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Introduction: Adolescents are increasingly exposed to hate speech in both online and offline contexts, yet limited research has examined how such exposure is experienced and how it relates to adolescents' psychological needs and well-being. Drawing on Self-Determination Theory (SDT), this study explores how adolescents make sense of hate speech and how these experiences affect autonomy, competence
Wind energy is an important form of clean energy, and its rational utilization represents a crucial solution for mitigating the energy crisis and global warming. In this study, wind energy potential and its long-term changes in the South China Sea (SCS) are evaluated using ERA5 100 m wind data from 1944 to 2023, validated against ASCAT observations. High wind speeds and high wind power density (WP
More than 70% of climate policies target low-carbon technologies, with hopes that policy support will trigger tipping points and self-reinforcing growth. In practice, however, trajectories of policy-driven technologies remain difficult to explain and anticipate because their growth is nonlinear and often constrained by backlash, policy reversals and systemic barriers. In this Perspective, we devel
Musculoskeletal health is essential to health, well-being, and independence across the life course. Musculoskeletal conditions including inflammatory joint diseases, osteoarthritis, back pain, osteoporosis, and fragility fractures are among the greatest causes of disability globally imposing a major burden on health and social care and economic impact also through lost productivity. Despite effect
Background:Support, Monitoring, and Reminder Technology for Mild Dementia (SMART4MD), a customized tablet app, was developed to improve or maintain the quality of life of people with mild cognitive impairment (MCI) and their informal caregivers.Objective:This study conducts an 18-month economic evaluation of the SMART4MD app, in addition to standard care, compared with standard care alone in Swede
Does the human animal have an exclusive access to the realm of religious devo-tion? While both scholars and scientists are beginning to speak of and recognizeagency among nonhuman species, we have yet to explore the field of nonhumanreligiosity. The following article takes a first step in this direction by exploringhow especially Ambrose of Milan, in his Hexaemeron sermons, ascribed religiousagenc
Abstract in FrenchL’architecture éminente scandinave à la fin du Moyen-Âge sur terre et en mer. Une étude spatiale du château de Glimmingehus et du navire de guerre Gribshunden Par MARTIN HANSSON et BRENDAN FOLEYCe papier compare l’utilisation sociale de l’espace dans les châteaux et les navires de guerre à la fin du Moyen-Âge. Les principales études de cas utilisées sont le château de GlimmingehuTHIS PAPER COMPARES THE SOCIAL USE OF SPACE in late-medieval castles and warships. The main case studies used are the noble castle of Glimmingehus in present-day Sweden, built 1499 to 1505, and the royal warship Gribshunden, in use from the mid-1480s until its sinking in 1495; we also refer to the later and fully excavated warships Mary Rose and Vasa. Both castles and warships are examples of elit
The proline-rich domain (PRD) of the tumor suppressor p53 plays a central role in modulating conformational dynamics and molecular interactions, yet its intrinsic structural behavior remains incompletely understood. Here, we combine extensive all-atom molecular dynamics simulations with biophysical validation to characterize the conformational ensemble of the p53 PRD. The domain behaves as an intr
OBJECTIVE: To evaluate the association between metformin use and incident osteoarthritis (OA) in people with diabetes and the impact of dosing. DESIGN: Nested case-control study within a cohort of >1.4 million individuals from Sweden. PARTICIPANTS: Participants were aged 35-80 years in 2005, without diabetes or OA. We identified persons with incident diabetes between 2006 and 2016 and excluded tho
Immunoglobulin G subclass deficiencies (IgGSD) are associated with recurrent respiratory tract infections. Tools to identify patients with IgGSD who benefit from immunoglobulin G replacement therapy (IgGRT) are lacking. This crossover study evaluated the number of antibiotic-demanding infections on and after up to 18 mo off IgGRT in 28 patients with IgGSD. Pneumococcal antibodies against 21 seroty
This chapter explores the links between climate change, environmental degradation, and protracted armed conflicts, focusing on how international law can facilitate effective environmental interventions. It examines how international law, particularly the work of the UN International Law Commission on the Protection of the Environment in relation to Armed Conflicts (PERAC) Principles, international
Introduction: Ultra-severe traumatic brain injury (us-TBI), defined as Glasgow Coma Scale score (GCS) of five-three, is associated with high mortality and severe morbidity amongst survivors. However, in selected patients a favourable recovery may still be achieved. Research question: We aimed to characterise what clinical parameters can be used as prognosticators in us-TBI patients. Material and m
AIMS: To investigate the prevalence of diastolic dysfunction and associated risk factors in pre-diabetes and diabetes in the general population.METHODS: Diastolic function was assessed by transthoracic echocardiography in a cross-sectional sample of 3840 men and women aged 50-64 years from the Swedish CArdioPulmonary bioImage Study. Anthropometry, medical history, blood pressure, biochemistry and
Background: Photon-counting computed tomography (PCCT) is an emerging technique under evaluation for temporal bone imaging. Its capacity for radiation dose reduction while maintaining diagnostic image quality (IQ) requires further study. Purpose: To evaluate how PCCT compares to energy-integrating CT (EICT) in temporal bone imaging in terms of IQ and visualization of anatomical landmarks, at a cli
