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Background: Speech impairments are an early feature of Alzheimer’s disease (AD) and consequently, analysing speech performance is a promising new digital biomarker for AD screening. Future clinical AD trials on disease modifying drugs will require a shift to very early identification of individuals at risk of dementia. Hence, digital markers of language and speech may offer a method for screening
There is an increasing interest in understanding the atomic level formation of functional materials, e.g. through nucleation and growth from their precursors in solution or through chemically induced phase transitions. Such information is achievable though synchrotron-based in situ X-ray absorption spectroscopy (XAS) and total scattering (TS) experiments. In this study we present a new and versati
Promoting longer lifetimes and efficient re-use of products has a significant potential to save resources and reduce adverse environmental impacts, especially for products that have large resource footprints related to extraction and production processes, as for instance automobiles. Remanufacturing is a product life extension strategy promoting the effective and efficient re-use of products by re
More and more things are getting connected to the internet, including lights, speakers, and refrigerators. These connected things are an example of what a smart home system that is part of the Internet of Things (IoT) can incorporate. IoT enables advanced services by interconnecting physical and virtual things. But, building interactive prototypes for smart home systems can be difficult and costly
The present work describes the numerical modeling of medium-speed marine engines, operating in a fumigated dual-fuel mode, i.e. with the second fuel injected in the ports. This engine technology allows reducing engine-out emissions while maintaining the engine efficiency and can be fairly easily retrofitted from current diesel engines. The main premixed fuel that is added can be a low-carbon one a
Researchers trialing behavioral interventions often use attention control groups, but few publish details on attention control activities or perceived benefit. Attention control groups receive the same dose of interpersonal interaction as intervention participants but no other elements of the intervention, to control for the benefits of attention that may come from behavioral interventions. Becaus
This paper focuses on the specific problems in the labour and social security legislation as it relates to crowdworkers in the digitalizes new economy, analyzing their place in labour market, and especially in the collective agreements which are the standard means of regulating working conditions in the Nordic model. Sweden has a binary system where a performing party is as either an employee or s
The environmental and food contaminant, benzo[a]pyrene {B[a]P, a polycyclic aromatic hydrocarbon (PAH)}, is classified as a human carcinogen by the International Agency for Research on Cancer. The carcinogenicity of B[a]P is linked to the formation of electrophilic metabolites, namely B[a]P-diol epoxides (BPDEs) occurring as stereoisomers. In this work, we quantified the metabolic formation of BPD
Aim: To evaluate person-centeredness in nursing homes from the perspective of frail older persons, before and after implementing an educational intervention about palliative care. Design: A crossover design. Methods: Forty-four older persons living in nursing homes were interviewed. A convergent mixed-method was used to analyse data. Results: The older persons expressed feelings of unsafety relate
Hippocampal subfield segmentation on in vivo MRI is of great interest for cognition, aging, and disease research. Extant subfield segmentation protocols have been based on neuroanatomical references, but these references often give limited information on anatomical variability. Moreover, there is generally a mismatch between the orientation of the histological sections and the often anisotropic co
We present GlassesViewer, open-source software for viewing and analyzing eye-tracking data of the Tobii Pro Glasses 2 head-mounted eye tracker as well as the scene and eye videos and other data streams (pupil size, gyroscope, accelerometer, and TTL input) that this headset can record. The software provides the following functionality written in MATLAB: (1) a graphical interface for navigating the
Multiple facile synthetic strategies for all inorganic perovskite CsPbBr3 nanocrystals (NCs) have been established and developed, profiting from their excellent performance and great potential applied in the field of photonic and optoelectronic. Here, CsPbBr3 NCs were synthesized by both hot injection method (method 1) and conversion method (method 2), and the discrepancy of their photophysical pr
Ignition and extinction characteristics of a material determine whether a fire will be initiated and grow. In fire safety engineering, where modellers deal with a multitude of materials, simplified thresholds are commonly used to determine when ignition and extinction occur.Such a threshold is the critical mass flux, which describes when sufficient fuel vapour is produced to support sustained flam
Epilepsy is a neurological disorder, affecting approximately 1% of the population. The high rate of drug-resistance in epilepsy in general (30%), and temporal lobe epilepsy (TLE) in particular, pose a serious clinical problem. Thus, novel treatments for drug-resistant epilepsy is highly warranted. Gene therapy has been suggested to be a promising approach to target drug-resistant focal epilepsy si
Background: Demography, politics, economy, and governance appear to be the major structural factors for health and well-being. These factors have a significant role to play in achieving universal health coverage (UHC). The majority of previous studies did not highlight those factors. The aim of this study is to explore the basic structural factors (political stability, demography, gross national i
