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Filtration through porous media is the oldest form of drinking water treatment and, to this day, constitutes a focal point of research in water engineering. Mathematical models of filtration are often used in conjunction with supplementary models of concurrent phenomena. For instance, both fluid flow inside and outside the filtering medium are of interest, and models of both flow through porous me

Forests are integral to the global carbon cycle, acting as major carbon sinks, though their capacity can be altered by climate and land use changes. India has a diverse forest ecosystem, but the dynamics and changes in its carbon stocks under a changing climate are not well understood. This study investigates the regional and temporal changes in vegetation carbon biomass (VCB) within Indian forest

If asset prices have no jumps it is known that the growth optimal Kelly strategy lies on the local efficient frontier, that is has maximal instantaneous Sharpe ratio. In this paper we show that, when asset prices have jumps, this property ceases to hold. However, the discrepancy is small for jumps with magnitude less than 25%. Our results further indicate that a Kelly trader fears market crashes b

One of the major subfields of chemical ecology is the study of toxins and how they mediate interactions between organisms. Toxins produced by harmful algae (phycotoxins) impact a wide variety of organisms connected to the marine food web. Significant research efforts have thus aimed to identify the ecological and evolutionary drivers behind harmful algal blooms (HABs) to facilitate their forecasti

Background: Ambulatory oxygen therapy can be used to treat exertional hypoxaemia during daily life activities in people with fibrotic interstitial lung disease (ILD). However, evidence for its efficacy is scarce. This trial aimed to compare the effects of ambulatory oxygen with ambulatory air on physical activity in daily life over 6 months in people with fibrotic ILD and isolated exertional hypox

Low back pain is common and negatively impacts quality of life and workplace productivity. However, few studies have focused on small- and medium-sized enterprises (SMEs) where risk factors are prevalent. This cross-sectional study examined the association and structural relationships between physical and social factors in low back pain among Japanese SME workers. We analyzed survey data collected

This article examines the overlaps between the AI Act and the GDPR, analysing their overall relationship, conceptual similarities and differences, as well as specific provisions in the AI Act that explicitly overlap with the GDPR. The primary focus of this article lies on AI data governance, with a detailed analysis of the requirements set out in Article 10 AI Act. This provision establishes quali

Existing LLM-based approaches remain limited by simplistic task execution, restricted tool integration, and a lack of contextual reasoning when interacting with professional GIS software. This study investigates the efficacy of a multi-agent architecture designed to enhance geospatial task execution accuracy through collaboration, reasoning and tool-use. The architecture integrates Chain of Though

Achieving ambitious policy goals such as those enshrined in the Sustainable Development Goals requires that several conditions be met. For example, it is widely believed that sustainable development policies should be legitimate, as the concept of legitimacy is frequently associated with sustainable development. Nevertheless, the notion of legitimacy is notoriously multifaceted and contested. In l

An increasing number of children grow up in joint physical custody (JPC), prompting interest in how this arrangement affects their development. Particularly, questions about the impact of JPC on early attachment development have placed young children at the forefront of scholarly attention. Yet, no systematic synthesis of research has examined attachment development in young children living in JPC

Introduction To assess how national income level influences global variation in the diagnosis and management of heart failure with preserved ejection fraction (HFpEF). Methods A web-based survey on HFpEF diagnosis and treatment was distributed worldwide from May to July 2023 through email, scientific societies, and social networks. Respondents provided demographic information and details on diagno

Highlights: What are the main findings? Motor neuron death in TIA1Δ mice occurs prior to detectable TDP-43 phosphorylation. TDP-43 accumulates and mislocalizes in the absence of phosphorylation in TIA1Δ mice, which may represent a speculative pre-aggregation-like disease stage. What are the implications of the main findings? The TIA1Δ mouse model provides a unique tool to dissect early, phosphoryl

The stringent response is a conserved stress–adaptation program in bacteria, mediated by the alarmones (p)ppGpp that reprogram transcription, translation, and metabolism. This mini–review surveys mechanistic, physiological, and evolutionary facets of alarmone singnaling across two classes of RelA/SpoT homologue (RSH) enzymes: multidomain-containing long RSHs and small alarmone synthetases/hydrolas

Background: The use of high-flow oxygen therapy (HFOT) compared with standard low-flow oxygen therapy (LFOT) may improve outcomes in people with oxygen-dependent chronic respiratory failure (CRF). The primary aim of this multicentre trial was to evaluate HFOT in addition to LFOT, compared with regular LFOT in people with CRF due to chronic obstructive pulmonary disease (COPD) or interstitial lung

Why, despite decades of warnings and solutions, does unsustainable consumption still persist? What keeps societies locked into business as usual even when the consequences are clear? This book contends that part of the answer lies in the myths we adhere to – powerful narratives that normalise the status quo, limit imagination and delay the transition to sustainability. Gathering leading scholars f

The Haro 11 galaxy merger is the closest known Lyman continuum (LyC) leaker and a strong Lyman-α (Lyα) emitter, making it an important analogue of the high-z galaxies that reionised the early Universe. To investigate how Haro 11’s properties arise, we perform a radiation hydrodynamics simulation of the merger, and create mock observations of LyC, Lyα, and Hα, from which we compute their luminositi

Background: Standardized definitions of autoimmune disease (AD) are lacking. Therefore, we aim to propose a definition of AD for register-based research and estimate the burden of AD in Sweden as registered in the National Patient Register (NPR) from 1980 to 2023. Methods: Leveraging the NPR, we defined AD as having at least two relevant International Classification of Diseases (ICD) codes represe