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The maximum drawdown of a stochastic process is the largest peak-to-troughdecline observed over a given horizon [0, T]. Using arguments from extremevalue theory, we derive the limiting distribution of the maximum drawdown fora Brownian motion with positive drift as T → ∞. We show that, after suitablecentering and scaling, the maximum drawdown converges in distribution to theGumbel law.
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OBJECTIVES: The Sepsis-3 definition states the clinical criteria for sepsis but lacks clear definitions of the underlying infection. To address the lack of applicable definitions of infection for sepsis research, we propose new criteria, termed the Linder-Mellhammar criteria of infection (LMCI). The aim of this study was to validate these new infection criteria.DESIGN: A multicenter cohort study o
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The Cherenkov Telescope Array (CTA) will be the next-generation observatory in the field of very-high-energy (20 GeV to 300 TeV) gamma-ray astroparticle physics. The traditional approach to data analysis in this field is to apply quality cuts, optimized using Monte Carlo simulations, on the data acquired to maximize sensitivity. Subsequent steps of the analysis typically use the surviving events t
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The Cherenkov Telescope Array Observatory (CTAO) is the next-generation ground-based gamma-ray observatory currently under construction. It will improve over the current generation of imaging atmospheric Cherenkov telescopes (IACTs) by a factor of five to ten in sensitivity and it will be able to observe the whole sky from a combination of two sites: a northern site in La Palma, Spain, and a south
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We measured πΣ invariant mass spectra below and above the K̄N mass threshold in the K-d → NπΣ reaction in order to study the K̄N interaction and the Λ(1405) resonance. This reaction can be described by the two-step process: (i) K-N1 → K̄N followed by (ii) K̄N2 → πΣ, where N1 and N2 are nucleons bound in the deuteron. We deduced the S -wave scattering amplitude of K̄N → K̄N as well as K̄N → πΣ in I
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The unification of quantum mechanics and general relativity has long been elusive. Only recently have empirical predictions of various possible theories of quantum gravity been put to test, where a clear signal of quantum properties of gravity is still missing. The dawn of multi-messenger high-energy astrophysics has been tremendously beneficial, as it allows us to study particles with much higher
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The dissertation Deductionis coloniarum rationes & causae, submitted at Uppsala University in 1668 under the presidency of Johannes Schefferus, appears to be the firstcontribution to the Swedish discourse on the subject of colonisation and colonialism. In this paper, a translation of the text is presented with a commentary and a list of sources. In an introduction to the translation, which dis
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A central challenge in linguistics pertains to understanding how the polished, static form of a written text emerges from the messy, moment-by-moment decisions of the writer. While the structures of finished texts have been extensively theorized, and the real-time cognitive processes of writing have been widely studied, the relationship between these real-time processes and the functional linguist
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This article analyzes the effects of self-balancing in multiactive bridge converters. Therefore, it proposes a time-domain approach to model the dynamics of multiwinding transformer-based multilevel dc/dc converter, including self-balancing. In previous research, multiwinding transformers have been modeled using average-based power transfer models. These models, while simple, have no direct intuit
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A novel family of symmetric squaramide-based LMWGs has been synthesised, functionalized with both dansyl moieties and alkyl chain spacers of different lengths (n = 3 and n = 4 named L1 and L2, respectively). L1 and L2 are able to form hydrogels in the DMSO : H2O mixture in different ratios and concentrations. The gels obtained were characterized by means of rheology, TEM and small angle X-ray scat
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The last ten years have seen a sharp increase in externally supported capacity development initiatives for disaster risk management. However, not all of them have generated sustainable results. The purpose of this paper is to scrutinize the current focus on training as the main tool for capacity development in the context of disaster risk management, and to argue for the necessity to address capac
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The neutron-rich nuclei Kr94,96 were studied via projectile Coulomb excitation at the REX-ISOLDE facility at CERN. Level energies of the first excited 2 + states and their absolute E2 transition strengths to the ground state are determined and discussed in the context of the E(21+) and B(E2;21+→01+) systematics of the krypton chain. Contrary to previously published results no sudden onset of defor
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To decide how much resources to spend on reducing mortality risk, governmental agencies in several countries turn to the value of a statistical life (VSL). VSL has been shown to vary depending on the size of the risk reduction, which indicates that WTP does not increase near-proportional in relation to risk reduction as suggested by standard economic theory. Chained approach (CA) is a stated prefe
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The interactions between chelating agents and metal oxide particles play important roles for the distribution and availability of metal ions in aquatic environments. In this work, the adsorption of ethylenediaminetetraacetate (EDTA) onto goethite (alpha-FeOOH) was studied as a function of pH, time, and background electrolyte concentration at 25.0 degrees C, and the molecular structures of the surf
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HbA1C is the stable glucose adduct to the N-terminal group of the beta-chain of HbA0. The measurement of HbA1c in human blood is most important for the long-term control of the glycaemic state in diabetic patients. Because there was no internationally agreed reference method the IFCC Working Group on HbA1c Standardization developed a reference method which is here described. In a first step haemog
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The oscillations between glacial and interglacial climate conditions over the past three million years have been characterized by a transfer of immense amounts of water between two of its largest reservoirs on Earth - the ice sheets and the oceans. Since the latest of these oscillations, the Last Glacial Maximum (between about 30,000 and 19,000 years ago), similar to50 million cubic kilometres of
