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ON THE ESTIMATION OF RADIATION-INDUCED CANCER RISKS FROM VERY LOW DOSES OF RADIATION AND HOW TO COMMUNICATE THESE RISKS.

The article is intended to give a short overview of epidemiological data on cancer risks associated with very low absorbed doses of ionising radiation. The linear no-threshold (LNT) approach to estimate cancer risks involves the use of epidemiological data at higher doses (>100 mSv), but is supported by data from lower exposure of more sensitive population groups like fetuses and children and the

Multimeric Lactoside "Click Clusters" as Tools to Investigate the Effect of Linker Length in Specific Interactions with Peanut Lectin, Galectin-1, and-3

Multimeric lactosides based on carbohydrate scaffolds with valencies ranging from 1 to 4 and different linker lengths were synthesized by a copper-catalyzed azide-alkyne cycloaddition (CuAAC). The binding affinities and crosslinking abilities of the new "click clusters" toward biologically relevant galectins (gal-1, gal-3) and peanut lectin were evaluated by fluorescent polarization assay (FPA) an

Paper II - Dirt, dates and DNA: OSL and radiocarbon chronologies of perennially-frozen sediments in Siberia, and their implications for sedimentary ancient DNA studies

Abstract in UndeterminedThe sedimentary ancient DNA (sedaDNA) technique offers a potentially invaluable means of investigating species evolution and extinction dynamics in high-latitude environments. An implicit assumption of the sedaDNA approach is that the extracted DNA is autochthonous with the host deposit and that it has not been physically transported from older source deposits or reworked w

Regional biomass planning – Helping to realise national renewable energy goals?

Biomass will make a vital contribution to the EU renewable energy targets, however large amounts need to be mobilised to achieve policy goals. To promote action, the European Commission sent a firm call to member states for coordinated biomass strategies and plans, and engagement of sub-national actors. This paper examines how regional level biomass planning can benefit national planning and EU ta

Reactivity of Fe from a natural stream water towards As(V)

Interactions between iron (Fe) and arsenic (As) play a vital role in aquatic and terrestrial ecosystems influencing the reactivity and transport of arsenic. A key aspect is the effect of natural organic matter (NOM) on these interactions, and previous investigations have reported the existence of ternary As-Fe-NOM species. In this study, the reactivity of Fe, from a boreal stream water, towards As

Effect of postconditioning on infarct size in patients with ST elevation myocardial infarction

Background Small studies suggest that postconditioning reperfusion interrupted by brief repetitive cycles of reocclusions, may protect the myocardium in the clinical setting. Objective To test the hypothesis that postconditioning limits infarct size in relation to the area at risk in patients with ST elevation myocardial infarction (STEMI). Methods 76 patients (aged 37-87 years) eligible for prima

Long-term evolution of three-planet systems to the post-main sequence and beyond

We study the stability of systems of three giant planets orbiting 3-8 M☉ stars at orbital distances of >10 au as the host star ages through the main sequence (MS) and well into the white dwarf (WD) stage. Systems are stable on the MS if the planets are separated by more than ~9 Hill radii. Most systems surviving the MS will remain stable until the WD phase, although planets scattered on to small p

Ventilation of the Paranasal Sinuses. A study using the 133-Xenon Washout Technique

Popular Abstract in Swedish Undersökning av bihåleventilation med 133-xenon washout teknik och gammakamera med tomografi, gör det möjligt att mäta ventilationen även i de djupa bihålorna som bakre ethmoidalsinus och sphenoidalsinus. Mätningar visar reproducerbara resultat hos friska försökspersoner där normala variationer i näsandningsmotstånd och kroppsläge ej påverkar mätresultaten. BihåleventilA noninvasive 133-xenon washout technique was used to evaluate the ventilation of the paranasal sinuses in healthy subjects and in patients with sinus disease. A mixture of air and 133-xenon is insufflated into the nasal cavities and passage into the sinuses is facilitated by a pressure increase created by letting the subjects inflate a balloon. A scintillation camera allowing single photon emissi

Predicting Two-lane Highway Crashes Using Crash Opportunities: A Newly Defined Measure of Exposure

There is general consensus among road safety researchers that the crash count is not linear with respect to the traffic volume. However, the now-preferred practice of estimating exponents on traffic volume not only results in parameters that cannot be confidently applied in other contexts, but also offers very little insight into the relationship. This paper describes a preliminary investigation o

The Last Judgement in Medieval Latin Model Sermons

The article examines specimens from five Latin sermon collections that were widely used as models for sermon composition in the later Middle Ages. Four of the collections were studied in incunable editions. One of the results is that the only day of the eclesiastical year on which one finds a more or less regular discussion of the Last Judgement is the first or second Sunday of Advent. The subject

