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In phenotype experiments in mice, determination of dynamic insulin sensitivity often uses the insulin tolerance test. However, the interpretation of this test is complicated by the counterregulation occurring at low glucose. To overcome this problem, we determined the dynamic insulin sensitivity after inhibition of endogenous insulin secretion by diazoxide (25 mg/kg) in association with intravenou
Allelopathy, the release of extracellular compounds that inhibit the growth of other microorganisms, may be one factor contributing to the formation and/or maintenance of cyanobacterial blooms. We investigated the allelopathic effects of three cyanobacterial species (Nodularia spumigena, Aphanizomenon flos-aquae and Anabaena lemmermannii) that frequently form mass-occurrences in the Baltic Sea. We
Excited state properties of three (neutral, weak and strong) acceptor-substitute carotenoids (beta-carotene) are studied theoretically with the methods of two-dimensional (2D) and three-dimensional (3D) real-space analysis. The influences of different (neutral, weak and strong) function groups attached to the polyene chain to the excited state property of the carotenoids are discussed. By the 3D r
Propofol, an intravenous anaesthetic, has been shown to interact with the beta -subunit of the gamma -amino butyric acid(A) (GABA(A) ) receptor and also to cause changes in [Ca2+ ](i) . The GABA(A) receptor, a suggested target for anaesthetics, is known to be regulated by kinases. We have investigated if tyrosine kinase is involved in the intracellular signal system used by propofol to cause anaes
Thumbelina is one of Hans Christian Andersen´s most well-known tales, found worldwide in a wealth of translations and many illustrative versions, featuring not only in printed forms but also as children´s theatre, animated films and – in the bicentenary year of 2005 – also as a ballet with scenography and costume by Her Majesty Margrethe II, Queen of Denmark. In Odense, Andersen´s native city, the
Clinical vascular features, either as manifest vascular disease or as cardiovascular risk factors were compared in AD with and without neuropathological white matter disease (WMD). The aim of the study was to investigate whether the presence of WMD and the severity of either AD pathology or WMD were associated with different cardiovascular profiles. A total of 44 AD cases were retrospectively stud
Artikeln ger en beskrivning över den kommande generationsväxlingen inom VA och övrig kommunalteknik samt vad som behöver göras.
En behandlingsarm vad gäller hormonsubstitution i klimakteriet inom Women’s Health Initiative-studien har nyligen avbrutits, eftersom riskerna bedömdes överstiga fördelarna. De tydligaste effekterna var ökad risk för venös tromboembolisk sjukdom, minskad risk för frakturer, avsaknad av gynnsam effekt på kranskärlssjukdom samt tidsberoende riskökning för bröstcancer. Enligt nya amerikanska rekommen
Results are reported for biosensors based on two different preparations of the same enzyme, laccase from Cerrena unicolor, one lyophilized and one stored frozen at - 18degreesC, for monitoring phenolic compounds. The enzyme was adsorbed on graphite electrodes and these were used in a flow through wall jet cell connected to a flow injection set-up. The electrodes were used at - 50 mV vs. AgAgCl. Th
It is a common belief that ticks are more visible and easier to detect on light clothing in comparison with dark clothing. We studied which of the clothing, light or dark, had the least attractive effect on Ixodes ricinus, thus minimizing exposure and thereby in theory helping to prevent tick-borne diseases in humans. 10 participants, exposed by walking in tick endemic areas, wore alternately ligh
The passerine major histocompatibility complex (MHC) class I and IIB genes are different from those of the avian model species the chicken because passerines have (1) a larger number of MHC genes, (2) MHC genes with longer introns, and (3) MHC genes that are pseudo-genes. Most passerine MHC genes are transcribed (coding), extremely variable and subject to balancing selection. The high genetic dive
A diagnosis-prescribing study was performed in 5 Swedish counties during 1 week in November in 2000 and repeated in 2002. The aim of the present study was to analyse data for children 0-15 y of age who consulted a general practitioner with symptoms of an infection. During the 2 weeks studied, 4049 children were consulted. Respiratory tract infections (RTI) were the predominant diagnoses, above all
Catalyst from a Perstorp Formox formaldehyde plant, operating with high inlet concentration of methanol (10.2 vol.%), was discharged from single tubes of a multi-tube reactor after half the expected lifetime of the catalyst and again after termination of the load. Each tube was filled with two different layers of catalyst. From the inlet of the reactor the first layer was a catalyst mixed with ine
Background: Many genome-wide scans aimed at complex traits have been statistically underpowered due to small sample size. Combining data from several genome-wide screens with comparable quantitative phenotype data should improve statistical power for the localisation of genomic regions contributing to these traits. Objective: To perform a genome-wide screen for loci affecting adult stature by comb
