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Taxonomic profiling is a key component of ancient metagenomic analysis, however it is also susceptible to false-positive identifications. In particular, taxonomic classification tools from the Kraken family, such as Kraken2 and KrakenUniq, are highly sensitive to the choice of filtering options. To address this issue, various filtering approaches have been proposed. In this study, I conduct a comp
Rationale: Benzodiazepines, gabapentinoids, hypnotics, and opioids can depress respiration, alter sleep, and potentially affect outcomes in individuals treated with home mechanical ventilation (HMV) for obesity hypoventilation syndrome (OHS). Objectives: To analyze the association of benzodiazepines, gabapentinoids, hypnotics, and opioid use with hospitalization-free survival and mortality after s
Lakes and streams play an important role in the global carbon cycle through carbon sedimentation and evasion. The development of carbon processes in the water quality model WSFS-Vemala (Vemala) presents a significant advancement in simulating carbon dynamics, particularly in capturing both total organic (TOC) and inorganic (TIC) carbon processes and their contributions to carbon retention and emis
Both heterojunction and core–shell photocatalysts have demonstrated promising performance in photocatalytic CO2 conversions to fuels. However, fundamental knowledge of heterojunctions in core–shell structures is highly desired to facilitate the design of future photocatalysts. By combining advanced experimental characterizations and density functional theory (DFT) calculations, the role of the Cu2
The mcstas_gisans framework is a collection of Python scripts and modules tofacilitate the simulation of grazing-incidence small-angle neutron scattering(GISANS) experiments. This approach combines McStas instrument simulationwith BornAgain sample modeling capabilities. The Monte Carlo Particle Listsformat for particle trajectory allows exchange between simulations that enablesseamless transition
Several methods of surgically treating displaced, ulno-humerally stable olecranon fractures (Mayo type 2a and 2b) have been suggested. Cerclage wires have been used for at least a century to achieve fracture fixation but have been replaced by tension band wiring or plate fixation as the commonly recognized "gold standard" treatments. Thin soft tissues and migrating K-wires result in high complicat
Ghostly ideals are among the most mysterious objects in coarse index theory. In this paper we show that if a metric space X with bounded geometry admits a coarse embedding into an ℓp-space (1≤p<∞), then the canonical inclusion from any geometric ideal to the corresponding ghostly ideal induces an isomorphism in K-theory. As consequences, we deduce that such spaces satisfy the relative coarse Baum-
Functional somatic syndromes frequently co-occur with internalizing disorders such as anxiety disorders and major depressive disorder. Both show familial associations with immune-mediated diseases. Here, we estimate genetic and environmental contributions to functional somatic syndromes and their overlap with immune-mediated diseases, with internalizing disorders included for comparison. The study
Dopaminergic medication used in disorders like Parkinson's disease (PD) and restless legs syndrome can cause impulsive-compulsive behaviour (ICB), often with strong negative effects on patients' quality of life. This narrative review presents translational evidence on iatrogenic ICB, taking findings from epidemiological, clinical, neuroimaging and preclinical studies into consideration. Epidemiolo
Online hemodiafiltration (HDF) is a dialysis modality that can improve patient outcomes beyond those achieved with conventional high-flux hemodialysis (HD) in patients with kidney failure. The CONVINCE trial, the latest and the largest of a series of randomized trials comparing HDF with HD, demonstrated a 23% reduction in the risk of all-cause mortality with high-volume HDF compared to high-flux H
Polysaccharide degradation by microorganisms is essential in driving global nutrient cycling, developing renewable fuels or chemicals, and promoting human gut health. However, complex polysaccharides are often insoluble, making it challenging to study degradation with soluble enzymes or to measure microbial growth. Several protocols exist to address this challenge, including 3D-printed biomass con
Volume status of a patient is difficult to assess clinically. Methods to measure plasma volume as well as changes in plasma volume in connection with fluid therapy are therefore valuable for research purposes and could potentially be used bedside to guide fluid therapy in individual patients. The objective of the present study was to evaluate hematocrit as a marker of changes in plasma volum
Background: Data are lacking on left ventricular ejection fraction (LVEF) trajectory following myocardial infarction (MI). Objectives: This study aimed to evaluate the impact of LVEF trajectory after percutaneous coronary intervention (PCI) for MI on long-term outcomes. Methods: Patients undergoing PCI for MI (2007-2022) with serial echocardiograms were identified in the Swedish Coronary Angiograp
Background and Aims: Herpes simplex virus (HSV) infection is common worldwide, but hepatic involvement is rare. HSV hepatitis is an uncommon yet frequently catastrophic cause of acute hepatitis and acute liver failure (ALF), accounting for < 1% of ALF cases while carrying very high mortality when diagnosis and antiviral therapy are delayed. Although classically associated with profound immunosuppr
This thesis explores possibilities and challenges for urban planners to contribute to a degrowth transformation. Degrowth calls for a reduction of production and consumption, a redistribution of wealth and a shift in societal norms and values to address the current environmental crises. According to the existing literature, urban planners may be able to help advance and implement degrowth. To expl
This thesis examines how cultural distance and institutional distance are associated with the ownership stakes acquired by US firms in cross-border acquisitions. Drawing on international business theory, two hypotheses were developed, proposing that greater cultural distance and institutional distance lead to lower post-acquisition ownership stakes. Applying a quantitative deductive research desig
A large empirical literature relates corporate ESG performance to corporate financial performance, but the bulk of the evidence is drawn from return on assets and market value measures rather than from operating margin, and most studies estimate a single coefficient pooled across industries. This thesis examines whether year-over-year changes in ESG score are associated with subsequent operating p
Introduction: Reversed phase liquid chromatography (RPLC) is a central analytical technique in pharmaceutical and biopharmaceutical science, where it is essential to reliably detect, separate, quantify, and purify drugs, of which a majority contain basic groups. Background: Basic analytes often exhibit poor peak shape, for example tailing, due to mixed-mode interactions with the stationary phase.
This thesis examines Europeana, the European Union's digital cultural heritage platform. The thesis evaluates whether and how Europeana's editorial choices produce particular constructions of European identity, and what patterns of inclusion and absence emerge from those findings. Through qualitative content analysis of a sample of ten exhibitions, the research maps the themes and framing
Romance and investment fraud are complex crimes to investigate. Previous research centers around these fraud’s offenders and victims. However, much less attention has been given to the perspectives of the fraud investigators, even though their central role in the investigation and prevention process. The investigators often encounter resistance from victims, due to them being exposed to social man
