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Background: p21-activated kinase 1 (Pak1) phosphorylates many proteins in both normal and transformed cells. Its ability to phosphorylate and thereby activate the estrogen receptor alpha (ER alpha) potentially limits the effectiveness of antiestrogen treatment in breast cancer. Here we studied associations between Pak1 expression and subcellular localization in tumor cells and tamoxifen resistance
At the time of cancer diagnosis, body mass index (BMI) is inversely correlated with lung cancer risk, which may reflect reverse causality and confounding due to smoking behavior. We used two-sample univariable and multivariable Mendelian randomization (MR) to estimate causal relationships of BMI and smoking behaviors on lung cancer and histological subtypes based on an aggregated genome-wide assoc
CONTEXT: Pancreatic beta-cell glucose sensitivity is the slope of the plasma glucose-insulin secretion relationship and is a key predictor of deteriorating glucose tolerance and development of type 2 diabetes. However, there are no large-scale studies looking at the genetic determinants of beta-cell glucose sensitivity. OBJECTIVE: To understand the genetic determinants of pancreatic beta-cell gluc
Background: Climate change can directly affect human health by varying exposure to non-optimal outdoor temperature. However, evidence on this direct impact at a global scale is limited, mainly due to issues in modelling and projecting complex and highly heterogeneous epidemiological relationships across different populations and climates. Methods: We collected observed daily time series of mean te
Precision nutrition is an emerging concept that aims to develop nutrition recommendations tailored to different people's circumstances and biological characteristics. Responses to dietary change and the resulting health outcomes from consuming different diets may vary significantly between people based on interactions between their genetic backgrounds, physiology, microbiome, underlying health sta
This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy and functional characterization of mouse and human dendritic cells (DC) from lymphoid organs and various nonlymphoid tissues. DC are sentinels of the immune system present in al
Type 2 diabetes (T2D) is caused by insufficient insulin secretion from pancreatic β-cells. To identify candidates contributing to T2D pathophysiology, we studied human pancreatic islets from ~300 individuals. We found 395 differentially expressed genes (DEGs) in islets from individuals with T2D, including, to our knowledge, novel (OPRD1, PAX5, TET1) and previously identified (CHL1, GLRA1, IAPP) ca
Background: Childhood cancer predisposition (ChiCaP) syndromes are increasingly recognized as contributing factors to childhood cancer development. Yet, due to variable availability of germline testing, many children with ChiCaP might go undetected today. We report results from the nationwide and prospective ChiCaP study that investigated diagnostic yield and clinical impact of integrating germlin
AAAL 2023 Colloquium: The ESM in SLA research Saturday, March 18th, 8:00 – 10:00 am AAAL 2023 Colloquium Information The Experience Sampling Method in SLA research: Opportunities and challenges The Experience Sampling Method (ESM; also Ecological Momentary Assessment or Diary Methods) is an intensive data collection approach which involves repeatedly prompting research participants to answer short
https://laminate.ht.lu.se/fileadmin/user_upload/laminate/AAAL_2023_ESM_Colloquium_Schedule.pdf - 2026-06-29
Microsoft Word - 13_KansWilliamsson.doc LTHs 7:e Pedagogiska Inspirationskonferens, 30 augusti 2012 Abstract—In enterprises we find many complex processes consisting of several sub-processes and actors, each of them contributing to the end outcome. Teaching on complex processes is not easy if the aim is deep knowledge regarding the processes and how different activities and choices will affect the
https://www.lth.se/fileadmin/lth/genombrottet/konferens2012/28_Kans_Williamsson.pdf - 2026-06-09
Harris-ILL12 Chiastic iconicity Randy Harris Linguistics, Rhetoric, and Communication Design Department of English University of Waterloo Chiastic iconicity 1. Preliminaries 2. Chiastic suite 3. Symmetry 4. Symmetry and parallelism 5. Balance 6. Meaning AB BA raha@uwaterloo.ca, 2 Preliminaries ABBAX all for one one for all raha@uwaterloo.ca, 3 Preliminaries raha@uwaterloo.ca, 4 The chiastic suite
https://konferens.ht.lu.se/fileadmin/user_upload/conference/ill-12/Harris-ILL12.pdf - 2026-07-04
On the Swedish så-construction Working Papers in Scandinavian Syntax 85, 37-63 The Swedish så-construction, a new point of departure Jackie Nordström Centre for Languages and Literature, Lund University ABSTRACT The following article treats the Swedish så-construction (involving the so-called “adjunctive” så). The så-construction consists of a first element, which is typically an adjunct, followed
https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/WPSS_85_Nordstroem.pdf - 2026-07-04
Postal address Box 117, 221 00 Lund Visiting address LUX, Bldg. B, Helgonavägen 3 Telephone +46 46 222 83 15 Email kristina.arnrup_thorsbro@kansliht.lu.se Website www.ht.lu.se Facul ty Board ’s work ing commit tee General syllabus for third-cycle studies for the Degree of Doctor in East and South-East Asian Studies This syllabus was approved by the Board of the Joint Faculties of Humanities and Th
Rule of Law and Access to Justice - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Progra
https://rwi.lu.se/fair-efficient-justice/ - 2026-07-04
Arbetsprocess examensarbete för kandidatutbildning i livsmedelsteknik | exjobb_externa Hoppa till huvudinnehåll Den här webbplatsen använder cookies för att förbättra användarupplevelsen. Genom att fortsätta använda webbplatsen samtycker du till att cookies används enligt vår cookie-policy (på LTH:s webbplats) . Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera
Center for Mathematical Sciences Division of Mathemat ics and Numerica l Analysis Course Analysis for NUMA41 Numerical Analysis – Basic Course, term HT2022 Course Information Lecturer: Robert Klöfkorn Teaching assistants: Johannes Kasimir Number of students: 15 newly registered and 6 re-registered. 4 students answered the course evaluation, all of of them are enrolled in the Mathematics program. E
https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/HT2022/NUMA41HT22.pdf - 2026-07-04
In Solidarity with the Universities of Ukraine: Engaging in Human Rights Education - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic
https://rwi.lu.se/blog/after-human-rights-violations-in-ukraine-the-building-of-knowledge-that-just-cant-wait/ - 2026-07-04
"A crisp proposal" is requested during Almedalen talk on semiconductors Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen
https://www.lth.se/article/a-crisp-proposal-is-requested-during-almedalen-talk-on-semiconductors/ - 2026-07-05
Promoting Gender Equality Methods, results and lessons learned Introduction The Raoul Wallenberg Institute of Human Rights and Humanitarian Law is deeply ro- oted in the field of gender equality promotion. The Institute seeks to address human rights and gender equality together, concentrating on their common and complimentary as- pects. This approach comes from an under- standing that gender equal
https://rwi.lu.se/app/uploads/2017/06/Gender-Equality-Brief.pdf - 2026-07-05
