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Neural transplantation is an experimental treatment for Parkinson's disease. Widespread clinical application of the grafting technique is hampered by a relatively poor survival (around 10%) of implanted embryonic dopamine neurones. Earlier animal studies have indicated that a large proportion of the grafted cells die during graft tissue preparation and within the first few days after intracerebral
A nasal spray formulation containing an extract of Artemisia abrotanum L. was developed for therapeutic use in patients with allergic rhinitis and other upper airway disorders. The nasal spray preparation used contains a mixture of essential oils (4 mg/ml) and flavonols (2.5 mug/ml), of which some components have been shown to possess antiinflammatory, expectorant, spasmolytic as well as antisepti
In adult soft tissue sarcoma (STS) of the extremities and trunk wall, improved prognostic factors are needed to identify patients at high-risk for metastasis. Various factors are included in the many prognostic systems currently in use and the prognostic value of immunohistochemical (IHC) expression of biological markers is unclear. The tissue-preserving, high throughput tissue microarray (TMA) te
Popular Abstract in Swedish Syftet med denna studie är att förbättra den nuvarande svenska konflikttekniken [TCT] inom området fordon - fotgängarekonflikter. Den nuvarande definitionen av konflikters allvarlighetsgrad verkar ge färre allvarliga konflikter än den borde, särskilt när den relevanta trafikanten (RRU) är en fotgängare. Ett annat mål är att tillämpa den svenska konflikttekniken i JordanThis study is aimed at improving the current Swedish Traffic conflicts Technique [TCT] in relation to vehicle-pedestrian conflicts. The present definition of conflict severity appears to produce less severe conflicts than they might be, particularly if the relevant road user (RRU) is the pedestrian. Another aim is to apply the Swedish TCT in Jordan as a method for evaluating safety conditions at j
The affinity and enantioselectivity have been determined for designed propranolol derivatives as ligands for Cel7A by capillary electrophoresis (CE) at pH 7.0. These results have been compared to measurements at pH 5.0. In agreement with previous studies, the affinity increased at the higher pH. However, the affinity was not as dependent of the ligand structure at pH 7.0 as at pH 5.0, and the sele
Sixty-two patients with lymphoedema of the arm after mastectomy and with hypertrophy of the adipose tissue were consecutively treated by liposuction in three different ways. The first group was operated on without the use of a tourniquet. In the second group, liposuction extended up to the distal edge of the tourniquet, and then into the proximal upper arm previously covered by the tourniquet usin
A method for determining the placement of x-ray absorption data into an experimental density of states for an adsorbate-semiconductor system is motivated and illustrated with the cases of bi-isonicotinic acid, isonicotinic acid, and benzoic acid on rutile TiO2(110). Special attention is paid to experimental aspects, as well as the role of Z+1 effects and the choice of reference level.
Results are reported for biosensors based on two different preparations of the same enzyme, laccase from Cerrena unicolor, one lyophilized and one stored frozen at - 18degreesC, for monitoring phenolic compounds. The enzyme was adsorbed on graphite electrodes and these were used in a flow through wall jet cell connected to a flow injection set-up. The electrodes were used at - 50 mV vs. AgAgCl. Th
The effect of mixing time on wheat protein composition and gluten formation was studied for three commercial flour mixtures (biscuit, standard and strong) and one durum flour. Ultracentrifugation was used to separate the fresh, wet gluten from the wheat-flour dough immediately after mixing. Small deformation dynamic theological measurements and RP- and SE-HPLC were used to determine the characteri
The thesis deals with determination of the post peak behaviour of wood in pure tension and pure shear. Furhermore, the "Fictitious Crack Model" (FCM), which is a nonlinear fracture mechanics model ; originally developed for description of crack propagation in concrete, is employed to demonstrate the advantages of non linear fracture mechanics. A testing arrangement is presented with which the comp
The lateral ganglionic eminence (LGE) is known to give rise to striatal projection neurons as well as interneurons, which migrate in the rostral migratory stream (RMS) to populate the granule cell and glomerular layers of the olfactory bulb. Because all of these neuronal subtypes express Distalless-related (DLX) homeobox proteins during their differentiation, we set out to further characterize pro
New methods for spectrophotometric alkalinity measurement, dissolved hydrogen monitoring and for obtaining a fingerprint of the microbial community were evaluated as tools for process monitoring in anaerobic digestion. The anaerobic digestion process was operated at organic loading rates of 1.5, 3.0 and 4.5g volatile solids l-1d-1 and subjected to pulse loads of carbohydrate, lipid, protein and a
Background Open abdomen (OA) treatment often results in difficulties in closing the abdomen. Highest closure rates are seen with the vacuum-assisted wound closure (VAWC) technique. However, we have experienced occasional failures with this technique in cases with severe visceral swelling needing longer treatment periods with open abdomen. Feasibility and short-term outcome of a novel combination o
Detergent/polymer aqueous two-phase systems are studied as a fast, mild and efficient general separation method for isolation of labile integral membrane proteins. Mechanisms for phase behaviour and protein partitioning of both membrane-bound and hydrophilic proteins have been examined in a large number of detergent/polymer aqueous two-phase systems. Non-ionic detergents such as the Triton series
Activity quantification in nuclear medicine imaging is highly desirable, particularly for dosimetry and biodistribution studies of radiopharmaceuticals. Quantitative In-111 imaging is increasingly important with the current interest in therapy using Y-90 radiolabeled antibodies. One of the major problems in quantification is scatter in the images, which leads to degradation of image quality. The a
A search for squarks and gluinos in final states containing high-pT jets, missing transverse momentum and no electrons or muons is presented. The data were recorded in 2012 by the ATLAS experiment in root s = 8 TeV proton-proton collisions at the Large Hadron Collider, with a total integrated luminosity of 20.3 fb(-1). Results are interpreted in a variety of simplified and specific supersymmetry-b
