Filtyp
The efficacy of the quadrivalent Human Papillomavirus (HPV) vaccine is thought to be mediated by humoral immunity. We evaluated the correlation between quadrivalent HPV vaccine-induced serum anti-HPV responses and efficacy. 17,622 women were vaccinated at day 1, and months 2 and 6. At day I and at 6-12 months intervals for up to 48 months, subjects underwent Papanicolaou and genital HPV testing. N
Insufficient oxygen and nutrient supply often restrain solid tumor growth, and the hypoxia-inducible factors (HIF) 1 alpha and HIF-2 alpha are key transcription regulators of phenotypic adaptation to low oxygen levels. Moreover, mouse gene disruption studies have implicated HIF-2 alpha in embryonic regulation of tyrosine hydroxylase, a hallmark gene of the sympathetic nervous system. Neuroblastoma
LÖNEAVTAL för tjänstemän Avtal tecknat 2023 Giltighetstid: 2023-05-01–2025-04-30 Akademikerförbunden 1 Innehållsförteckning Löner Unionen ............................................................................... 3 Lokalt löneavtal – Unionen .......................................................... 11 Förhandlingsordning vid lönerevision – Unionen ....................... 17 Löner och förhand
The etiology of type 1 diabetes (T1D) remains unknown, but a growing body of evidence points to infectious agents and/or components of early childhood diet. The National Institutes of Health has established the TEDDY Study consortium of six clinical centers in the United States and Europe and a data coordinating center to identify environmental factors predisposing to, or protective against, islet
Background: Unhealthy diets, the rise of non-communicable diseases, and the declining health of the planet are highly intertwined, where food production and consumption are major drivers of increases in greenhouse gas emissions, substantial land use, and adverse health such as cancer and mortality. To assess the potential co-benefits from shifting to more sustainable diets, we aimed to investigate
BACKGROUND: Lung cancer remains one of the most challenging diseases to treat due to its heterogeneity. Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) mutations are genetic drivers in numerous cancer types including lung adenocarcinoma (LUAD). Despite recent advances in KRAS-targeted therapies, treatment resistance and limited therapeutic options necessitate advanced preclinical models, such as
BACKGROUND: Complement activation may promote atherosclerosis. Yet, data on the to which extent complement, and more specifically the alternative complement pathway, is activated in patients with carotid atherosclerosis and related to adverse outcome in these patients, are scarce.METHODS AND RESULTS: We measured, by ELISA, plasma levels of factor D, properdin, C3bBbP (C3 convertase), and factor H
Svenska, språklig inriktning 1–40 poäng Vårterminen 2024 Litteraturlista för SVEA20, Svenska, språklig inriktning – fortsättningskurs, 30hp Fastställd av sektion 1 vid Språk- och litteraturcentrum den 30 maj 2023. Delkurs 1: Fonetik och fonologi (1,5 hp) Obligatorisk kurslitteratur Delsing, Lars-Olof (1991, rev.1997, 2006, 2017). Fonetikkompendiet. (27 s.) Hämtas ner digitalt enligt lärarens anvis
https://www.sol.lu.se/media/utbildning/dokument/kurser/SVEA20/20241/SVEA20_VT24.pdf - 2026-07-19
Rhesus macaques (RMs) are a vital model for studying human disease and are invaluable to preclinical vaccine research, particularly for the study of broadly neutralizing antibody responses. Such studies require robust genetic resources for antibody-encoding genes within the immunoglobulin (IG) loci. The complexity of the IG loci has historically made them challenging to characterize accurately. To
Proinflammatory diets are associated with risk of developing colorectal cancer (CRC), however, inconsistencies exist in subsite- and sex-specific associations. The relationship between CRC and combined lifestyle-related factors that contribute toward a low-grade inflammatory profile has not yet been explored. We examined the association between the dietary inflammatory potential and an inflammator
Aberrant stem cell-like gene regulatory networks are a feature of leukaemogenesis. The ETS-related gene (ERG), an important regulator of normal haematopoiesis, is also highly expressed in T-ALL and acute myeloid leukaemia (AML). However, the transcriptional regulation of ERG in leukaemic cells remains poorly understood. In order to discover transcriptional regulators of ERG, we employed a quantita
BACKGROUND: Clinical outcome of patients with triple-negative breast cancer (TNBC) is highly variable. This study aims to identify and validate a prognostic protein signature for TNBC patients to reduce unnecessary adjuvant systemic therapy.METHODS: Frozen primary tumors were collected from 126 lymph node-negative and adjuvant therapy-naive TNBC patients. These samples were used for global proteom
The diagnosis of Alzheimer's disease can be improved by the use of biological measures. Biomarkers of functional impairment, neuronal loss, and protein deposition that can be assessed by neuroimaging (ie, MRI and PET) or CSF analysis are increasingly being used to diagnose Alzheimer's disease in research studies and specialist clinical settings. However, the validation of the clinical usefulness o
BACKGROUND: Although rare in the general population, highly penetrant germline mutations in CDKN2A are responsible for 5-40% of melanoma cases reported in melanoma-prone families. We sought to determine whether MELPREDICT was generalizable to a global series of melanoma families and whether performance improvements can be achieved.METHODS: 2,116 familial melanoma cases were ascertained by the inte
BACKGROUND: Abiraterone acetate plus prednisone significantly improved radiographic progression-free survival compared with placebo plus prednisone in men with chemotherapy-naive castration-resistant prostate cancer at the interim analyses of the COU-AA-302 trial. Here, we present the prespecified final analysis of the trial, assessing the effect of abiraterone acetate plus prednisone on overall s
An abstract approach to the Robin–Robin method Emil Engström and Eskil Hansen 1 Introduction The nonoverlapping Robin–Robin method, also known as the optimized Schwarz method with Robin transmission conditions, was introduced in [12] and shown to converge when applied to linear elliptic equations. Since then there have been several theoretical results concerning the method for both nonlinear elli
https://www.maths.lu.se/fileadmin/maths/personal_staff/Eskil_Hansen/EEEHDD28.pdf - 2026-07-19
1 I. CASE OVERVIEW Cynthia A. Villar vs. Alltech Contractors, Inc., et al. (G.R. No. 208702) Country/Region : Republic of the Philippines Forum : Supreme Court of the Philippines Filing Date : 16 March 2012 Status : Decided (Final) Date of Judgement : 11 May 2021 Case Category : Special Civil Action Domestic Laws : Presidential Decree (P.D.) No. 1586 (Philippine Environmental Impact Statement Syst
https://rwi.lu.se/wp-content/uploads/2025/03/Case-Study-Philippines-Villar-v-Alltech.pdf - 2026-07-19
Rättighetslistan - Lunds universitets studenters rättigheter och ansvar Rättighetslistan - Lunds universitets studenters rättigheter och ansvar FASTSTÄLLD AV REKTOR 2020-09-10 Dnr STYR 2017/249 2 Rättighetslistan - Lunds universitets studenters rättigheter och ansvar är beslutad av rektor och ska fungera som stöd för studenterna, institutionerna, fakulteterna och studentkårerna för att klargöra va
https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/Jamstalld/Rattighetslistan-2021-03_PDF.pdf - 2026-06-22
LTH:s 13:e Pedagogiska Inspirationskonferens, 4 december 2025 Abstract— A deck of 67 context cards for Universal Design for Learning (UDL) was developed at four international teacher workshops, to help teachers understand and improve inclusive teaching, i.e. to be proactive and prepared for student diversity. The printed cards have been picked up or ordered by approximately 150 people. This pape
https://www.lth.se/fileadmin/cee/genombrottet/konferens2025/A3_Eftring.pdf - 2026-06-09
