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PURPOSE: The urodynamic effects of intrathecal neurokinin (NK) receptor blockade on L-dopa-induced bladder hyperactivity were investigated in a rat model. MATERIALS AND METHODS: Continuous cystometry was performed in normal, conscious, female Sprague-Dawley rats. RESULTS: In rats pretreated with intraperitoneal carbidopa 50 mg./kg., intraperitoneal L-dopa 50 mg./kg. caused bladder hyperactivity th

Determination of heart status during dialysis can im- prove patient monitoring. Pressure sensors in the dialysis machine measures the heart pulses that propagates in the body and enter the extracorporeal blood circuit. A peri- staltic blood pump, located in the same circuit, introduces strong periodic pressure pulses that interfere with the much weaker cardiac component. These signal characteristi

There is limited knowledge of knee laxity in the long term after a complete anterior cruciate ligament (ACL) tear treated without ACL reconstruction. The aim of this study was (1) to describe the clinical course of knee laxity after a complete ACL tear over 15 years, and (2) to study the association between knee laxity and meniscal injuries and the development of knee osteoarthritis (OA). We studi

Granath A, Norrby-Teglund A, Uddman R, Cardell L-O. Reduced iNOS expression in adenoids from children with otitis media with effusion. Pediatr Allergy Immunol 2010: 21: 1151-1156. © 2010 John Wiley & Sons A/S Nitric oxide (NO) is a key mediator in the local immune response of human airways. Inducible NO-synthases (iNOS), and endothelial NO-synthases (eNOS) are two enzymes known to regulate its

This paper elaborates theoretical and methodological aspects of design processes in a disability context and aims to relate them to other sciences. It particularly emphasizes situated aspects of research: the need for being there, with the users in their

Employing new measures (Implicit Association Test) to study the classic issue of moral orientations, we predicted and found gender differences in implicit associations to the concepts of justice and care. Specifically, we found that men more strongly associate justice vs. care with importance and with themselves than women. However, participants’ explicit ratings did not reveal any clear patterns

It has been known for a long time that GABAergic Purkinje cells in the cerebellar cortex, as well as their target neurons in the cerebellar nuclei, are spontaneously active. The cerebellar output will, therefore, depend on how input is integrated into this spontaneous activity. It has been shown that input from climbing fibers originating in the inferior olive controls the spontaneous activity in

This study examined how women and men cope with stress during a period of organisational change and how the coping strategies are related to health. Questionnaire responses were obtained from 98 female and male administrators of health care service working in a Swedish governmental County Council during a period of downsizing. In line with earlier studies the results showed women to be more likely