Wnt-5a Signalling in Human Mammary Cells: Implications for the Development of Breast Cancer

Popular Abstract in Swedish Wnt-5a-genens betydelse för bröstcellernas normala funktion och för uppkomsten av bröstcancer I min avhandling har jag studerat en i bröstcancersammanhang hittills föga undersökt gen, Wnt-5a. Benämningen Wnt har bildats genom en sammanslagning av "Wingless" (den första identifierade Wnt-genen som orsakar vinglöshet hos bananflugan) och "Int" (från "Integration site" fö

Essays on Negotiation and Renegotiation in Bertrand Games

This licentiate thesis consists of three separate papers that investigate the effects of negotiation and renegotiation in Bertrand games. The first paper investigates collusion in an infinitely repeated Bertrand duopoly where firms have different discount factors. In order to study how a collusive agreement is reached we model the equilibrium selection as an alternating-offer bargaining game. The

The role of leucine-rich repeat glycoproteins/proteoglycans in the assembly of collagen matrices

Popular Abstract in Swedish Bindväv är samlingsnamnet på de vävnader som bygger upp ben, brosk, senor, ligament, tänder, hud m.m. Bindväven utgör kroppens stomme och bidrar med stödjande och elastiska funktioner samt ger skydd åt kroppen både på utsidan och åt de inre organen. Det finns ganska få celler i bindväv jämfört med många andra vävnader i kroppen och det finns olika celltyper i olika sortThe properties of different connective tissues depend on the synthesis and assembly of macromolecular structures composed of collagen and other extracellular matrix components. Mechanisms modulating these events play important roles in the formation of a functional tissue. We have studied the role of collagen-binding extracellular matrix leucine-rich repeat glycoproteins/proteoglycans in the forma

On Axioms Underlying Use of Reserve Price

This paper establishes reserve price as an ethical necessity contrary to its popular interpretation as an instrument of revenue maximization. It provides an axiomatic justification to reserve pricing at Vickrey auction in single as well as multiple objects settings. In particular, it provides a topological interpretation of a reserve price as the infimum of the set of non-negative real numbers sat

Chronic Arthritis in Rats; Pathogenesis and genetic factors

Popular Abstract in Swedish Ärfltiga faktorer orsakar ledgångsreumatism Reumatoid artrit (RA) även kallat ledgångsreumatism är en ledsjukdom som drabbar 1% av befolkningen, framförallt kvinnor. Orsaken till sjukdommen är inte känd, men man tror att det finns en ärftlig faktor som avgör om en viss individ kan utveckla reumatoid artrit eller inte. Den genetiskassociationen man idag vet om är till m

Theoretical Studies of Binaries in Astrophysics

Popular Abstract in Swedish Jag har i den här avhandlingen behandlat problemställningar inom tre olika områden inom astronomin. Det som sammanlänkar dessa är att alla innefattar dubbelstjärnor där avståndet mellan stjärnorna är litet, dvs de har en kort period. De är också alla datorsimuleringar. Jag har satt upp en modell för att betrakta de astronomiska systemen och genom numeriska metoder beräkThis thesis introduces and summarizes four papers dealing with computer simulations of astrophysical processes involving binaries. The first part gives the rational and theoretical background to these papers. In paper I and II a statistical approach to studying eclipsing binaries is described. By using population synthesis models for binaries the probabilities for eclipses are calculated for diff

Om regelkonkurrens inom inkomstskatterätten. Med särskild inriktning på förhållandet mellan olika grunder för beskattning av dolda vinstöverföringar till utlandet.

Popular Abstract in Swedish Bland kommunalskattelagens (KL) allmänna bestämmelser finns vissa regler som motverkar överföringar av obeskattade vinstmedel mellan företag. Om ett företag säljer en tillgång eller tjänst för ett pris understigande marknadsvärdet kan uttagsbeskattning ske. Om ett företag i stället köper en tillgång eller tjänst för ett pris överstigande marknadsvärdet är det möjligt atThis dissertation deals with the conflict of rules for the taxation of income. By 'conflict of rules' I refer to the circumstance that two or more provisions are applicable simultaneously, but where it is clear that only one of the provisions concerned could or should be applied. The dissertation concentrates on the relationship between the different provisions - within the Swedish legal system -

Outcome measures in haemophilia: a systematic review

Haemophilia A and B are hereditary X-linked disorders due to deficiency (or absence) of coagulation factor VIII or IX, respectively. Bleeding risk is related to the severity of factor deficiency. Repeated joint bleeding can lead to a severe haemophilic arthropathy resulting in disabilities. Outcome measurements in persons with haemophilia (PWH) have been limited to laboratory evaluation (factor VI