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Background: A previously discovered mutant of Saccharomyces cerevisiae alcohol dehydrogenase 1 (Adh1p) was shown to enable a unique NADH-dependent reduction of 5-hydroxymethylfurfural (HMF), a well-known inhibitor of yeast fermentation. In the present study, site-directed mutagenesis of both native and mutated ADH1 genes was performed in order to identify the key amino acids involved in this subst

Background: The ICF core sets for patients with Rheumatoid Arthritis ( RA) acknowledge sexual function and intimate relationships as important since the patients' sexual health can be affected by the disease. About 36-70% of all RA-patients experience a reduced sexual health, and their perceived problems are directly or indirectly caused by their disease. Physiotherapy is often used as non-pharmac

A highly efficient anode for glucose biofuel cells has been developed by a combination of pyranose dehydrogenase from Agaricus meleagris (AmPDH) and cellobiose dehydrogenase from Myriococcum thermophilum (MtCDH). These two enzymes differ in how they oxidize glucose. AmPDH oxidizes glucose at the C(2) and C(3) carbon, whereas MtCDH at the C(1) carbon. Both enzymes oxidize efficiently a number of ot

It has been a common practice both in Sweden and worldwide to enclose nuclear reactors with prestressed concrete structures. The prestress level decreases with time from its initial value due to various degradation mechanisms. To ensure that the prestress level is sufficient the tendon force is measured at regular in-service inspections. The intention with this paper is to present a reliability-ba

Surgery or radiation therapy remain the standard curative treatments for newly diagnosed prostate cancer patients. Nonetheless, these aggressive treatments are associated with decreased quality of life with altered sexual and urinary functions. The objective was a systematic review of active surveillance protocols to investigate the role of histopathology and molecular markers in the active survei

In Sweden and in other countries, building owners are encouraged to help reduce energy consumption, both in order to contribute to national energy saving goals and, in terms of their own interests, to reduce the costs of heating and operation of the building. However, it is important to pursue the most optimal strategy available so as to achieve cost-effective energy usage while simultaneously mai

Nocturnal hawkmoths are known for impressive visually guided behaviours in dim light, such as hovering while feeding from nectar-bearing flowers. This requires tight visual feedback to estimate and counter relative motion. Discrimination of low velocities, as required for stable hovering flight, is fundamentally limited by spatial resolution, yet in the evolution of eyes for nocturnal vision, main

Adsorption of glycine on Pt{111} under UHV conditions and in different aqueous environments was studied by XPS (UHV and ambient pressure) and NEXAFS. Under UHV conditions, glycine adsorbs in its neutral molecular state up to about 0.15 ML Further deposition leads to the formation of an additional zwitterionic species, which is in direct contact with the substrate surface, followed by the growth of

Planning for future needs has traditionally been considered to be restricted to human cognition. Although recent studies on great ape and corvid cognition challenge this belief, the phylogenesis of human planning remains largely unknown. The complex skill for future planning has not yet been satisfactorily established in any other extant primate species than our own. In humans, planning for future

Freshwater blooms of cyanobacteria (blue-green algae) in source waters are generally composed of several different strains with the capability to produce a variety of toxins. The major exposure routes for humans are direct contact with recreational waters and ingestion of drinking water not efficiently treated. The ultra high pressure liquid chromatography tandem mass spectrometry based analytical

Situated in Vietnam’s transitional vacuum in its urban cores Hanoi and Ho Chi Minh City, this study is rooted in the aim to understand the emerging variants of coworking spaces currently proliferating across the country. This aim is realized by conducting a multiple case study and semi-structured interviews with nine founders, community managers and users of coworking spaces from heterogeneous bac

Förändringar i hjärnan vid avsaknad av CYP27A1 CYP27A1 är en gen vars färdiga protein är involverat i nedbrytning av kolesterol och gallsyrasyntes. Avsaknad av CYP27A1 eller produktion av en dysfunktionell variant av proteinet i människor resulterar i sjukdomen Cerebrotendinös xantomatos (CTX). CTX är en sjukdom som karaktäriseras av grumling av ögats lins, lipidinlagringar i form av knutor i senCYP27A1 is an important enzyme in cholesterol catabolism and bile acid biosynthesis. Deficiency of this enzyme in human leads to the disease Cerebrotendinous xanthomatosis (CTX), which is a recessively inherited lipid storage disorder characterized by symptoms such as cataracts, tendon xanthomas and progressive neurological syndrome. The underlying cause for the neurological symptoms is not well u

Abstract This study examines if extramural English (EE) has a positive effect on L2 vocabulary acquisition of young Swedish L2 learners (N = 24) of English (age 8-10). It examines the correlation between the amount of time spent on EE and scores on the Picture Vocabulary Size Test (PVST), which measures receptive vocabulary knowledge. Since earlier research on older Swedish L2 learners of English

The main purpose of this study was to investigate the violence men experienced from their female partner. We have through semi-structured interviews with nine men in heterosexual relationships in Sweden got an insight of men's experience of domestic violence. Our focus was the men's experience of the violence, how men experience the outside world's view of the men who are exposed to vi

The donor community has increasingly acknowledged the principles of adaptability and flexibility as part of promoting development cooperation effectiveness. However, limited research has investigated the implementation of these principles, particularly by intermediary civil society organizations (CSOs). Wishing to address these gaps, this thesis examines the implementation of the principles by Swe