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Physiologically based pharmacokinetic (PBPK) models offer the ability to simulate and predict the biodistribution of radiopharmaceuticals and have the potential to enable individualised treatment planning in molecular radiotherapy. The objective of this study was to develop and implement a whole-body compartmental PBPK model for peptide receptor radionuclide therapy (PRRT) with [177Lu]Lu-DOTA-TATE
Aim: Previous research has indicated that preoperative beta blocker therapy is associated with a decreased risk of complications after surgery for rectal cancer. This is thought to arise because of the anti-inflammatory activity of the drug. These results need to be reproduced and analyses extended to other drugs with such properties, as this information might be useful in clinical decision-making
Background: The Critical Assessment of Genome Interpretation (CAGI) aims to advance the state-of-the-art for computational prediction of genetic variant impact, particularly where relevant to disease. The five complete editions of the CAGI community experiment comprised 50 challenges, in which participants made blind predictions of phenotypes from genetic data, and these were evaluated by independ
Background: Histological grade is a well-known prognostic factor that is routinely assessed in breast tumours. However, manual assessment of Nottingham Histological Grade (NHG) has high inter-assessor and inter-laboratory variability, causing uncertainty in grade assignments. To address this challenge, we developed and validated a three-level NHG-like deep learning-based histological grade model (
Background: During the COVID-19 pandemic, the majority of patients received ambulatory treatment, highlighting the importance of primary health care (PHC). However, there is limited knowledge regarding PHC workload in Europe during this period. The utilization of COVID-19 PHC indicators could facilitate the efficient monitoring and coordination of the pandemic response. The objective of this study
Over the last 50 years, there has been significant development of qualitative research and related methods in healthcare. Theoretical frameworks support researchers in selecting appropriate research approaches, procedures and analytical tools. However, the implications of the choice of theory are sparsely elucidated. Based on a text excerpt from a public debate article, the study aimed to show how
Bidirectional Low Temperature Networks (BLTNs) are an innovative technology of district heating and cooling systems. Because of their intrinsic feature of supplying simultaneous heating and cooling either directly from an energy source/sink or through distributed heat pumps and chillers, circulation pumps installed at each building extract water from the network and a distinct pressure cone is sub
BACKGROUND: In the European Union alone, more than 100 million people present to the emergency department (ED) each year, and this has increased steadily year-on-year by 2-3%. Better patient management decisions have the potential to reduce ED crowding, the number of diagnostic tests, the use of inpatient beds, and healthcare costs.METHODS: We have established the Skåne Emergency Medicine (SEM) co
Older adults have multiple medical and social care needs, requiring a shift toward an integrated person-centered model of care. Our objective was to describe and summarize Swedish experiences of integrated person-centered care by reviewing studies published between 2000 and 2023, and to identify the main challenges and scientific gaps through expert discussions. Seventy-three publications were ide
Alternative fuels, such as natural and bio-gas, are attractive options for reducing greenhouse gas emissions from combustion engines. However, the naturally occurring variation in gas composition poses a challenge and may significantly impact engine performance. The gas composition affects fundamental fuel properties such as flame propagation speed and heat release rate. Deviations from the gas co
Overuse of antibiotics is accelerating the antimicrobial resistance among pathogenic microbes which is a growing public health challenge at the global level. Higher resistance causes severe infections, high complications, longer stays at hospitals and even increased mortality rates. Antimicrobial resistance (AMR) has a significant impact on national economies and their health systems, as it affect
We have previously described a new series of selective and orally available galectin-1 inhibitors resulting in the thiazole-containing glycomimetic GB1490. Here, we show that the introduction of polar substituents to the thiazole ring results in galectin-1-specific compounds with low nM affinities. X-ray structural analysis of a new ligand-galectin-1 complex shows changes in the binding mode and l
Frontotemporal dementia (FTD) is the second most common cause of early-onset dementia after Alzheimer disease (AD). Efforts in the field mainly focus on familial forms of disease (fFTDs), while studies of the genetic etiology of sporadic FTD (sFTD) have been less common. In the current work, we analyzed 4,685 sFTD cases and 15,308 controls looking for common genetic determinants for sFTD. We found
Citizens have increasingly diversified their use of social media platforms, raising questions about which platforms are adopted and for what purposes. We use survey data from four countries (Canada, France, the United States, and the United Kingdom) gathered in 2019 and 2021 (n = 12,302) about Facebook, YouTube, Instagram, Twitter, Reddit, Snapchat, and WhatsApp. Political ideology predicts the ad
Neurosjukvard.indd Neurosjukvård AVANCERAD NIVÅ, 15HP Institutionen för hälsovetenskaper erbjuder utbildningar som genomförs av lärare vid Lunds universitet och i många fall i samarbete med arbetslivet - en garanti för både ämnesmässig bredd och aktualitet, ett vetenskapligt djup och en modern pedagogik. Institutionens uppdragsverksamhet sker i samarbete med Lund University Commissioned Education
https://www.medicin.lu.se/sites/medicin.lu.se/files/neurosjukvard_h19.pdf - 2026-07-09
HT2014 – VT2015 Kursanalys MSFM31 Medicinsk strålningsfysik – klinisk praktik och lagstiftning Lena Jönsson Beskrivning av delkursen Kursen består av fyra praktikperioder under vardera tre veckor. Tidigare har studenterna gjort hela sin praktik antingen i Lund eller i Malmö. Från och med hösten 2012 har studenterna fått studenterna fått delta i verksamheterna i både Lund och Malmö samt även göra k
Lunds University Master's Programme in Environmental Science P.O. BOX 174 - 8-22100 _Lund, 8weden - TEL: +46 46 222 04 70 - FAX +46 46 222 04 75 E-MAIL: lumes@envir.lu.se - INTERNET: http:// www.lumes.lu.se An EIA study on the "Sundabraut" project in Reykjavik, leeiand Master' s thesis Mars 2000 By Magnus Björnsson Supervisor: Janusz Niemczynowicz, PhD Department ofWater ResourcesEngineering List
https://www.lumes.lu.se/sites/lumes.lu.se/files/bjornsson_magnus.pdf - 2026-07-09
Summary Sheet – Master's programme in Nanoscience Admissions for 2023 1/6 Summary Sheet – Master’s programme in Nanoscience Admissions for 2023 Questions? Please check out FAQ on: www.lth.se/english/faq Here you can also find guidelines on how to convert local credits into ECTS. Personal information (same as your universityadmissions.se account) First name Last name Application number Email State
https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2022-10/Summary%20Sheet%20Nanoscience.pdf - 2026-07-09
Lund 2019-09-24 Hur ska man bo när pensionen är låg? Vi på Lunds universitet söker deltagare till en forskningsstudie om boende bland äldre som har låg pension. Antalet personer över 65 som har en pension under 12.100 kr/månad ökar oroväckande. Dvs. under relativa fattigdomsgränsen. I media har det bland annat framkommit att äldre som bor i villa har svårt att få lån på banken för att renovera. De
