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Osteoarthritis (OA) remains the most challenging arthritic disorder, with a high burden of disease and no available disease-modifying treatments. Symptomatic early-stage OA of the knee (the focus of this Review) urgently needs to be identified and defined, as efficient early-stage case finding and diagnosis in primary care would enable health-care providers to proactively and substantially reduce
We approach critically the assertion that a referendum ultimately defends the “traditional family,” by examining the articulation of anti-gender politics in Romanian parliamentary debates. We contribute theoretically by employing the concept of retrogressive mobilization in plebiscitary circumstances. We show that in Romania the contours of retrogressive mobilization transgress both the ideologica
Human rely profoundly on tactile feedback from fingertips to interact with the environment, whereas most hand prostheses used in clinics provide no tactile feedback. In this study we demonstrate the feasibility to use a tactile display glove that can be worn by a unilateral hand amputee on the remaining healthy hand to display tactile feedback from a hand prosthesis. The main benefit is that users
In an ampoule for a medicament the space accommodating the medicament is defined by an ampoule wall (1) a pierceable seal (5) closing one end of the ampoule and a piston (7) closing the other end of the ampoule. A metal containing fixation element (8) is secured to one of the parts defining the medicament accommodating space. A mixing element (9, 10) also containing a metal and having a density la
#95. The Old Folks at Home, for solo voice (2016)TITLE: The Old Folks at HomeCAT# (YEAR COMPOSED): 95 (2016) INSTRUMENTATION: solo voicePAGES: 15DURATION (APPROX): 5’00PUBLICATION: BABELSCORES®
In this paper, beam diagnostic and monitoring tools developed by the MAX IV Operations Group are discussed. In particular, beam position monitoring and accelerator tunes visualization software tools, as well as tools that directly influence the beam quality and stability, are introduced. An availability and downtime monitoring application is also presented.
Graph neural networks for crystal structures typically use the atomic positions and the atomic species as input. Unfortunately, this information is not available when predicting new materials, for which the precise geometrical information is unknown. We circumvent this problem by replacing the precise bond distances with embeddings of graph distances. This allows our networks to be applied directl
Tunnel fire risk analysis are a useful tool to ensure adequate safety levels in tunnels. This report presents the work conducted to integrate a multi-zone modelling approach into a fire risk assessment tool, called ARTU. This work was performed to improve its fire modelling predictive capabilities compared to the currently adopted 1D fire modelling representation. This is deemed to allow for the u
The breaching of planetary boundaries and excessive extraction of natural resources requires a revisited approach to consumption and production. The concept of sufficiency, which advocates meeting human needs within the planetary limits by curbing excessive consumption levels, is gaining increasing attention. Businesses are drivers of consumption, yet they have been largely overlooked as potential
This article critically examines the approach of technical experts, including engineers, natural scientists, architects, planners, and other practitioners, who are attempting to create more sustainable forms of economic development, environmental protection, and social equity. The authors identify four principal characteristics of expertise–ontological assumptions, epistemological approaches, powe
Chronic breathlessness occurs across many different conditions, often independently of disease severity. Yet, despite being strongly linked to adverse outcomes, the consideration of chronic breathlessness as a stand-alone therapeutic target remains limited. Here we use data-driven techniques to identify and confirm the stability of underlying features (factors) driving breathlessness across differ
Exact cover is a non-deterministic polynomial time (NP)-complete problem that is central to optimization challenges such as airline fleet planning and allocation of cloud computing resources. Solving exact cover requires the exploration of a solution space that increases exponentially with cardinality. Hence, it is time- and energy consuming to solve large instances of exact cover by serial comput
Ecocriticism tends to acknowledge anthropomorphisms as a possible tool to create empathy for nonhumans, but in doing so mostly labels said tool as too sentimental for serious environmental literature. This paper aims to establish a categorisation of anthropomorphisms in media that allows a more diverse and detailed analysis of humanised nonhumans. It seeks to overcome the prevailing idea that anth
Let f be a holomorphic self-map of the unit disc. We show that if log(1 − | f (z)|) is integrable on a sub-arc of the unit circle, I , then the set of points where the function f has finite Carathéodory angular derivative on I is a countable union of Beurling–Carleson sets of finite entropy. Conversely, given a countable union of Beurling–Carleson sets, E , we construct a holomorphic self-map of t
This work presents a statistical approach for estimating and analyzing the downward transport pattern and distribution of soil water by the use of pattern analysis of space-time correlation structures. This approach, called the Space-time Correlation Field, is mainly based on the analyses of correlation functions simultaneously in the space and time domain.The overall purpose of this work is to de
This Letter introduces a novel, to the best of our knowledge, method for assessing fruit quality using white-light biospeckle displacement analysis. The primary aim is to demonstrate that speckle displacement behavior differs between healthy and decaying regions, offering a unique means of gauging bioactivity levels, a feature that has not been explored in previous biospeckle research. By examinin
A comprehensive treatise for methods for fatigue estimation and fatigue life prediction in randomly excited structural systems using th rainflow cycle counting method
We are interested in studying sets of the form U ( α ) := { x ∈ X : ∃ M = M ( x ) ⩾ 1 such that ∀ N ⩾ M , ∃ 1 ⩽ n ⩽ N such that d ( T n x , x ) ⩽ | λ | − α N } , where ( X , T , d ) is our metric dynamical system and | λ | > 1 . Although many results exist for the one dimensional case, not as many are known for systems in higher dimensions and especially in the hyperbolic case. We consider X = T 2
District Heating is a cornerstone for the decarbonisation of the heating and cooling sector in Europe. Nonetheless, this technology is currently absent in a majority of the continent's urban areas, and hence the need for appropriate methods by which to estimate the cost, as well as underlying cost parameters, to assess the feasibility of developing district heating networks is of general interest.
