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Organ segmentation on magnetic resonance (MR) images for dose planning on cancer patients is a time consuming process that can be automatized by using convolutional neural networks (CNNs). MR images vary greatly in characteristics across acquisition sites, which affects CNN segmentation performance. In this master thesis, augmentation methods were tested and implemented to increase the robustness

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Mental health disorders are a rapidly growing public health problem. Despite the fact that lack of trust in the health-care system is considered to be an important determinant of health, there is scarcity of empirical evidence demonstrating its associations with health outcomes. This is the first study which aims to evaluate the association between trust in the health-care system and psychological

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Greenhouses and nursery-gardens is an important business in Sweden, covering a land area of 3,0 million square meters in 2011. The downside of this otherwise blooming business is however the use of so called PPPs, plant protection products, which is connected to it. Historically the use of PPPs has been widespread and the handling has been conducted in an off-hand way. During the post-war time the

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Background: Targeted temperature management (TTM) is recommended following cardiac arrest; however, time to target temperature varies in clinical practice. We hypothesised the effects of a target temperature of 33 °C when compared to normothermia would differ based on average time to hypothermia and those patients achieving hypothermia fastest would have more favorable outcomes. Methods: In this p

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Land-use and land-cover (LUC) changes are a key uncertainty when attributing changes in measured atmospheric CO2 concentration to its sinks and sources and must also be much better understood to determine the possibilities for land-based climate change mitigation, especially in the light of human demand on other land-based resources. On the spatial scale typically used in terrestrial ecosystem mod

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Shortcomings of current techniques used for the intracerebral transplantation of ventral mesencephalic dopamine neurons include low graft survival, high variability, considerable implantation trauma and suboptimal graft integration. In order to overcome these limitations, we have adopted a microtransplantation approach which allows precise and reproducible implantation of ventral mesencephalon cel

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Transient cerebral ischemia in normoglycemic animals is followed by a decrease in glucose utilization, reflecting a postischemic cerebral metabolic depression and a reduction in the activity of the pyruvate dehydrogenase complex (PDHC). Preischemic hyperglycemia, which aggravates ischemic brain damage and invariably causes seizure, is known to further reduce cerebral metabolic rate. To investigate

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An energy system that relies on fossil fuel is not sustainable. Emissions, such as carbon dioxide, nitric oxide and corpuscles, affect the climate and pollute the air. Furthermore, the supply of oil, coal and natural gas is located a few places worldwide, which can give provide incentive to geopolitical conflicts for access to these areas. This is not a local issue for Tjörn, nor even a national i

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Objectives: Identification of biological markers that can guide treatment selection is considered to be a viable solution for personalized treatment for patients with psychiatric disorders. This study investigated whether macrophage migration inhibitory factor (MIF) levels at baseline were associated with mindfulness-based group therapy or cognitive behavioral therapy response in patients with mil

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PURPOSE: The DIANA study aimed to evaluate how often antimicrobial de-escalation (ADE) of empirical treatment is performed in the intensive care unit (ICU) and to estimate the effect of ADE on clinical cure on day 7 following treatment initiation.METHODS: Adult ICU patients receiving empirical antimicrobial therapy for bacterial infection were studied in a prospective observational study from Octo

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Objective: Measurement of fetal scalp blood lactate is a supplementary tool to cardiotocography in the case of a non-reassuring tracing. Several hand-held lactate meters have been launched, all with differentials in absolute values. Therefore, the reference intervals must be calculated for each device. The internationally accepted reference interval is based on measurement with Lactate ProTM with

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Background Oxidative stress is implicated in both depression and anxiety, but it is currently unclear whether this relates to syndromal diagnoses or trans-diagnostic dimensional symptoms. We examined the relationship between oxidative stress and severity of depression and anxiety symptoms in individuals with Major Depressive Disorder (MDD). Methods Plasma oxidative stress markers F2-isoprostanes a

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Aim: The Eurasian otter (Lutra lutra) is a flagship species for global freshwater ecosystems. As one of the most widely distributed Palearctic mammals, the otter used to inhabit most provinces in China. However, after decades of relentless hunting and habitat degradation, the Sanjiangyuan Region is now one of last strongholds for this species in China. Currently, there still remains an enormous kn

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Breast cancer screening is predominantly performed using digital mammography (DM), but higher sensitivity has been demonstrated with digital breast tomosynthesis (DBT). A partial DBT screening in selected groups with a clear benefit from DBT might be more feasible than a full implementation, and using artificial intelligence (AI) to select women for DBT might be a possibility. This study used data

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The thesis is a collection of four papers on Greek street art (specifically situated in the city of Athens) with a focus on metaphors and narratives. The overall aim guiding this thesis is to explore how street art in times of crisis can represent sociopolitical issues and in what ways these messages can be conveyed. By using the perspective of cognitive semiotics to address this, a parallel aim i

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This guide presents a joint effort of projects funded under the European Research Area for Climate Services (ERA4CS) (http://www.jpi-climate.eu/ERA4CS), a co- funded action initiated by JPI Climate with co-funding by the European Union (Grant 690462), 15 national public Research Funding Organisations (RFOs), and 30 Research Performing Organisations (RPOs) from 18 European countries. This guide set

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Under de senaste 150 åren har det svenska landskapet genomgått mycket stora förändringar. Det har lett till förlust av livsmiljöer för många arter och har haft långtgående konsekvenser för vår inhemska fauna och flora. Många arter har minskat dramatiskt och i vissa fall helt försvunnit.När en art väl har börjat minska finns det många faktorer som kan förstärka den negativa trenden. En individrik p