Filtyp
We assessed if fasting plasma insulin levels in pregnant women with obesity are associated with newborns’ abdominal fat deposition (dual-energy X-ray absorptiometry) and with cord blood DNA methylation (450k array) in 232 mother–child pairs from the Treatment of Obese Pregnant women (TOP) study. Fasting maternal insulin at 18-20gw was associated with abdominal/total fat mass ratio in newborns inde
Stabell and Fjeldstad (1998) proposed three value configurations; the value shop, the value chain and the value network based on Thompson’s (1967) three technologies as a typology. However, that Thompson’s technologies constitute a typology has been criticized (cf Barbini and Neri, 2017). Also, research has highlighted increased shifts in value configurations and hybrid forms. Thus, the question a
Objective: To identify signature proteins potentially linked to resistance to autoimmunity in the blood of centenarians. Methods: We conducted in silico data mining of previously published proteomic results using the Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) and PHENOPEDIA databases. Results: Sixteen autoimmune disease-related proteins were identified within the proteomi
Background: To investigate a patient-level single imputation approach for patient reported outcomes (PROs) that express similar contents or associated PROs, where a PRO whose value is missing at a particular timepoint is substituted by another PRO whose value is available at the same timepoint. Methods: We performed a simulation study on registry-based spondyloarthritis data to explore the potenti
There is scientific consensus that limiting warming in line with the Paris Agreement goals requires reaching net zero CO2 emissions by mid-century and net negative emissions thereafter. Because of the entrenchment of current fossil fuel energy and feedstock demand estimated in almost all global modelled scenarios, 'abated' fossil fuel and industrial process and product use (IPPU) CO2 emissions, us
Background: The impact of air pollution and road traffic noise on depression remains inconclusive. This study examined long-term residential exposure to air pollutants and road traffic noise in relation to dispensed antidepressant medications. Methods: A cohort study was conducted using the Swedish Malmö Diet and Cancer Study, with the outcome defined as a first dispensed antidepressant (ATC: N06A
Introduction Ischaemia-reperfusion (I/R) injury remains a major challenge in heart transplantation, with mortality risk increasing significantly when allograft ischaemic time exceeds 4 hours. Non-ischaemic heart preservation (NIHP), using continuous hypothermic perfusion, has shown promise in preliminary studies for reducing I/R injury and improving outcomes. This randomised controlled trial aims
Objectives: To quantify the influence of lifestyle factors on tumour necrosis factor inhibitor (TNFi) treatment response, in axial spondyloarthritis (axSpA). Methods: Data on biologics-naïve adults with axSpA were captured from European rheumatology registries. Information on lifestyle factors (smoking, overweight/obesity, and/or alcohol consumption) were identified ± 30 days of commencing their f
The investigation of carbon monoxide (CO) adsorption on the unreconstructed Ir(100)-(1 × 1) surface under ultra-high vacuum (UHV) conditions is studied with scanning tunneling microscopy (STM), low-energy electron diffraction (LEED), and high-resolution core-level spectroscopy (HRCLS). At a low coverage of 0.5 ML (monolayer), CO molecules adopt a previously documented c(2 × 2) structure, having CO
A novel approach combining 3D printing, phase inversion, and microwave plasma-enhanced chemical vapor deposition is presented. This technique enables the creation of carbon-based electrodes with precise micro- and nanoscale control, offering potential for sustainable and high-performance wastewater treatment applications. The synthesized 3D carbon scaffolds, enriched with B,N-doped carbon nanostru
Over the last century, district heating (DH) has only achieved global market shares of around 10 %. To reach its potential market shares of 25–50 % in Europe by 2050, growth must drastically accelerate. But deployment of DH is hindered by barriers, potentially slowing this fast-paced transition of the heat system. In this paper, we identify barriers to the deployment of DH through manual and GPT-a
The recognition of amine groups by ninhydrin, along with a simple mathematical algorithm, showed that di- and tripeptides derived from dietary protein are the major end products of protein digestion entering the blood postprandially. There are thousands of oligopeptides appearing in the gut during protein digestion. However, the presented study on a pig model clearly shows that peptides longer tha
A NNW-trending mafic dyke from the central-western Bastar craton yields a U[sbnd]Pb ID-TIMS baddeleyite age of 1944 ± 6 Ma. By correlating additional dykes with similar trend and geochemical characteristics, we identify a previously unrecognized dyke swarm, named herein the Pakhanjore swarm. Geochemical evidence suggests that the studied rocks are derived from partial melting of a spinel-rich, sha
Background: People seeking refuge and asylum must often endure diverse adversities before, during, and after migration, making them more susceptible to develop psychological problems. The effect of post-migration stressors on responsiveness to psychological treatment is unclear.Objectives: To: (1) evaluate the scope of the literature on the relation between post-migration stressors (e.g. struggles
A much debated topic in recent studies of ultrafast exciton dynamics in molecular aggregates has been the precise definition of the exciton coherence domain in the B850 aggregate of photosynthetic purple bacteria. In this work we compare several measures of exciton delocalization and their variation with temperature, inhomogeneous broadening, and time. We find that the exciton wave packet prepared
We report observations of ultrafast carotenoid band shifts correlated with energy transfer dynamics between bacteriochlorophyll (BChl) molecules within the peripheral light-harvesting complex (LH2) from the photosynthetic bacterium Rhodobacter sphaeroides. Direct excitation of the bacteriochlorophyll Q(y) bands yielded distinct changes in the carotenoid S2 absorption from 430 to 530 nm. Transient
The properties of elementary excited states in the B850 band of the peripheral light-harvesting antenna (LH2) of the photosynthetic purple bacterium Rhodobacter sphaeroides has been studied at room temperature by means of femtosecond transient absorption experiments combined with computer simulations. Polarized pump-probe kinetics have a fast component of 100 and 65 fs for the anisotropic and isot
The doorway-window representation of sequential pump-probe spectroscopy, derived by solving the nonlinear exciton equations, is used to study exciton dynamics in molecular aggregates. Exciton relaxation is incorporated through a multilevel Redfield relaxation superoperator calculated using the Brownian oscillator spectral density for the collective phonon coordinates. Optical pulses are included u
