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Background: Severe inflammatory airway diseases are associated with inflammation that does not resolve, leading to structural changes and an overall environment primed for exacerbations. Objective: We sought to identify and inhibit pathways that perpetuate this heightened inflammatory state because this could lead to therapies that allow for a more quiescent lung that is less predisposed to sympto

Aim: Attention-deficit/hyperactivity disorder (ADHD) is the most common diagnosis within child- and adolescent psychiatry. Waiting lists and delayed care are major issues. The aim was to evaluate if standardized care (SC) for assessment and treatment of uncomplicated ADHD would reduce resource utilization and increase satisfaction with preserved improvement within the first year of treatment. Meth

Restraint stresses appear in structural parts which are prevented from adjusting their shape when subjected to e.g. shrinkage or thermal actions. If the restrained stresses are large, cracking might occur, which can affect the durability of the structure. In the case of restraint effects, the reinforcement required in a bridge to limit the crack widths can be difficult to determine, as the magnitu

The complement system plays an important role in varying types of disease, ranging from inflammatory and autoimmune disorders to immune deficiency states. In addition, new settings have emerged where complement analysis is of interest to monitor complement-directed therapy and aid identification of transplant complications. Therefore, it is critical that clinical laboratories offer optimized and t

Massively parallel sequencing (MPS) methods are increasingly applied in forensic casework. However, adequate validation guidelines are lacking. In this work, we describe our in-house validation of the ForenSeq DNA Signature Prep Kit (Verogen) for analysis of ancestry- and phenotype-informative SNPs. We also discuss in-house validation of MPS assays in general terms. When validating the SNP assay,

A new approach for one‐stage facile membrane modification during non‐solvent induced phase separation (NIPS)‐process is proposed. The novelty of this study is that cheap and commercially available anionic high molecular polyacrylamide‐based flocculant (AHMPF) is applied for the first time as an additive to coagulation bath (CB). The series of polyethersulfone membranes were prepared using 0.05–0.3

Artikeln kompletterar två tidigare texter i tidskriften Ale 2020: 2–3 om Lyngsjö i Skåne. Elisabeth Reuterswärd söker här bakgrunden till dopfuntens ovanliga motiv, medan Sten Skansjö förklarar utvecklingen i socknen över tid. Denna artikel uppmärksammar, att dopfunten har spår av bemålning, kommenterar kyrkans herrskapsgalleri, korrigerar upplysningarna om antalet gyllene altare i Norden, visar aThe article presents a supplement to two earlier texts in the periodical Ale 2020: 2–3 on Lyngsjö in Scania. Elisabeth Reuterswärd here seeks the background for the unusual motif of the baptismal font, where Sten Skansjö tries to explain the development in the parish over time. The present article draws attention to the fact that the font has traces of painting, comments on the upper gallery of th