Filtyp
Background Lactobacillus reuteri converts glycerol to 3-hydroxypropionic acid (3HP) and 1,3-propanediol (1,3PDO) via 3-hydroxypropionaldehyde (3HPA) as an intermediate using enzymes encoded in its propanediol-utilization (pdu) operon. Since 3HP, 1,3PDO and 3HPA are important building blocks for the bio-based chemical industry, L. reuteri can be an attractive candidate for their production. However
FKBP12 serves a dual role as a peptidyl-prolyl cis-trans isomerase and as a modulator of several cell signaling pathways. The macrolide FK506 is a transition-state analog of the catalyzed reaction and displaces FKBP12 from its natural target proteins. We compared the conformational exchange dynamics of the backbone and methyl-bearing side chains of FKBP12 in the free and FK506-bound states using N
OBJECTIVES: This is the first nationwide study with the aim to analyze whether there is an association between country of birth in first-generation immigrants and hospitalization for type 2 diabetes (T2D), and to study whether any such association remains in second-generation immigrants. DESIGN: In this follow-up study, the Swedish Hospital Discharge Register was used to identify all hospital
The term gastrointestinal neuromuscular disease describes a clinically heterogeneous group of disorders of children and adults in which symptoms are presumed or proven to arise as a result of neuromuscular, including interstitial cell of Cajal, dysfunction. Such disorders commonly have impaired motor activity, i.e. slowed or obstructed transit with radiological evidence of transient or persistent
In this work the synthesis of waterborne polyurethane/nanosilica nanocomposites by using two differ-ent strategies is presented, starting from a vinyl terminated polyurethane prepolymer (PUP) based onisophorone diisocyanate and polypropylene glycol, and varying the nanosilica content. In one case, thePUP was dispersed in an aqueous solution containing glycerol-functionalized colloidal nanosilica p
Background: Mass screening for celiac disease (CD) as a public health intervention is controversial. Prior to implementation, acceptability to the targeted population should be addressed. We aimed at exploring adolescents' and parents' experiences of having the adolescents' CD detected through mass screening, and their attitudes towards possible future mass screening. Methods: All adolescents (n =
Objective To determine coverage and generalisability of data in the Swedish Biologics Register ARTIS. Methods Patients with adult onset rheumatoid arthritis (RA) were identified in the National Patient Register and the Swedish Rheumatology Quality Register, including the ARTIS cohort of patients exposed to biological agents. Exposure to etanercept and adalimumab between 2006 and 2008 was determine
The aim was to investigate whole-body and red marrow absorbed doses in treatments of neuroblastoma (NB) and adult neuroendocrine tumors (NETs) with (131)I-metaiodobenzylguanidine and to propose a simple method for determining the activity to administer when dosimetric data for the individual patient are not available.
New basis sets of the atomic natural orbital (ANO) type have been developed for the lanthanide atoms La-Lu. The ANOs have been obtained from the average density matrix of the ground and lowest excited states of the atom, the positive ions, and the atom in an electric field. Scalar relativistic effects are included through the use of a Douglas-Kroll-Hess Hamiltonian. Multiconfigurational wave funct
The effects of a driver assistance system for keeping safe speed and safe distance (referred to as SASPENCE) on driver behaviour, reactions and acceptance were evaluated in a test carried out in 2006. Twenty test drivers, recruited by ads, drove two times (once with the system off and once with the system on) in real traffic conditions along a 50 km long test route containing urban and rural roads
The main finding of this thesis is that the relevance and influence of Aaron Wildavsky’s book Searching for Safety in today’s safety discourse is limited although Wildavsky may be considered to be the linking pin between RE, HRO and NAT. The safety discourse may benefit from Wildavsky’s work in political science: I.e., dealing with social power within organizations, the use of net benefit in risk
To achieve established climate objectives, Sweden must effectively target its carbon-intensive steel industry. This study offers a social perspective on the Swedish steel industry's decarbonization, exploring how workers’ identities shape their experience of the transition. Social identity theory is utilised to explore what elements shape steelworkers’ collective and occupational identities in
Artificial intelligence (AI) technologies are being widely employed globally to enhance marine safety services and address challenges within the maritime sector. Nevertheless, the provision of these services in East Africa, particularly within the Lake Victoria basin, is deficient and inadequate. Consequently, a study needs to be undertaken to pinpoint certain domains in marine safety that may be
Due to the intensifying impacts of climate change, accurate estimation of global carbon stocks is crucial, with aboveground vegetation biomass representing a significant carbon reservoir. Savannahs, which cover approximately 50% of the African continent, play a vital role in carbon storage, as trees within these ecosystems contribute substantially to the continent’s total carbon stocks. Estimating
The design of the cost model is motivated by the need of the customer to optimize its energy consumption and maximize the savings. Therefore, this tool will be able to manage the data from both power (geothermal heat pumps) and heating (district heating) systems, as well as outdoor temperatures, energy demand and other inputs, and determine which one is more feasible for every hour of the year. Al
This thesis investigates the ecological and urban regeneration of the Svisloch River in Minsk, focusing on its central urban segment. Historically a natural watercourse and public axis, the Svisloch has undergone a significant transformation into a technically regulated water body, reflecting the city's changing priorities as a result of Soviet-era infrastructure development and contemporary u
Satellite remote sensing is a powerful tool for modelling gross primary production (GPP) at large scales. While model comparison is a prerequisite for understanding carbon dynamics comprehensively, existing GPP products rely on a limited number of satellite sensors. In this study, the contemporary fraction of absorbed photosynthetically active radiation product derived from PROBA-V and Sentinel-3
Introduction: Side-stream residue, oat okara, from the oat-milk production contains valuable nutrients but possesses a high risk of microbial spoilage. Valorisation of oat okara is therefore important to make sure that the oat beverage production stays sustainable. In this project, High-pressure processing (HPP), heat treatment and Lactobacillus fermentation have been evaluated for their microbial
