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Correlation between acetabular index at 3 and 12 months of age : a longitudinal radiographic study of 228 neonates treated for 6 or 12 weeks with the von Rosen splint for developmental dysplasia of the hip

BACKGROUND AND PURPOSE: Developmental dysplasia of the hip (DDH) affects around 1.5% of newborns in Sweden with few late detected cases (0.12 per 10,000). The most common treatment for DDH in Sweden is with the von Rosen splint, with radiographs at 3 and 12 months of age. Little is known about the remodeling of acetabular dysplasia following treatment initiated in the neonatal period. We aimed to

Incidence, treatment, and survival of patients with isolated colorectal lung metastases : A registry-based retrospective cohort study

Background: The benefit of surgical resection for colorectal cancer (CRC) lung metastases is unclear. The aim was to investigate the incidence, treatment strategy, and 5-year overall survival (OS) in CRC patients with isolated lung metastases. Methods: This registry-based retrospective cohort study included patients treated with curative resection of CRC within the county of Skåne during the perio

Pseudomonas aeruginosa elastase down-regulates host inflammatory responses by degrading cytokines and chemokines : a non-healing wound perspective

Non-healing venous leg ulcers are characterized by dysfunctional wound healing and frequently exhibit an absence of classical inflammatory signs, despite substantial bacterial loads of the Gram-negative pathogen Pseudomonas aeruginosa. To investigate this clinical observation, we used a porcine wound infection model and complementary in vitro cell and enzymatic activity assays. In vivo, P. aerugin

A framework for assessing the contribution of alternative food initiatives to food system transformations towards sustainability

Alternative food initiatives are vital for transforming food systems towards sustainability by challenging, replacing, and complementing the status quo. Understanding how these initiatives contribute to transformation requires attention not only to their intended outcomes but also to the processes through which these outcomes contribute to broader social change. Existing assessment frameworks rare

Supportive housing residents’ experiences of the intervention active in my home

Background: The occupational therapy intervention, Active in My Home (AiMH), puts occupational engagement, participation in society and personal recovery in focus and includes increased staff support. Aims/Objectives: To investigate how the residents experienced the AiMH support, with a focus on their possibilities for engaging in occupations and participating in society after the intervention. Ma

High one-year mortality following intensive care among adults with influenza A(H1N1)pdm09, A(H3N2), or B in Southern Sweden : a retrospective observational study

Background: Influenza ranges from a mild and self-limiting infection to a life-threatening disease with high mortality despite intensive care. Conclusive data on the association between influenza type/subtype and mortality among adults treated at intensive care units (ICU) is lacking. Objectives: To investigate the mortality in adults admitted to ICU with laboratory-confirmed influenza during thre

Introduction

This volume is one of the main outcomes of the 5-years research project The Medieval Reception of Aristotle’s Topics: A Pragmatic Account of Dialectical Argumentation? (henceforth Topica) The aim of the project was to study the medieval reception of Aristotle’s Topics, as the title indicates, and to produce critical editions of two of the main commentaries on the Topics from the thirteenth century

The symmetry coefficient of positively homogeneous functions

The Bregman distance is a central tool in convex optimization, particularly in first-order gradient descent and proximal-based algorithms. Such methods enable optimization of functions without Lipschitz continuous gradients by leveraging the concept of relative smoothness, with respect to a reference function h. A key factor in determining the full range of allowed step sizes in Bregman schemes is

The 3D Value Framework for Sustainable Access to Effective Antibiotics

Sustainable access to effective antibiotics is a main rationale for addressing antimicrobial resistance, for calls to enhance antibiotic supply security and for development support to promote health system capacity in low- and middle-income settings. Standard models for valuing pharmaceuticals fail to capture the full value of sustainable access to effective antibiotics. In effect, assessments of