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Fine-needle aspiration cytology of soft tissue sarcoma: benefits and limitations.

Purpose. Examine the benefits and limitations of fine-needle aspiration cytology (FNA) used as the definitive diagnostic method before treatment.Method. Review of the 25 year experience at a multidisciplinary musculo-skeletal centre where FNA is the primary diagnostic approach to soft tissue sarcoma in the extremities and trunk wall and the experience of various experts in the field.Results. FNA h

Performance of Reduced-Complexity Transmit/Receive-Diversity Systems

We consider wireless systems with maximal-to the different transmit antennas are weighted replicas of ratio combining diversity at the base station, and hybrid selection/maximal ratio combining at the mobile station. We have recently proposed these systems, which provide high-quality data links, while keeping the complexity at the mobile station low. We analyze their performance in various realist

Toll-Like Receptor 4 Promoter Polymorphisms: Common TLR4 Variants May Protect against Severe Urinary Tract Infection.

BACKGROUND: Polymorphisms affecting Toll-like receptor (TLR) structure appear to be rare, as would be expected due to their essential coordinator role in innate immunity. Here, we assess variation in TLR4 expression, rather than structure, as a mechanism to diversify innate immune responses. METHODOLOGY/PRINCIPAL FINDINGS: We sequenced the TLR4 promoter (4,3 kb) in Swedish blood donors. Since TLR4

Primary HIV-1 R5 isolates from end-stage disease display enhanced viral fitness in parallel with increased gp120 net charge.

To better understand the evolution of the viral envelope glycoproteins (Env) in HIV-1 infected individuals who progress to AIDS maintaining an exclusive CCR5-using (R5) virus population, we cloned and sequenced the env gene of longitudinally obtained primary isolates. A shift in the electrostatic potential towards an increased net positive charge was revealed in gp120 of end-stage viruses. Residue

Regional Innovation System Policy: a Knowledge-based Approach

A focus on constructing regional advantage requires an unpacking of what makes territorial agglomerations important for innovation and growth by disclosing and revealing the contingencies, particularities and specificities of the various contexts and environments where knowledge creation, innovation and entrepreneurship take place. In order to achieve more effective regional innovation policy, the

Vad är rätt? Juridiska och etiska frågor i Certecs vardag

Vardagsarbetet på Certec tangerar ofta etiska och juridiska spörsmål. Detta är mer av godo än av ondo. Det är viktigt för en verksamhet, som bedrivs nära människor, att det etiska samtalet hålls levande, och att frågor ständigt väcks kring vad som kanske rent av är reglerat i lag. Funderingarna och samtalen handlar inte bara om vad som kan vara olagligt eller oetiskt att göra – minst lika ofta gäl