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New alternatives for treatment of overactive bladder (OAB) syndrome are continuously being explored. Despite ongoing nonclinical and clinical research, few new principles have evolved. We can expect future new additions to existing drug classes and different combinations of existing options. New antimuscarinics are in development, but we do not know if they offer any advantages to currently availa
The orbital area contains a variety of anatomical structures including the eyelids, tarsal conjunctiva, caruncle, lacrimal gland, lacrimal drainage system, skin, skin adnexa, and soft tissues. It is surrounded by bone and cartilaginous structures and is highly vascularized and interspersed by the cranial nerves. This complex of neighboring, highly specialized tissues results in a large spectrum of
Due to the complex anatomy of the mediastinum and its proximity to a number of organs, a variety of neoplastic and nonneoplastic lesions may occur in the mediastinum. The majority of these are accessible via fine-needle aspiration cytology (FNAC). The main indication for FNA in the mediastinum is to distinguish between neoplasm and nonneoplastic conditions and between benign and malignant neoplasm
As we become increasingly conscious of the entangled nature of human existence, we need to become more attuned to the needs of other species, and things on this planet we are bound to. This presents us with an opportunity to rethink in whose interest we approach architectural design, and to bring vital voices into the process that have – until now – been unable to make themselves heard. We conduct
Inappropriate bricklaying techniques can result in extruded mortar joints, which may partially fill the air gaps within brick veneer timber frame walls. This leads to an unintended connection or “bridge” between the brick masonry cladding and its adjacent layer (such as insulation or weather-resistant barriers). This bridging effect compromises the capillary break function of the air gap, allowing
Cytological examination of specimens obtained from bronchial tree and lung tissue is a cost-effective, safe, and fast method of diagnosing lung disease. There are many established sampling and preparation techniques, producing cytological specimens for routine microscopic examinations, and a spectrum of ancillary methods such as microbiology, cytochemical, immunocytochemical, and molecular genetic
This book is not only a compilation of the knowledge and experiences of the best robotic surgeons around the world, but it has also incorporated the recent advances and updates in Gynaecological surgery. It is designed to provide a detailed guide to common robotic Gynaecologic procedures for the purpose of helping novice surgeons in their transition to robotic surgery and seasoned robotic surgeons
Comprehensive Sexuality Education (CSE) is central to promoting adolescents’ sexual health and rights. In Sweden, CSE is now referred to as Sexuality, Consent and Relationships (SCR) education, following a curriculum revision in 2022. This study explored how upper secondary school students (aged 16–19) experienced SCR education. A digital questionnaire was completed in the classroom by 1378 studen
In this editorial, we discuss the added value of the novel TCRBC1 antibody for immunohistochemistry in the differential diagnostics in haematopathology and promote its implementation in current diagnostic algorithms.
Morphologic diagnosis of inflammatory skin lesions is traditionally performed with punch biopsies or incisional biopsies. Skin nodules are excised for both curative and diagnostic purposes. Fine-needle aspiration cytology (FNAC) of skin nodules offers the possibility of avoiding surgical biopsy and provides rapid diagnosis, making it a valuable examination tool in cases of metastatic depositions i
Fine-needle aspiration cytology (FNAC) has been widely used as a tool to obtain specimens for the morphological diagnosis of numerous lesions in a variety of locations for more than 80 years. In many clinical situations, FNAC can render a definitive diagnosis either from aspiration smears alone using well-defined cytological criteria or from smears combined with clinical data, radiological finding
The main indication for cytologic study of the liver is the evaluation of mass-forming lesions, either symptomatic or incidentally discovered. Recent major progress in imaging methods is shifting the spectrum of cytologic diagnostics toward smaller lesions, which are often challenging. The convenience of relatively easy fine-needle aspiration (FNA) procedures with high diagnostic accuracy and low
