependent NK cell pathway was identified. These studies were designed to investigate the role of cytokines in regulation of thymic NK cells and to compare with established regulatory pathways of BM-dependent NK cell compartment. The common cytokine receptor gamma-chain (Il2rg) essential

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis.

Antibodies to citrulline-modified proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear. To obtain insight into this question, a panel of mouse monoclonal antibodies was generated against a major triple helical collagen type II (CII) epitope (position 359-369; ARGLTGRPGDA) with or without arginines modified by cit

ACCOUNTING SOLUTIONS USE FOR BUDGETING IN ERP,

We explore whether off-the-shelf accounting solutions are used or not used in management control. This study explores the usage of accounting solutions such as ERP, “hybrid ERP”, and “best-ofbreed” (BoB). Previous research highlights the problem that ERP has a “moderate” impact on management control but no study addresses whether hybrid ERP and BoB adopters experience the same problem. The explora

High sexual risk taking and diverging trends of HIV-1 and HIV-2 in the military of Guinea Bissau

BACKGROUND: HIV and other sexually transmitted infections are a growing problem in the military personnel of Africa, and information about this problem in Guinea-Bissau is lacking. The aims of this study were to determine the prevalence and trends of the HIV epidemics in the military forces of Guinea Bissau and to explore possible risk factors for HIV infection. METHODOLOGY: Repeated cross-sectio

Mortality and tumour morbidity among Swedish market gardeners and orchardists

In order to investigate possible effects of exposure to pesticides, mainly fungicides and insecticides, we studied a cohort of 2370 subjects, who, during the period 1965-1982, had been members of a horticulturists' trade association (market gardeners and orchardists). Compared to a regional reference population, total mortality ( 542 deaths; standardized mortality morbidity ratio, SMR = 0.8 ; 95 %