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Leukocyte recruitment is a rate-limiting step in inflammatory disease. Tissue accumulation of leukocytes is a multi-step process comprising leukocyte rolling, adhesion and transmigration across the vascular endothelium. The aim of this thesis was to investigate the mechanisms underlying ischemia-reperfusion (I/R)-induced leukocyte-endothelial cell interactions in the colon. For this purpose, intra
