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Tool Coating is a method for enhancing cutting efficiency and extending tool life, essential for machining hard materials. While Polycrystalline Cubic Boron Nitride (PcBN) tools are already well-suited for harsh machining conditions, their durability can be further improved with coatings. However, as the machining operation continues, tool coating loss occurs, reducing the durability of the tool a
OBJECTIVE: To explore changes in health-related quality of life (HRQoL) measured using EQ-5D-5L among participants of a digital education and exercise therapy for knee and hip osteoarthritis (OA).METHODS: A descriptive longitudinal registry-based study among participants aged 40 + years enrolled in the digital program with responses to EQ-5D-5L at enrolment and at least one follow-up at 3- [n = 15
In hard milling operations under severe conditions, polycrystalline cubic boron nitride (PcBN) tools are commonly used. Monitoring their degradation in real time is important to maintain process stability and to reduce tool costs. To use accelerometer data sampled with relatively low sampling frequency enables efficient data collection and analysis. However, the high noise levels in machining requ
Fused Filament Fabrication (FFF) is an additive manufacturing process based on Material Extrusion (MEX) of polymeric filament. This manufacturing technology is commonly used for personalized production applications and prototyping, allowing to obtain customized parts with complex geometries at a low cost. However, this production technique has its limitations regarding dimensional accuracy and sur
A string of speech is a string of syllables, a series of varying amounts of jaw openings/closings. Neutralizing the vowel-intrinsic jaw opening indicates a pattern of jaw opening matching the utterance syllable prominence patterns. The hypothesis is that the jaw-opening patterns ensue from the metrical hierarchy of the language, such that for languages such as English, we see exponentially increas
Prostate cancer remains one of the most prevalent malignancies in men worldwide, and early detection, accurate characterization, and staging are critical for optimal patient management. Diffusion magnetic resonance imaging (dMRI) has emerged as a powerful technique for non-invasive in vivo imaging of tissue microstructure, promising to enable unprecedented insights into the pathophysiology of pros
The ZUC stream cipher is integral to modern mobile communication standards, including 4G and 5G, providing secure data transmission across global networks. Recently, Dutta et al. (Indocrypt, 2024) presented the first quantum resource estimation of ZUC under Grover’s search, although preliminary, this work marks the beginning of quantum security analysis for ZUC. In this paper, we present an improv
Small and medium-sized enterprises are important contributors to economic development and employment in lower middle-income countries (LMICs), yet their capacity to innovate remains constrained by institutional fragility, resource scarcity, institutional weaknesses, and fragmented innovation systems. These challenges are particularly pronounced in Bolivia. Despite growing recognition of business m
Retinopathy of prematurity (ROP) is a neurovascular retinal disease affecting extremely preterm infants (<28 weeks' gestational age), and links between early lipid metabolism and ROP are unclear. We investigated whether the lipid mediator sphingosine-1-phosphate (S1P) and its carrier apolipoprotein M (ApoM) are associated with ROP and parenteral nutrition in preterm infants. In this multicenter co
Analysis of signals defined on complex topologies modeled by graphs is a topic of increasing interest. Signal decomposition plays a crucial role in the representation and processing of such information, in particular, to process graph signals based on notions of scale (e.g., coarse to fine). The graph spectrum is more irregular than for conventional domains; i.e., it is influenced by graph topolog
The work in this thesis investigates land-atmosphere exchange of carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) in a semi-arid savanna of the African Sahel. Despite the importance of drylands for the global carbon cycle, substantial uncertainties remain regarding their overall greenhouse gas (GHG) exchange, with particular scarcity of observations in Africa. The aim wasto quantify tem
Mitochondrial diseases are clinically and genetically heterogeneous, often complicating diagnosis. Here, we describe four unrelated individuals with suspected mitochondrial disease who shared similar neuroimaging features, including bilateral symmetrical supra- and infratentorial white-matter abnormalities, together with variable movement disorders and intellectual impairment. Whole-genome sequenc
Innovation in resource-constrained environments is often limited not only by scarce financial and technological resources but also by weak institutional support and misalignment between the capabilities of knowledge-producing organizations and the conditions under which local actors can adopt, adapt, and sustain innovation. Although Design Thinking has been widely studied as a human-centred innova
Introduction: In aortic valve disease, several interventions are available. In young people who are still growing, or considering the risks of long-term anticoagulation, the Ross procedure remains an alternative for aortic valve replacement. This procedure entails the transposition of the patient’s pulmonary valve to the aortic position, with placement of a homograft in the pulmonary position. How
Purpose of review – Oxygen therapy is a key component of interstitial lung disease (ILD) management. This review summarizes the current evidence and explores how to balance its benefits and burdens in people with ILD. Recent findings – Hypoxemia frequently occurs in ILD and is associated with worse prognosis, but the extent to which oxygen therapy modifies outcomes remains uncertain. Observational
This study investigates the role of structural similarity in third language acquisition by using two different semi-artificial languages (ALs, called Aliensk A and Aliensk N) as the targets and either Polish–Norwegian or Norwegian as the previously acquired languages (all speakers also know English). It is an extension of Mitrofanova et al., who did a similar study with one semi-artificial languag
