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Background: Anastomotic leakage is a serious complication following anterior resection for rectal cancer and may increase the risk of long-term bowel dysfunction. This study aimed to assess the long-term impact of anastomotic leakage on major low anterior resection syndrome (major LARS) at a uniform follow-up time. Methods: We conducted a nationwide cohort study using the Swedish Colorectal Cancer

This document summarizes the discussions and outcomes of the Facility for Rare Isotope Beams (FRIB) Theory Alliance topical program ‘The path to Superheavy Isotopes’ held in June 2024 at FRIB. Its content is non-exhaustive, reflecting topics chosen and discussed by the participants. The program aimed to assess the current status of theory in superheavy nuclei (SHN) research and identify necessary

Ideellt engagemang utgör en central del av det svenska förenings- och studentlivet, där många studenter lägger betydande tid och energi på oavlönat arbete vid sidan av sina studier. Trots avsaknaden av ekonomisk ersättning fortsätter detta engagemang att vara både omfattande och långvarigt, vilket väcker frågor om vilka faktorer som driver studenter att engagera sig och vad som gör att engagemangeVoluntary engagement is a central aspect of Swedish student life, where many students invest significant time and energy in unpaid work alongside their studies. Despite the absence of financial compensation, such engagement remains both extensive and long-lasting. We aim to answer questions such as, what motivates students to participate and what factors contribute to sustaining their involvement

I ett litet skånskt vattendrag hittades förhöjda halter av så kallade ”evighetskemikalier” som kan innebära risker för livet under ytan. Trots att vattnet ser rent ut visar mätningar att påverkan från industri och avloppsvatten är större än vad man tidigare känt till. PFAS är en stor grupp industrikemikalier med mycket goda vatten-, fett- och smutsavvisande egenskaper samt hög kemisk- och värmestFreshwater ecosystems are increasingly threatened by persistent chemical pollutants, including per- and polyfluoroalkyl substances (PFAS), which pose long-term risks to both ecosystems and human health. Small streams downstream of urban and industrial areas are often underrepresented in monitoring programmes, despite their potential vulnerability to PFAS contamination. Furthermore, environmental r

In the present study, the novel family genetic risk score (FGRS) method, a reliable quantification of latent genetic risk, was applied to posttraumatic stress disorder (PTSD) to examine associations between genetic liability and clinical features of PTSD among 3,097,180 individuals in the Swedish national registries. FGRS was calculated based on lifetime PTSD status for first- through fifth-degree

The integration of Proton Exchange Membrane electrolyzers into hydrogen generation systems offers significant potential for sustainable energy solutions. Integrating hydrogen production with electricity, heat, and renewable energy sources enhances sustainability. PEM electrolyzers effectively address renewable energy intermittent by converting energy into hydrogen, leveraging their ramp rate and l

Wide-angle neutron scattering analysed using empirical potential structure refinement (EPSR) was used to investigate how aromatic ring structure influences micelle self-assembly in two anionic surfactants: sodium 4-heptylbenzene sulfonate (SHBS) and sodium 5-heptylfuran-2-sulfonate (SHFS). Both surfactants formed globular micelles in aqueous solutions at 0.2 M but differed significantly in micelle

Wildfires, insect outbreaks, and storms cause large pulses of tree mortality. Climate change amplifies these forest disturbances, yet their future magnitude and extent remain uncertain. Here, we simulated future forest disturbance regimes at 100-meter resolution across Europe using a deep learning–based simulation framework. Our results show that forest disturbances will continue to increase throu

Loss of genetic diversity threatens species survival, yet its dynamics and impacts can vary widely across species depending on their evolutionary histories, life-history traits, and demographic trajectories. To investigate these differences, we analyzed the genomes of 3 species that experienced extreme and well-documented population bottlenecks, the Mauritius parakeet, the Mauritius kestrel, and t

Introduction: Synovial fibroblasts (S-Fib) are recognized as key drivers of joint inflammation in adult arthritis. Moreover, data are limited on the processes driving monocyte activation in oligoarticular juvenile idiopathic arthritis (oJIA). Therefore, we aimed to explore if S-Fib from patients with oJIA induce monocyte activation. Methods: S-Fib were isolated from the synovial fluid (SF) of n =

In recent years, Predictive Digital Twins (PDT) have emerged as a potential tool to monitor and predict the behavior of dynamic systems, including nature-based solutions in natural coastal systems. Here, we test the potential of using a simple, coupled shoreline and beach-dune model as a base for a PDT. The models exchange sediment flux balance information at each time step and recalculate shoreli

OBJECTIVE: To assess structural changes at peripheral entheses and the association with spinal bone formation in patients with long-standing radiographic axial spondyloarthritis (r-axSpA) overall and stratified by sex. METHODS: Peripheral entheses were examined cross-sectionally using ultrasound (US) in patients fulfilling the modified New York criteria for ankylosing spondylitis (AS) and assessed

We present a genome assembly from a male specimen of Zethes insularis (Arthropoda; Insecta; Lepidoptera; Erebidae). The assembly contains two haplotypes with total lengths of 862.07 megabases and 869.20 megabases. Most of haplotype 1 (99.0%) is scaffolded into 31 chromosomal pseudomolecules, including the Z sex chromosome. Most of haplotype 2 (95.76%) is scaffolded into 31 chromosomal pseudomolecu

Urban areas are increasingly exposed to extreme precipitation events, which can disrupt critical infrastructure and damage the built environment. While flood impacts are often assessed separately for buildings or road networks, this study analyses both flood-induced road inaccessibility and building flood risk in Gothenburg using a climate-adjusted 100-year rainfall at both the city scale and the