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Background: Complementary prognostic markers are needed in thymic epithelial tumors (TETs) to aid patient stratification and determine the most appropriate follow-up strategies. This study aimed to assess the diagnostic and prognostic relevance of blood-based inflammatory markers in a large cohort of surgically treated TET patients. Material and Methods: A total of 743 TET patients who underwent s
Rhythmic patterning is a widespread structural trait of animal (including human) communication. Concomitantly, a key role of communication is to convey and/or induce emotion. The expression and modulation of emotion is also hypothesized to be a key mechanism for the evolution of rhythmic synchronization in humans. Despite the centrality of both rhythm and emotion to human and nonhuman communicatio
Rhythmicity is a composite competence that spans perceptual, motor, and socio-cognitive abilities. This is highly salient when adopting a developmental perspective, as we do in this chapter that reviews data from humans and other singing primate taxa with a close (gibbons) or remote (indri lemurs) phylogenetic relatedness to our species. The findings we review show that rhythmicity develops as an
Animals communicate with a staggering diversity of rhythmic signals, yet behind all this diversity lies a small number of ethological mechanisms. In this chapter, we provide a quick review of how animal produce rhythmic signals based on these mechanisms, which span tremulation, percussion, bodily displays, stridulation, tymbalation, aerodynamic sound production (including vocalisation), as well as
The global increase in childhood overweight and obesity presents significant public health concerns due to its long-term health implications. Emerging evidence suggests that exposure to endocrine disrupting chemicals, such as per- and polyfluoroalkylated substances (PFAS), may be obesogenic and contribute to adiposity. This study aimed to investigate the association between prenatal PFAS exposure
Nanotechnology offers promising perspectives for revolutionizing agriculture by enhancing productivity and sustainability. Although the global agricultural nanotechnology market was valued at US$ 352.4 billion in 2023 and is estimated to reach US$ 868.9 billion by 2031, concerns about adverse environmental effects persist. This review summarizes the latest developments and perspectives of nanotech
Plastic contamination has become a major environmental concern and impacts human health, and yet this is still a topic that remains largely understudied. Effects of macro- and microplastics on soil physical, chemical, and biological properties, including soil biota, are considered adverse for soils. Due to their small size and porous surface, microplastics can also be a new environmental concern b
Under various forms of international cooperation, especially EU law, Swedish authorities are obliged to recognize foreign administrative decisions. The point of departure under Swedish law is that foreign administrative decisions have no legal status as such, but need to be recognized in Swedish law. In Swedish legal discourse, it is clear that foreign decisions are regarded as matters of ‘law’ an
We analyzed the evolution of the radial profiles and the azimuthal variations of the stellar metallicities from the VINTERGATAN simulation of a Milky Way-like galaxy. We find that negative gradients exist as soon as the disk settles at high redshift, and are maintained throughout the long-term evolution of the galaxy, including during major merger events. The inside-out growth of the disk and an o
EU countries have committed to taking national measures to reduce the average energy use of residential buildings by 16% by 2030 and 20–22% by 2035. Each country has decided how to achieve this and which buildings to focus on. However, certain categories of residential buildings, including historical buildings but also second homes, may be exempt from these obligations. In Sweden, second homes con
Given the global climate crisis, the electrification of road transport has accelerated in recent decades as a strategy to mitigate global greenhouse gas emissions, with the share of Battery Electric Vehicles (BEVs) increasing exponentially. While BEVs provide substantial environmental advantages during their operational phase compared to combustion-powered vehicles, they require an extensive charg
Live-cell super-resolution microscopy enables the imaging of biological structure dynamics below the diffraction limit. Here we present enhanced super-resolution radial fluctuations (eSRRF), substantially improving image fidelity and resolution compared to the original SRRF method. eSRRF incorporates automated parameter optimization based on the data itself, giving insight into the trade-off betwe
Optical microscopy is an indispensable tool in life sciences research, but conventional techniques require compromises between imaging parameters like speed, resolution, field of view and phototoxicity. To overcome these limitations, data-driven microscopes incorporate feedback loops between data acquisition and analysis. This review overviews how machine learning enables automated image analysis
The node of Ranvier is the key element in saltatory conduction along myelinated axons, but its specific protein organization remains elusive in the human species. To shed light on nanoscale anatomy of the human node of Ranvier in health and disease, we assessed human nerve biopsies of patients with polyneuropathy by super-resolution fluorescence microscopy. We applied direct stochastic optical rec
Regionalekonomiska skillnader och varierad befolkningsutvecklinghar under lång tid präglat Sveriges samhällsdynamik. Genom enhistoriskanalys från 1860-talet och framåt visar denna rapport hurregional ojämlikhet i Sverige tidvis har ökat och tidvis har minskat.Den ekonomiska tillväxten har sedan 1980 främst gynnat större regioneri ekonomisk- och befolkningsbemärkelse, medan mindre områdenhalkat eft
Resulting from a combination of genetic and environmental factors, type 2 diabetes is highly heterogeneous in manifestation and disease progression, with the only common feature being chronic hyperglycaemia. In spite of vigorous efforts to elucidate the pathogenetic origins and natural course of the disease, there is still a lack of biomarkers and tools for prevention, disease stratification and t
