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Five-membered heterocycles are a crucial moiety in medicinal chemistry and are widely present in drugs due to its broad biological profile. Disubstituted 1,2,4-triazoles are used in a variety of therapeutic applications such as anti-cancer drugs, although the synthesis can be challenging. Previously, synthetic routes required harsh conditions and small range of reagents, which limits the scope of

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Urea formaldehyde foam (UFF) is an amino-based thermoset plastic that is widely used for dry flower arrangement and decoration. Much research has been conducted to minimize the risks associated with formaldehyde emissions and recycling practices to properly dispose or re-utilize the cured UFF; however, limited research has been conducted to enhance the biodegradability of the resin. This study aim

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Per- and polyfluoroalkyl substances (PFAS) possess exceptional chemical stability due to their strong carbon–fluorine bonds, resulting in environmental persistence and degradation challenges. Therefore, developing efficient methods for carbon-fluorine bond cleavage is essential for future recycling and remediation strategies. This work investigates lanthanide-mediated reductive defluorination of 1

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The advance of quantum computing poses a fundamental threat to today's cryptographic systems. The American agency NIST advocates that all cryptographic systems transition to post-quantum cryptography (PQC) by 2035 and even earlier for more critical systems. Given the threat of harvest-now-decrypt-later attacks, there is a growing urgency for any system handling sensitive data to migrate to PQC

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This thesis explores the use of Reinforcement Learning (RL) to optimize residential energy usage in a system composed of photovoltaic (PV) panels, a battery, an electric vehicle (EV), household consumption, and the electricity grid. A Deep Q-Network (DQN) agent was developed to minimize the electricity bill by optimizing battery usage and EV charging using real residential data supplied by Siemens

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Youth dropouts in organized sports present a significant challenge across different athletic disciplines worldwide. This thesis aims to uncover the driving factors behind this phenomenon in a specific setting - among youth orienteers in Sweden - using large-scale data analysis and statistical learning. The dataset used in this study consists of historical competition results spanning the years 201

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Rättsfallspodd från Juridiska fakulteten.Hur ledde en berusad rysk militärs förehavanden på militärområde till att den norrbottniske fiskaren Åkerberg Fransson undslapp att straffas två gånger för samma gärning i ett skattemål? I det här avsnittet diskuteras Åkerberg Fransson fallet – ett viktigt mål som bl.a. ledde till att det svenska skattetilläggsförfarandet kom att omprövas i ljuset av europa

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Conspiracy Theories in the European Digital Sphere offers a comparative account of online conspiracism, considered in terms of platform preferences, ideological content, aesthetic choices, political context, flow of travel and the role online conspiracism plays in the formation of community and identity.The book examines the assumptions that inform current ways of framing and combatting online con

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Most bird species are diurnal but drastically change their diel cycle of activity to migrate at night. Nocturnal migration has been documented using different methods (e.g., experiments, radar and radio tracking, and acoustic monitoring), but accurately quantifying the proportion of nocturnal versus diurnal flight at the individual and species levels, and understanding how this behavior evolved ac

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The vertebrate retina is a uniquely complex and evolutionarily conserved structure, combining ciliary (rod and cone) and rhabdomeric (ganglion, amacrine and horizontal cells) photoreceptor lineages within a multilayered circuit. This arrangement contrasts with the ancestral bilaterian cephalic pattern, where rhabdomeric photoreceptors dominate lateral eyes and ciliary photoreceptors are largely li

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Abstract in FrenchCet article examine la réception dominicaine de La Croix de Jésus de Louis Chardon dans l’entre-deux-guerres, en s’appuyant sur des sources d’archives inédites, dont une réponse de François Florand à ses critiques restée jusqu’ici non publiée. Il retrace comment la redécouverte de Chardon par Bremond a engagé Garrigou-Lagrange dans une lecture défensive de la mystique thomiste, cThis article examines the Dominican reception of Louis Chardon’s La Croix de Jésus in the interwar period, drawing on unpublished archival sources, including a previously unedited response by François Florand to his critics. It traces how Bremond’s rediscovery of Chardon drew Garrigou-Lagrange into a defensive reading of Thomist mysticism, how Florand’s 1937 edition presented Chardon as a Thomism