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Synovial proliferation in rheumatoid arthritis causes capsular distension, destruction of tendons and ligaments, and erosion of bone. The classic deformities in rheumatoid arthritis, like boutonnière or swan neck, are not consistent, and each patient may have his or her own pattern of deformities. The anatomic arrangement of the tendons enables motion of the proximal interphalangeal (PIP) joint is
A high resolution soft X-ray monochromator for the 550 MeV MAX storage ring is described. The instrument combines a plane elliptical premirror collecting a large (10 mrad) horizontal angle of radiation and a modified version of the well-known SX-700 plane grating monochromator (PGM). The modification consists of changing the original ellipsoidal focussing mirror to a plane elliptical mirror. There
Inom fysik försöker vi beskriva naturfenomen med matematiska modeller. Beroende på vilket system som ska beskrivas är olika modeller relevanta. På väldigt långa avstånd är gravitation den viktigaste kraften. Till exempel så beskrivs solsystemets dynamik av gravitation. På de kortaste avstånd som människan lyckats studera är det istället den elektromagnetiska, den svaga och den starka kraften som äIn this thesis we use effective field thory methods and models for low energy QCD in two different contexts. One is direct calculation of contributions to the anomalous magnetic moment of the muon, muon g-2. The other is estimates of systematic sources of uncertainty in lattice QCD simulations. The work is presented in five papers. Papers II, IV and V describe calculations for muon g-2 and papers
The European Spallation Source is Europe's next generation high-power neutron source utilising a linear accelerator and a rotating tungsten target to produce neutrons that will be used for fundamental research and industrial applications. The facility is co-hosted by the states of Denmark and Sweden, and while the main site will be placed in Lund, Sweden, the Data Management and Software Centre wi
In order to properly design an absorption tower for CO2 capture knowledge on the absorption rate of CO2 is required. Several methods can be used to determine the absorption rate, such as a wetted wall column (WWC), stirred absorption cell or a string of discs setup. The aim of this work was to determine the absorption flux of CO2 into different amine solutions using anew method. Two absorption sys
Preparedness and resilience planning for critical infrastructure networks requires evaluating the impact to the network when its components are disrupted. We extend the well-studied problem of component importance measures in single-commodity networks to multi-commodity networks by integrating a flow based multi-commodity optimization model with a multi-criteria decision analysis tool. A three-sta
Background: Carpenter ants (genus Camponotus) are considered to be omnivores. Nonetheless, the genome sequence of Blochmannia floridanus, the obligate intracellular endosymbiont of Camponotus floridanus, suggests a function in nutritional upgrading of host resources by the bacterium. Thus, thestrongly reduced genome of the endosymbiont retains genes for all subunits of a functional urease, as well
The rising prevalences of type 2 diabetes and obesity constitute major threats to human health globally. Powerful social and economic factors influence the distribution of these diseases among and within populations. These factors act on a substrate of individual predisposition derived from the composite effects of inherited DNA variation and a range of environmental exposures experienced througho
Next generation sequencing (NGS) methods have been widely used for diagnosis. As time and cost of sequencing has reduced sharply during the last decade, genome and exome-wide sequencing have increasingly been used. The genome and exome projects produce large amounts of variation data and the clinical relevance of large proportions of them are not known. Among various types of genetic variations, t
Introduction: Allergic rhinitis (AR) affects over 20% of the population of Europe and the United States. Allergen immunotherapy (AIT) is currently the only form of treatment that affects symptoms and modifies the progression of disease. Established forms of AIT include subcutaneous (SCIT) and sublingual (SLIT) immunotherapy and are widely effective, yet only 2-9% of eligible patients undergo thera
The evidence for associations between area characteristics and entrepreneurship is fairly consistent in most studies. These studies, however, have disregarded the fact that the areas might be constructs that have no effect on the individual differences in entrepreneurship and, furthermore, have conflated entrepreneurship and sole proprietorship, disregarding the impact of area constructs on differ
Prasugrel is a third-generation thienopyridine platelet P2Y12 adenosine diphosphate (ADP) receptor antagonist administered with aspirin for the treatment of patients with acute coronary syndrome (ACS) with planned percutaneous coronary intervention. Prasugrel is administered periprocedurally at an oral loading dose of 60 mg followed by daily maintenance doses (MDs) of 10 mg for most patients and 5
The Beamline for European Materials Engineering Research (BEER) will be built at the European Spallation Source (ESS). The diffractometer utilizes the high brilliance of the long-pulse neutron source and offers high instrument flexibility. It includes a novel chopper technique that extracts several short pulses out of the long pulse, leading to substantial intensity gain of up to an order of magni
Background: Persons with clinical onset of Alzheimer’s disease (AD) before 65 years of age are diagnosed with early-onset AD (EOAD). The prevalence of EOAD is low, but varies among studies from 6% to 16%. Most individuals with EOAD are still working, have an active social life, and might have children living at home. Therefore, the consequences of being diagnosed early with a disease that implies
Purpose: The Catquest-9SF questionnaire is a unidimensional, reliable, valid and short patient-reported outcome measure for quantifying benefits in visual functioning from cataract surgery. Our aim was to develop a formal Dutch translation, calculate norm scores, assess its validity and test-retest reliability and provide an easy way for use in clinical practice. Methods: Translation of the questi
BACKGROUND: Integrated health promotion improves clinical outcomes after hospital treatment. The first step towards implementing evidence-based health promotion in hospitals is to estimate the need for health promoting activities directed at hospital patients. The aim of this study was to identify the distribution and association of individual health risk factors in a Norwegian hospital population
