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Aim: Examine the effect of a 10 h intervention programme compared with post-mailed minimal intervention (PMMI) given to high-risk alcohol-drinking university freshmen in a random design. Method: In total 693 freshmen at the Lund Institute of Technology, Lund University, Sweden were included in the study. A cognitive behavioural alcohol program (CBAP) or PMMI was given to high-risk drinking freshme

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This paper introduces a model of the atrioventricular node function during atrial fibrillation (AF), and describes the related ECG-based estimation method. The proposed model is defined by parameters that characterize the arrival rate of atrial impulses, the probability of an impulse choosing either one of the two atrioventricular nodal pathways, the refractory periods of these pathways, and the p

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Oestrogen is not only a sex hormone but also an important regulator of the immune system. Expression of the heavy chain of IgM (mu) is essential for B-cell differentiation. However, a small number of IgA-positive B cells can be found in mice lacking the mu chain (mu MT-/-). The aim of this study was to investigate the effects of oestrogen on this alternative B-cell pathway in mu MT-/- mice. Our re

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An activity-based vocabulary for Voice Output Communication Aids (VOCAs) was designed and evaluated through a user-centred, iterative design process, using expressions from the Gothenburg Spoken Language Corpus as well as other recorded, natural conversations. The growth and development of the vocabulary, called Phrases, was closely linked to its evaluation. The iterative design process included p

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Service discovery is central in pervasive middleware systems, built on top of the communication substrate using the more fundamental mechanisms for device discovery. In mobile pervasive systems devices come and go, and switch network frequently, demanding support for device discovery across heterogeneous networks. We present the design of a device discovery mechanism for the PalCom middleware that

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The results of a search for an excited bottom-quark b* in pp collisions at root s = 7 TeV, using 4.7 fb(-1) of data collected by the ATLAS detector at the LHC are presented. In the model studied, a single b*-quark is produced through a chromomagnetic interaction and subsequently decays to a W boson and a top quark. The search is performed in the dilepton and lepton + jets final states, which are c

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Hypoxic preconditioning is thought to rely on gene products regulated by hypoxia-inducible factor (HIF)-1. Here, we show that the HIF-1 target gene cyclin-dependent kinase inhibitor 1, p21(WAF1/CIP1), is essential for neuroprotection by hypoxic/aglycemic or erythropoietin preconditioning using wild-type and p21(WAF1/CIP1)-deficient neurons. Furthermore, overexpression of wild-type p21(WAF1/CIP1) o

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We report the development of a high-level bacterial expression system for the Alzheimer's disease-associated amyloid beta-peptide (A beta), together with a scaleable and inexpensive purification procedure. A beta(1-40) and A beta(1-42) coding sequences together with added ATG codons were cloned directly into a Pet vector to facilitate production of Met-A beta(1-40) and Met-A beta(1-42), referred t

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Rating scales are increasingly the primary outcome measures in clinical trials. However, clinically meaningful interpretation of such outcomes requires that the scales used satisfy basic requirements (scaling assumptions) within the data. These are rarely tested. The SF-36 is the most widely used patient-reported rating scale. Its scaling assumptions have been challenged in neurological disorders

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Following the fragmentation of a 550 MeV u(-1)primary beam of Ni-58, time-and energy-correlated gamma decays from isomeric states in neutron-deficient nuclei in the 1f(7/2) shell have been identified using the GSI fragment separator in combination with the RISING Ge-detector array. The results on isomers in the mirror pairs Ti-43(22)21-Sc-43(21)22 (I-pi = 3/2(+) and 19/2(-)), Cr-45(24)21-Sc-45(21)

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This doctoral thesis explores the implications of establishing tradable certificate schemes for improving energy efficiency (so-called ‘Tradable White Certificate’ [TWC] schemes). Carrying out different case studies, a set of complementary evaluation methods is applied in conducting ex-ante and ex-post evaluation studies. To analyse the attributes and complexities of TWC schemes, the thesis focuse

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We have compared the predictions of ligand-binding affinities from several methods based on end-point molecular dynamics simulations and continuum solvation, i.e. methods related to MM/PBSA (molecular mechanics combined with Poisson-Boltzmann and surface area solvation). Two continuum-solvation models were considered, viz. the Poisson-Boltzmann (PB) and generalised Born (GB) approaches. The non-el

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This paper investigates the gains harvested through base station cooperation in the up-link for a multi-user (MU) Multiple-Input Multiple-Output Orthogonal Frequency Division Multiplexing (MIMO-OFDM) system, operating in a real indoor environment. The base stations perform joint detection using an iterative receiver that carries out multi-user detection and channel estimation via soft information

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A tree-ring-width chronology of Pinus tabulaeformis from Kalaqin, Inner Mongolia was developed using modern dendrochronological techniques. Based on the results of correlation function analysis, the total precipitation from the previous August to current July was reconstructed for 1771-2008 AD with an explained variance of 49.3%. The reconstruction correlated well with the dryness/wetness series d

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The present research is aimed at analyzing spirituality according to the way it is presented in academic management literature. To uncover comprehensively way this phenomenon is described, a thorough scientific analysis of the selected articles was performed including coding the materials, systematically categorizing them as well as critically investigating particular aspects. While conducting the

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Sub-Saharan Africa suffers from a severe infrastructure deficit, particularly in the power sector and this is broadly recognised as a barrier to poverty alleviation, economic growth and sustainable development in the region. At the same time, the region is rich in natural resources and the mining sector, which already makes a significant contribution to national economies is currently expanding an

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This thesis investigates the nonlinear detector response to Laser Induced Phosphorescence signal originating from the CdWO4 phosphor. A matrix method is utilized to map the detectors linearity for decay-time determination as function of detector gain and number of photons reaching the detector. The Matrix is created by scanning the energy of the laser beam hitting the phosphor thus changing the ph