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Association of int2/hst1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis

The human proto-oncogene INT2 (homologous to the mouse INT2 gene, implicated in proviral induced mammary carcinoma) has been mapped to chromosome llql3 and found to share band localisation with, among others, the HST1 proto-oncogene. Both genes are members of the fibroblast growth factor family. In the present study, coamplification (2-15 copies) of the INT2/HST1 genes was found in 27 (9%) of 311

Sgea20 1 schema ht2018

SGEA20-1_SGEL40_HT_2018_Schema_2018-06-12 – 1 – SGEA20:1 ÄMNESINTRODUKTION SGEL40 PLANERINGENS FÖRUTSÄTTNINGAR 1 Höstterminen 2018 SCHEMA Dag Tid Moment Lokal Undervisar Mån. 3/9 09:15-10:00 Kursintroduktion* Världen Flera 10:15-12:00 Föreläsning 1: Karten som verktyg Världen OH Tis. 4/9 10:15-12:00 Föreläsning 2: Geografins rötter och idévärld A Världen HGL 13:15-15:00 Lab 1 (grupp 1)* Smil OH 13

https://www.keg.lu.se/sites/keg.lu.se/files/sgea20_1_schema_ht2018.pdf - 2026-05-30

Sgel64 schema vt18 vers180104

SGEL64 - Samhällsgeografi: GIS i urban och regional planering: en introduktion, 7,5 hp 2018-03-20 till 2018-04-24 Datum Dag Tid Typ Moment Grupp Lärare Sal 2018-03-20 Tis 11-13 F Kursintroduktion & Vad och Varför GIS? Alla LS 430 EM Förberedelse lab Alla 17:00 Anmälan till grupp 1 eller 2 Alla L@L 2018-03-21 Ons 9-12 Ö Modul: Introducing ArcGIS & ArcGIS Basics 1 LS 212 13-16 Ö Modul: Introducing A

https://www.keg.lu.se/sites/keg.lu.se/files/sgel64_schema_vt18_vers180104.pdf - 2026-05-30

Digital quantification of stroma percentage enhances prognostic stratification in pancreatic cancer

Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by a prominent desmoplastic stroma, which plays a crucial role in tumor biology and treatment resistance. While the stromal compartment is a defining histopathological feature of PDAC, its prognostic significance remains incompletely understood. This study aimed to quantify the stromal content in PDAC using digital pathology and

The Swedish CArdioPulmonary bioImage Study re-examination : Rationale, design, methods, and management of incidental findings

Objectives: To describe the rationale, design and data collection procedures of the Swedish CArdioPulmonary bioImage Study (SCAPIS) re-examination, which, in its further scope, aims to quantify and explain the development of atherosclerosis, pathological cardiovascular ageing, longitudinal decline in lung function and the malignant transformation of pulmonary nodules among middle-aged Swedes in th

Respiratory symptoms among epoxy-exposed workers in the wind turbine industry : a cross-sectional study

Objectives The aim was to estimate the prevalence and risk of respiratory symptoms among workers exposed to epoxy resin systems in the wind turbine industry. Methods We conducted a cross-sectional study including 180 epoxy-exposed production workers from two Danish wind turbine blade factories and 41 non-exposed office workers. Respiratory symptoms were defined as having two or more symptoms (i.e.

Schema sgea20-1 och sgel40

SGEA20-1_SGEL40_HT_2019_preliminär_schema – 1 – SGEA20:1 ÄMNESINTRODUKTION SGEL40 PLANERINGENS FÖRUTSÄTTNINGAR 1 Höstterminen 2019 PRELIMINÄRT SCHEMA = Preliminärt Dag Tid Moment Lokal Undervisar Mån. 2/9 09:15-10:00 Kursintroduktion* Världen Flera 10:15-12:00 Föreläsning 1: Kartan som verktyg Världen OH 13:15-15:00 Lab 1 (grupp 1)* Smil OH 13:15-15:00 Litteratursök, referenssystem mm (grupp 4)* G

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/schema_sgea20-1_och_sgel40.pdf - 2026-05-30

Sgea20-1 sgel40 ht 2019 schema 2019-08-15

SGEA20-1_SGEL40_HT_2019_Schema_2019-08-15 – 1 – SGEA20:1 ÄMNESINTRODUKTION SGEL40 PLANERINGENS FÖRUTSÄTTNINGAR 1 Höstterminen 2019 SCHEMA Dag Tid Moment Lokal Undervisar Mån. 2/9 09:15-10:00 Kursintroduktion* Världen Flera 10:15-12:00 Föreläsning 1: Kartan som verktyg Världen OH 13:15-15:00 Lab 1 (grupp 1)* Smil OH 13:15-15:00 Litteratursök, referenssystem mm (grupp 4)* G101 EF Tis. 3/9 08:15-10:0

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/sgea20-1_sgel40_ht_2019_schema_2019-08-15.pdf - 2026-05-30

Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes : Results from a randomized clinical trial

Aims Metformin therapy is associated with diffuse intestinal 18F-fluoro-deoxyglucose (FDG) accumulation in clinical diagnostics using routine FDG-PET imaging. We aimed to study whether metformin induced glucose uptake in intestine is associated with the improved glycaemic control in patients with type 2 diabetes. Therefore, we compared the effects of metformin and rosiglitazone on intestinal gluco

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis

Vitamin D insufficiency is common, correctable, and influenced by genetic factors, and it has been associated with risk of several diseases. We sought to identify low-frequency genetic variants that strongly increase the risk of vitamin D insufficiency and tested their effect on risk of multiple sclerosis, a disease influenced by low vitamin D concentrations. We used whole-genome sequencing data f

Past and current cause-specific mortality in Eisenmenger syndrome

Aims: Eisenmenger syndrome (ES) is associated with considerable morbidity and mortality. Therapeutic strategies have changed during the 2000s in conjunction with an emphasis on specialist follow-up. The aim of this study was to determine the cause-specific mortality in ES and evaluate any relevant changes between 1977 and 2015. Methods and results: This is a retrospective, descriptive multicentre

Identifying the heterogeneity of COPD by V/P SPECT : A new tool for improving the diagnosis of parenchymal defects and grading the severity of small airways disease

Introduction: Airway obstruction and possible concomitant pulmonary diseases in COPD cannot be identified conventionally with any single diagnostic tool. We aimed to diagnose and grade COPD severity and identify pulmonary comorbidities associated with COPD with ventilation/perfusion single-photon emission computed tomography (V/P SPECT) using Technegas as the functional ventilation imaging agent.

Long-Term Outcomes After Distal Scaphoid Fractures : A 10-Year Follow-Up

Purpose: The aim of this study was to evaluate the functional, clinical, and radiological outcome 10 years after distal scaphoid fractures. Methods: From a prospective epidemiological study on posttraumatic radial-sided wrist pain, we evaluated 41 cases of distal scaphoid fractures. All cases had been treated nonsurgically in a thumb spica cast. Patients were examined using radiographs, magnetic r

Extrarenal plasma clearance of iohexol, chromium-51-ethylenediaminetetraacetic acid, and inulin in anephric pigs

RATIONALE AND OBJECTIVES: To improve the measurement of the glomerular filtration rate (GFR), we determined the extrarenal plasma clearance of the GFR markers iohexol, chromium-51-ethylenediaminetetraacetic acid (51Cr-EDTA), and inulin using 11 anephric pigs. METHODS: After an intravenous (i.v.) bolus injection of the markers, the decay curves of their plasma concentrations were monitored for 29 h

Footwear for cold work: a field study about work on high masts

A series of field studies at cold workplaces were initiated. This paper deals with the study at a telecommunication company and the main attention is paid to the thermal responses of the feet and footwear performance. The study was carried out in February. Eight male workers were the subjects. They were selected among volunteers who carried out various jobs on high masts on four different days. Th

Tumor-Associated CD68+, CD163+, and MARCO+ Macrophages as Prognostic Biomarkers in Patients With Treatment-Naïve Gastroesophageal Adenocarcinoma

Background: Despite improvements in surgical methodologies and perioperative chemo- and radiotherapy, the prognosis for patients with esophageal and gastric cancer remains poor. Hence, there is a great need to identify complementary biomarkers for improved treatment stratification. Tumor-infiltrating immune cells have been shown to impact on outcome in many types of cancer, including gastroesophag

Metabolite profiling paradoxically reveals favorable levels of lipids, markers of oxidative stress and unsaturated fatty acids in a diabetes susceptible group of Middle Eastern immigrants

Aims: The population of immigrants from the Middle East in Sweden show a higher prevalence of type 2 diabetes (T2D) compared to native Swedes. The exact reason for this is unknown. Here, we have performed metabolite profiling to investigate these differences. Methods: Metabolite profiling was conducted in Iraqi immigrants (n = 93) and native Swedes (n = 77) using two complementary mass spectrometr

Occupational exposure to whole-body vibrations and pregnancy complications : A nationwide cohort study in Sweden

Objectives Pregnancy complications are common contributors to perinatal mortality and morbidity. Still, the cause(s) of gestational hypertensive disorders and diabetes are largely unknown. Some occupational exposures have been inconsistently associated with pregnancy complications, but exposure to whole-body vibrations (WBV) has been largely overlooked even though it has been associated with adver

Epidemiology, bacteriology, and clinical characteristics of HACEK bacteremia and endocarditis : a population-based retrospective study

The objective was to describe the epidemiology, bacteriology, clinical presentation, risk factors for endocarditis (IE), diagnostic workup, and outcome of patients with bacteremia caused by the non-influenzae Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella, and Kingella genera (HACEK). A retrospective population-based cohort of patients with bacteremia collected from 2012 to 2017 was iden