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Although Parkinson's disease is a movement disorder, in many patients cognitive dysfunction is an important clinical sign. It is not yet clear whether this is attributable solely to a decrease in dopamine levels, or whether other neurotransmitter systems might be involved as well. In the present study, the importance of the mesocorticolimbic dopamine pathway and a possible convergence with forebra

Popular Abstract in Swedish Polymermembranbränsleceller (PEM) anses vara en mycket lovande teknik inom fordonsindustrin på grund av dess kompakthet i storlek, höga verkningsgrader samt låga arbetstryck och temperaturer. De senaste åren har tekniken varit fokus för en anseenlig mängd forskning. PEM-bränsleceller har den stora fördelen att energiomvandlingseffektiviteten har potential för att vara bThis thesis presents numerical simulations of reacting transport phenomena in polymer electrolyte membrane (PEM) fuel cells. Broadly, the presented work is subdivided into macro and microscale simulations. In macroscale simulations, a unit PEM fuel cell with interdigitated flow field configurations is simulated keeping in mind all the essential transport mechanisms, i.e., transport of species, ion

Aims Baseline adiponectin concentrations predict incident Type 2 diabetes mellitus in the Diabetes Prevention Program. We tested the hypothesis that common variants in the genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1, ADIPOR2) would associate with circulating adiponectin concentrations and/or with diabetes incidence in the Diabetes Prevention Program population. Methods Seventy-s

This doctoral thesis is comprised of five parts in the field of biomedical signal processing with focus on methods for use in hemodialysis as well as in cardiac applications. The problem of predicting hypotension is the main concern in the parts were data from patients undergoing hemodialysis are used. In Part I, a newly developed method for heart rate variability (HRV) analysis in the presence of

Phonetic markedness regarding linguistically relevant tonal patterns (Accent 2, boundary tones) in Central Swedish is discussed. Both tonal markedness and F0 turning points are assumed to be important cues for anticipatory attention to grammatical structure during speech processing. Empirical evidence from neuro- linguistic and psycholinguistic experiments for the assumed relation between anticipa

Industrialized production of building components, or entire houses, reduces activities at the construction site to the assembly of parts and has the potential to increase productivity and reduce the design effort invested in every project. However, in order to realize all of the potential efficiency gains that use of predefined components could deliver effective, interoperable information manageme

Welinders Swedish history of archaeology: A review of Stig Welinder’s book “Min svenska arkeologihistoria” (My Swedish history of archaeology) (2003).

OBJECTIVE. Severe (PiZZ) alpha(1)-antitrypsin (AAT) deficiency is a risk factor for liver disease, i.e. juvenile cirrhosis in infancy, and cirrhosis and hepatoma in adulthood. Little is known about the risk of liver disease in individuals with moderate (PiSZ) AAT deficiency. To investigate the natural course of AAT deficiency, a cohort of PiZZ and PiSZ individuals identified by the Swedish Nationa

There is a functional relationship between the heparan sulfate proteoglycan glypican-1 and the amyloid precursor protein of Alzheimer disease. In wild-type mouse embryonic fibroblasts, expression and processing of the amyloid precursor protein is required for endosome-to-nucleus translocation of anhydromannose-containing heparan sulfate released from S-nitrosylated glypican-1 by ascorbate-induced,

In 1867 Alexander Melville Bell conceived the high-low front-back tongue position model for vowels, including the concept of central vowels. This model was rapidly accepted by the phonetics community, but it has never been validated. This article reports an examination of 38 sets of X-ray tracings of vowels from 15 different languages, published in the past half century. This corroborates the char

Objective. To investigate the inter- and intra-observer reliability of both qualitative and quantitative parameters used in the assessment of nail-fold capillaroscopy images.Methods. Fifty mosaic nail-fold images of healthy controls (n = 10), patients with primary RP (n = 10) and SSc (n = 30) were assessed in random order by two blinded observers on two occasions at centres in Sweden, UK and The N

Popular Abstract in Swedish Fjärrvärme är ett centraliserat uppvärmningssystem där varmt vatten distribueras i ett rörnätverk och används främst till byggnadsuppvärmning och för att värma varmvatten. Fjärrvärme finns i alla länder på norra halvklotet men har störst marknadsandel i Norden och Baltikum. I Sverige används fjärrvärme för att värma c:a 60% av all byggnadsyta. Två stora fördelar med fjäRenewable energy sources dominated the world energy supply until the beginning of the 20th century, when fossil energy became the dominant energy source worldwide. Today, fossil fuels contribute to over 80% of world energy supply. But there are two major reasons why fossil energy use has to stop. First, fossil energy is limited and will not last forever. Second, emissions of carbon dioxide change