Filtyp
Since a tightly regulated complement system is needed for a successful pregnancy, we hypothesized that alterations in complement inhibitors may be associated with idiopathic, recurrent miscarriage. We sequenced all exons coding for three complement inhibitors: C4b-binding protein (C4BP), CD46 and CD55 in 384 childless women with at least two miscarriages that could not be explained by known risk f
We have investigated methods of starch dissolution with the aim of finding an optimum method to completely dissolve starch granules to form a molecularly dissolved starch solution without degradation of the polymers. Glycogen was used as a model molecule for amylopectin, to identify the dissolution conditions under which the degradation of the polymers was limited or not present. Dissolution was p
A search for direct production of supersymmetric gauginos and sleptons in final states with two and three leptons is presented. The two lepton analysis uses 4.7 fb(-1) of proton-proton collision data at root s = 7 TeV, while the three lepton analysis uses 13 fb(-1) at root s = 8 TeV. All data were recorded by the ATLAS detector at the Large Hadron Collider. The results are interpreted in the pheno
Macro and micronutrient deficiencies are a significant problem among people in rural areas in developing countries. Deficiencies may lead to an impaired immune system making the organism vulnerable to infections and diseases. In this paper, the dietary intake, anthropometric measurements, zinc and copper levels in serum, of patients with cutaneous leishmaniasis (CL) are compared with a group of he
This paper presents a 1MHz bandwidth, ΔƩ fractional-N PLL as the frequency synthesizer for LTE. A noise cancellation path composed of a novel hybrid ΔƩ DAC with 9 output bits is incorporated into the PLL in order to cancel the out-of-band phase noise caused by the quantization error. Further, a re-timing circuit is proposed to reduce the nonlinearity in the Charge Pump and provide pulse shaping si
Most wastewater treatment plants contain an activated sludge process, which consists of a biological reactor and a sedimentation tank. The purpose is to reduce the incoming organic material and dissolved nutrients (the substrate). This is done in the biological reactor where micro-organisms (the biomass) decompose the substrate. The biomass is then separated from the water in the sedimentation tan
BACKGROUND: Optimal treatment of soft-tissue sarcoma requires multidisciplinary management at a sarcoma center. However, these rare tumors are often misinterpreted as benign and many are inadequately treated outside a sarcoma center, with an increased risk of local recurrence that often requires further extensive surgical treatment. To improve referral and centralization of soft-tissue sarcoma man
We carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry. We find genetic variants at 12 new loci to be associated with blood pressure (P = 3.9 × 10(-11) to 5.0 × 10(-21)). The sentinel blood pressure SNPs are enriched for association with DNA methylation at multiple n
An economically sustainable process was developed for propionic acid production by fermentation of glycerol using Propionibacterium acidipropionici and potato juice, a by-product of starch processing, as a nitrogen/vitamin source. The fermentation was done as high-cell-density sequential batches with cell recycle. Propionic acid production and glycerol consumption rates were dependent on initial b
This study aims to evaluate the direct effects of anthropogenic deforestation on simulated climate at two contrasting periods in the Holocene, similar to 6 and similar to 0.2 k BP in Europe. We apply We apply the Rossby Centre regional climate model RCA3, a regional climate model with 50 km spatial resolution, for both time periods, considering three alternative descriptions of the past vegetation
Cloud computing has recently received considerable attention, as a promising approach for delivering ICT services by improving the utilisation of data centre resources. On the other hand, the increased usage of ICT, jointly with the increased cost of energy, make designing and managing data centres with energy efficient strategies a crucial and strategical problem. In the literature there are man
In this chapter, we focus on one element of the fragmentation of global climate governance, namely the overlap between the UN climate regime and the World Trade Organization (WTO). With a view to the appraisal question for the ‘architecture’ theme of this volume, we hold that this overlap not only implies benefits, but may also entail significant drawbacks for the development and implementation of
Glass sheets investigated regarding their Po-210 signal originating from indoor radon exposure will have a depth distribution down to about 100 nm. The geometrical probability of implantation into glass of glass-attached radon daughter activity in one alpha recoil event is 50%. A particulate layer on the glass sheet (dust, grease or other particles) will stop the alpha recoil nucleus partly or tot
The author spent seven years teaching and tutoring basic media use to liberal arts students. During this time, the author noted that liberal arts students differ in their use of technology, both in basic technical comprehension and computer skills levels, as compared to technical and computer science students. Different pedagogical approaches for the liberal arts students for the period of 2003-20
Increasing evidence supports the benefit of identifying BRCA1 and BRCA2 germline mutations in early breast cancer. Selection of patients for genetic testing is based on defined criteria taking individual and family history related factors into account. It is important to make a distinction between efficacy and effectiveness of BRCA testing criteria. Efficacy can be defined as the performance under
Although they are often subjected to critical scrutiny, formal geopolitical practices have rarely been put on trial. One exception is the case of Gudmund Hatt (1884-1960), professor of human geography at Copenhagen University from 1929 to 1947, who was found guilty of “dishonorable national conduct” for his geopolitics during the German occupation. As a contribution to the critical history of geop
