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Breast cancer exhibits significant molecular, pathological, and clinical heterogeneity. Current clinicopathological evaluation is imperfect for predicting outcome, which results in overtreatment for many patients, and for others, leads to death from recurrent disease. Therefore, additional criteria are needed to better personalize care and maximize treatment effectiveness and survival.
Discussion of Zhang Yimou's film Coming Home.
I såväl media som inom myndigheter och organisationer har det under de senaste åren i allt högre grad uppmärksammats att migrerande arbetskraft inom jordbruket/den gröna näringen eventuellt används på ett sätt som kan strida mot arbetsrättsliga och sociala regleringar.Avsikten med föreliggande studie är framförallt att sammanställa den forskning som finns avseende olika arbetslivs- och arbetsmiljö
The literature data on the region at about 55-60 at.% Cu in the Cu-In phase diagram is somewhat confusing. With Cu10In7 and Cu11In9, two intermetallic compounds have been reported whose structures are alike and both are reported to be stable over a similar temperature range. Here, we show that Cu10In7 can be synthesized and characterized in agreement with the study by Piao and Lidin. Moreover, the
We study the induced subgraph isomorphism problem and the general subgraph isomorphism problem for small pattern graphs. We present a new general method for detecting induced subgraphs of a host graph isomorphic to a fixed pattern graph by reduction to polynomial testing for nonidentity with zero over a field of finite characteristic. It yields new upper time bounds for several pattern graphs on f
Organotypic spinal cord slices from neonatal mammals could be a powerful model for evaluation of cell survival but also cell death mechanisms. The aim of this study was to establish an in vitro model for investigating cell survival and mechanism involved in cell death in neonatal spinal cord slices. The spinal cord was sliced and incubated into culture medium. The MTT assay was carried out to asse
Background: Food consumption is one of the most important drivers of environmental pressures. Adoption of healthy diets is suggested to be an option for less environmentally intensive food habits and improved public health. In particular, changes in meat consumption are believed to bring potential benefits. Objective: To quantify the impact of changes in meat consumption on the dietary contributio
In this paper, we address the problem of locating a target using multiple-input multiple-output (MIMO) radar with widely separated antennas. Through linearizing the bistatic range measurements, which correspond to the sum of transmitter-to-target and target-to-receiver distances, a quadratically constrained quadratic program (QCQP) for target localization is formulated. The solution of the QCQP is
In this work, we demonstrate how a lateral motion of a supported lipid bilayer (SLB) and its constituents can be created without relying on self-spreading forces. The force driving the SLB is instead a viscous shear force arising from a pressure-driven bulk flow acting on the SLB that is formed on a glass wall inside a microfluidic channel. In contrast to self-spreading bilayers, this method allow
Background: We found marked improvement of glycemic control and several cardiovascular risk factors in patients with type 2 diabetes given advice to follow a Paleolithic diet, as compared to a diabetes diet. We now report findings on subjective ratings of satiety at meal times and participants' other experiences of the two diets from the same study. Methods: In a randomized cross-over study, 13 pa
Accurately predicting binding affinities between ligands and macromolecules has been a much sought-after goal. A tremendous amount of resources can be saved in the pharmaceutical industry through accurate binding-affinity prediction and hence correct decision-making for the drug discovery processes. Owing to the structural complexity of macromolecules, one of the issues in binding affinity predict
Integrated Water Resources Management (IWRM) is a relatively new approach in Bolivia. However, it is now generally accepted that this approach needs to be established in order to find sustainable solutions for development and is actively promoted by the Water Ministry, especially in environmentally fragile regions, such as the Lake Poopo basin. The Lake Poopo basin is one of the poorest regions in
Artikeln belyser hur kristna antijudiska stereotyper genljuder i sekulariserad form i delar av nutida politisk filosofi.
Immune cells within the tumor can act either to promote growth or rejection of tumor cells. The aim of the present study was to evaluate immune cell markers (number and localization) within the tumor before and during rejection due to radioimmunotherapy, to determine whether there is a change in markers related to rejection and/or tolerance of the tumor cells.
Specific inhibition of the entry of encephalitogenic T lymphocytes into the central nervous system in multiple sclerosis would provide a means of inhibiting disease without compromising innate immune responses. We show here that targeting lymphocyte interactions with endothelial basement membrane laminins provides such a possibility. In mouse experimental autoimmune encephalomyelitis, T lymphocyte
Popular Abstract in Swedish Avhandlingens ämne är monstrets roll i människans försök att definiera sig själv – hur kroppar som kan benämnas ”monstruösa” fungerar som naturfilosofiska figurer i humanismens strävan att avgränsa det mänskliga från det omänskliga. Studien spänner över perioden från renässansen eller den tidigmoderna eran till postmoderniteten men fokuserar den franska miljön och två gThis dissertation studies the problem of the inhuman in relation to human nature in philosophy from antiquity to the present, highlighting the interrelationship between science and philosophy in the development of concepts of monstrosity in France from mid-sixteenth century to late twentieth century thought. By means of constraint, it focuses on Ambroise Paré (1509/10–90) and Gilles Deleuze (1925–
