Filtyp
Physical exercise can play an important role both in primary and secondary cardiovascular disease prevention by virtue of its multisystem effects. These beneficial adaptations at the whole-body level include improvements in mitochondrial health, vascular function, and autonomic balance, together with attenuation of inflammation and the release of ‘exerkines’ with pleiotropic effects. Thus, several
The ESS linac is under construction by the ESS partner institutes (socalled In-Kind Contributors - IKC) and will operate the most powerful proton beam ever for neutron spallation source. The linac delivers 5 MW via 2 GeV protons at a repetition rate of 14 Hz at the He-cooled solid tungsten target. The pulsed neutrons, result of the spallation, will reach the science instruments after having been m
Biocatalysis has emerged as a cornerstone of sustainable manufacturing, yet conventional modes are hindered by inherent limitations such as metabolic interference, mass transfer barriers, and instability. This study presented a novel platform using fragmented Gluconobacter oxydans, combining the autonomous cofactor regeneration of whole cells with the superior substrate accessibility of free enzym
Bark beetle species of the genera Ips and Dendroctonus represent a threat to forests in both North America and Europe. Under normal circumstances, these beetles recycle dying trees into nutrients, but under certain conditions, growing populations can overcome healthy tree defenses and cause severe economic loss in forestry. The most economically relevant bark beetle species communicate with aggreg
The high neutron flux of the European Spallation Source in Lund, Sweden, opens new possibilities for neutron protein crystallography. Making full use of these gains requires dedicated instrumentation and support facilities to maximize its contribution to our understanding of biological processes at the molecular level.
The chapter argues that employees play a central yet historically overlooked role in organizational crisis communication. Traditional crisis communication has emphasized external stakeholders and managerial control, but this chapter highlights internal communication as a continuous, relational, and sensemaking process that shapes organizational legitimacy. Employees are portrayed as active sensema
Interactive AI systems - large language models, conversational agents, and chatbots - are rapidly becoming primary interfaces through which citizens access and evaluate political information. Developed and governed largely by private corporations, these systems do not merely distribute content: they shape opinion formation through sustained, adaptive, and personalised dialogue, relocating politica
In this paper we review the physics opportunities at linear e+e− colliders with a special focus on high centre-of-mass energies and beam polarisation, take a fresh look at the various accelerator technologies available or under development and, for the first time, discuss how a facility first equipped with a technology that is mature today could be upgraded with technologies of tomorrow to reach m
This paper aims to contribute to the discussion of the nature of the self-help housing market by analysing its extent and mode of operation in four self-help settlements in the intermediate sized city of Perdra, Colombia. The evidence from the survey settlements suggests that the market for self-help houses is small. Self-help settlements are dominated by a land market rather than by a housing mar
The South African forestry supply chain is a complex system that involves both the production of trees (site preparation, re-establishment, tending, and maintenance operations) and the production and distribution of wood products from plantation stands to the pulp- and sawmills. This paper reports on a study that investigated the suitability of discrete-event simulation for modelling forestry supp
PurposeIn the age of digital businesses, the rise of innovative digital transformation has made supply chain transparency (SCT) an essential research topic. While digital technologies provide possibilities for enhancing transparency in supply chains, there is limited research on how digital businesses overcome different SCT issues or provide real-time visibility and traceability. This study aims t
In May 2024 with a subsequent update in June 2025, the Swedish Medical Products Agency’s expert group revised guidelines on the management and treatment of respiratory syncytial virus (RSV) infection. This is an abridged version and commentary on the full recommendation including specific recommendations for the RSV-season 2025/2026. Key points are: (i) RSV is a seasonal, highly contagious infecti
Nomenclature for the disease widely known as Sjögren syndrome has proven unsatisfactory. Patients have perceived ‘syndrome’ as indicative of a vague collection of symptoms, prompting the Sjögren’s Foundation to abandon the term. Furthermore, the traditional distinction between ‘primary’ and ‘secondary’ forms fails to account for the complex interplay between overlapping autoimmune diseases. Follow
The HIBEAM-NNBAR program is a proposed two-stage experiment at the European Spallation Source focusing on searches for baryon number violation processes as well as ultralight dark matter. This paper presents recent advancements in computing and simulation, including machine learning for event selection, fast parametric simulations for detector studies, and detailed modeling of the time projection
Sustainable access to effective antibiotics is a main rationale for addressing antimicrobial resistance, for calls to enhance antibiotic supply security and for development support to promote health system capacity in low- and middle-income settings. Standard models for valuing pharmaceuticals fail to capture the full value of sustainable access to effective antibiotics. In effect, assessments of
The goal of the paper is to present a distributed scheme to resolving a single path routing problem in multidomain networks. The global problem is formulated as a mixed-integer program (MIP) and approached by means of branch-and-price (B&P). Problems associated with a B&P tree nodes are decomposed using the Dantzig-Wolfe method to a set of domain subproblems coordinated by a single master
