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BACKGROUND AND PURPOSE The amino acid glutamate (Glu) is the primary excitatory neurotransmitter in human brain and is involved in both synaptic transmission as well as metabolic pathways. Dysfunction of glutamate concentration in the brain has been implicated in neurological diseases, such as epilepsy, Alzheimer’s disease, schizophrenia and essential tremor. Non-invasive detection of glutamate co
