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Environmental relative humidity (RH) and temperature (T) are known to be promoters of physicochemical changes in pharmaceutical grade lactose, either in controlled (supervised conditioning), or uncontrolled (during transit and repository storage) scenarios. Comprehensive knowledge of this excipient's material characteristics prior to its use in formulation development is therefore a fundamental re

BackgroundWireless pH-monitoring is an accurate method for diagnosing adults with gastroesophageal reflux disease (GERD). The aim of this study was to evaluate the use of the Bravo capsule on children investigated for GERD in terms of safety, tolerability and feasibility before and after administration of proton pump inhibitors.MethodsA Bravo capsule was inserted during upper endoscopy under gener

ObjectivesOur aim was to study the association between residential land cover and greenness during childhood and risk of developing celiac disease (CeD).MethodsThe Celiac Prediction in Skåne study prospectively followed 5969 human leukocyte antigen (HLA)-genotyped children born 2001–2004 who were screened for CeD at ages 3, 9, and 15 years in Skåne, Sweden. Among these, 138 (2.3%) children only in

Although intermarriage is a commonly used indicator of immigrant integration into host societies, most research has focused on how individual characteristics determine intermarriage. This study uses the 1-910 IPUMS census sample to analyze how contextual factors affected intermarriage among European immigrants in the United States. We use newly-available complete-count census mircodata to construc

Biobased polyesters are emerging as sustainable alternatives for hot-melt adhesives (HMAs) owing to their tunable adhesion properties, facile processing, and versatile end-of-life options. Here, we report on the design of low-temperature (100 °C) HMAs, derived from oxygen-rich lignin-based copolyesters synthesized via copolymerization of a syringic acid-derived aromatic monomer with biobased aliph

In an era of global migration, where public discourse often assumes that migrants lack exposure to and command of local majority language(s), it is a crucial research task to understand how migrants learn and use new languages in their everyday lives. This study provides empirical evidence about the quantity and nature of everyday language exposure and use (LEU) among migrants in Sweden. Using the

Collaborative governance networks are increasingly central to local climate action, yet research offers limited understanding of the personal, psychological, and informal factors that sustain engagement within them. This paper examines how such networks facilitate meaningful and lasting participation through an in-depth study of Malmö Works, a long-standing public–private collaboration focused on

The negative relationship between birth interval length and neonatal mortality risks is well-documented, but the possibility of heterogeneity in this relationship has been largely ignored. Understanding variation in the strength of this relationship may be important for adjusting family planning programs strategies for issues regarding fertility regulation and maternal and child health, however, a

Introduction: Evidence for gut–kidney interactions in early kidney disease is limited, particularly in community-dwelling adults with largely preserved kidney function. Here, we quantified links between gut microbiota and estimated glomerular filtration rate (eGFR) in two population-based Swedish cohorts. Methods: Deep shotgun metagenomics profiled fecal samples from 9788 adults in the Swedish CAr

We find that CO ligates selectively to nitrogen tetra-coordinated Co(i) single metal atom sites at room temperature in a manganese–cobalt bi-metallic coordination network self-assembled on graphene. The bound state is metastable, determined by pressure-dependent equilibrium conditions between adsorption and desorption, with an upright, end-on bonding geometry (binding energy 0.73 eV). The ligand v

This paper examines income and employment outcomes for immigrants in Sweden’smost immigrant-dense neighbourhoods between 1998 and 2022. While relativeemployment among immigrants has improved, relative incomes in theseneighbourhoods have stagnated or declined. The most plausible explanation for thepersisting income gap and the shrinking employment gap between immigrant-dense and other neighbourhood

Ion clustering has been proposed as a mechanism leading to the peculiar "anomalous underscreening" phenomenon seen for electrostatic interactions between charged surfaces immersed in concentrated electrolytes. These interactions have been measured using the Surface Force Apparatus, according to which there are strong repulsive interactions between like-charged surfaces, with a range that increases

Introduction: Consensus is lacking regarding the upper limit for a safe contraction frequency during labor. We aimed to assess the association between different contraction frequencies and acidemia at birth, and whether an association was affected by oxytocin augmentation, concomitant cardiotocography (CTG) classification, and stage of labor. Material and Methods: This is a case–control study base

Aging is accompanied by progressive physiological declines in body functions. However, the molecular mechanisms of aging remain poorly understood in decapod crustaceans, a diverse group of invertebrates. We investigated age-related differences in the hemolymph proteomes of marbled crayfish using label-free protein quantification (LC-MS/MS), applying a significance threshold of p < 0.05 and a fold

We investigated dynamic changes in nicotinamide adenine dinucleotide (NAD+) metabolism in the human occipital lobe using ultra-high field 31P functional magnetic resonance spectroscopy (fMRS) at 7 T. Twenty-five healthy volunteers (mean age 24 ± 4 years, 10 females) performed a visual task alternating between fixation and flashing checkerboard stimuli. 31P MRS spectra were acquired from a visual c

We derive an explicit link between Gaussian Markov random fields on metric graphs and graphical models, and in particular show that a Markov random field restricted to the vertices of the graph is, under mild regularity conditions, a Gaussian graphical model. This graphical model has a distribution which is faithful to its pairwise independence graph, that coincides with the neighbor structure of

Drawing on a playful notebook entry from Hans Jonas’s student years, this article examines why Jonas consistently sidestepped Friedrich Schelling’s Naturphilosophie in his writings on philosophical biology. It begins by outlining the many affinities between the two thinkers, as noted in previous scholarship: both articulate an asubjective teleology, both understand or­ganisms as self-individuating