Sökresultat

Understanding how genetic polymer sequences became coupled with the reproduction of protocellular compartments is a fundamental challenge in the study of the emergence of living systems. Here, we demonstrate that the coexistence of peptides with defined amino acid sequences and fatty acid vesicles can establish a primitive form of this coupling. We prepared systematically sequence-controlled pepti

Background and Aim: This study aims to identify if and how Industry 5.0 technologies support achieving SDG-2 in relation to agri-food supply chains. There is need for this research as the deadline for achieving the SDGs looms large in 2030, and progress toward the SDG-2 targets has been unsatisfactory.Research Design and Methods: This research employs an agri-food supply chain-oriented approach to

Under 14 år har Europarådets styrkommitté för mänskliga rättigheter inom biomedicin och hälsa (CDBIO) arbetat med ett nytt tilläggsprotokoll till Konventionen om mänskliga rättigheter och biomedicin (Oviedokonventionen). Protokollet gäller skyddet för mänskliga rättigheter och människovärde vid psykiatrisk vård utan samtycke. Arbetet har varit omstritt och i januari 2026 tog striden ännu en vändni

The analysis, control, and design of complex networks and systems represent an essential and ever-expanding field of study. At its foundation lie mathematical models that capture complex physical phenomena while remaining amenable to both analysis and design. These models prove instrumental in representing diverse systems such as power grids, cellular telecommunication networks, large-scale manufa

Inland water CO2 emissions are a critical component of the global carbon cycle, yet their magnitude and long-term response to climate change remain poorly constrained, primarily because of uncertainties in the air–water CO2 concentration gradient. This knowledge gap is particularly pronounced on the Tibetan Plateau, where thin air and exceptional climate sensitivity complicate accurate quantificat

This article examines the role of tourism in the development of nature-based solutions and urban green infrastructure, with particular attention to biodiversity enhancement and ecosystem service co-production. Research has explored relationships between rural tourism and biodiversity, but relations between tourism, biodiversity, and nature-based solutions in urban areas remain underdeveloped. The

Cooling clothing is a personal cooling system that only cools the microclimate around an individual, alleviating heat stress. This study used a progressive heat stress protocol (PHSP) to evaluate the cooling effectiveness of a liquid cooling vest (LCV), a type of cooling clothing. Through the PHSP, the upper-limit thermal environment for the physiological prescriptive zone was determined for both

The concept of ‘imaginaries’ has gained prominence as a lens for examining how collective orientations shape social and organisational action; yet the meaning of this concept and its relation to neighbouring notions has become so diffuse as to call into question its analytical potential. Addressing this need for clarification, we situate imaginaries within a genealogy of imagination, tracing the cThe concept of ‘imaginaries’ has gained prominence as a lens for examining how collective orientations shape social and organisational action; yet the meaning of this concept and its relation to neighbouring notions has become so diffuse as to call into question its analytical potential. Addressing this need for clarification, we situate imaginaries within a genealogy of imagination, tracing the c

This article is an introduction to a special issue of the journal ‘Interface Focus’ dedicated to Professor Stephen T. Hyde on the occasion of his retirement. Professor Hyde’s scientific career has revolved around using the geometric study of structures with negative Euler index (Formula presented)—bicontinuous and other negatively curved surfaces, spatial nets, tangles and knots—to understand the

We have compared the performance of 64 different computational methods, based on combined quantum mechanical (QM) and molecular mechanical (QM/MM) or QM-cluster calculations in a continuum solvent, to estimate the acid constant (pKa) of metal-bound ligands in proteins. As a calibration set, we use 12 experimental pKa values from six different proteins that involve Zn2+, Fe3+, or Fe4+. We employ tw

Background: Heart failure (HF) is a common disease among older individuals and is associated with poor quality of life and prognosis. Individuals at risk of developing HF are usually already patients in primary healthcare, but diagnosing HF at an early stage can be challenging. Identifying patients at risk of HF and initiating early treatment is crucial for their outcomes. Using the variables gend

This study theoretically evaluates the detection time window for assessing internal dose following the inhalation of radionuclides released in a postulated accident scenario at the European Spallation Source (ESS). The assessment focuses on gamma-emitting radionuclides and investigates the feasibility of high-resolution whole-body counting (WBC) and gamma spectrometric analysis of 24-h urinary exc

In this paper, we consider integral linear constraints and the dissipation inequality with linear supply rates for certain sets of trajectories confined pointwise in time to a convex cone which belongs to a finite-dimensional normed vector space. Such constraints are then shown to be satisfied if and only if a bounded linear functional exists which satisfies a conic inequality. This is analogous t

OBJECTIVES: To explore and map the literature on referral pathway gaps and improvement strategies in primary healthcare (PHC) to secondary healthcare (SHC) referrals, and to categorise both gaps and improvements using the Quintuple Aim framework for healthcare improvement-a model encompassing patient experience, population health, costs, provider well-being and health equity. DESIGN: Scoping revie