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A search for heavy neutral Higgs bosons produced in association with one or two b-quarks and decaying to b-quark pairs is presented using 27.8 fb-1 of s=13 TeV proton-proton collision data recorded by the ATLAS detector at the Large Hadron Collider during 2015 and 2016. No evidence of a signal is found. Upper limits on the heavy neutral Higgs boson production cross section times its branching rati
Background: Unresectable disease is sometimes diagnosed during surgery in patients with pancreatic ductal adenocarcinoma (PDAC). This study aimed to identify preoperative risk factors for metastatic disease diagnosed at surgical exploration and to investigate and compare survival in resected and non-resected patients. Methods: Patients were identified from the Swedish National Pancreatic and Peria
Few studies have investigated the real-life outcomes of interdisciplinary multimodal pain rehabilitation programs (IMMRP) for chronic pain. This study has four aims: investigate effect sizes (ES); analyse correlation patterns of outcome changes; define a multivariate outcome measure; and investigate whether the clinical self-reported presentation pre-IMMRP predicts the multivariate outcome. To thi
Background: Virtual Reality cognitive behavioral therapy (VR-CBT) has proven to be an effective treatment method for paranoia and anxiety in psychosis. However, it is unknown, which individuals benefit most from VR-CBT. Previous studies examined factors affecting the treatment effect of regular CBTp, including illness duration, paranoia, depression, and pre-therapy avoidance behaviors, but results
Universal screening for defective mismatch repair (dMMR) in colorectal cancer utilizes immunohistochemical staining for MLH1, MSH2, MSH6 and PSM2. Additionally, BRAF V600E mutations status and MLH1 hypermethylation should be performed to distinguish germline and somatic dMMR alterations. A decade of Danish population-based registries has been analysed regarding screening uptake, detection rate and
Warmer temperatures and the combined effects of wind and water erosion leads to serious soil loss. Identifying the contribution of different drivers to wind and water compound erosion can improve soil erosion management in the watershed. Accordingly, we calculated the erosion energy based on energy theory and applied the mutation test and trend analysis to explore environmental drivers, runoff, an
A parent’s life threating illness and death can significantly affect their children's wellbeing in both the short and long term. Support from professionals is recommended when parents lack the ability to help children cope with loss, bereavement, and grief. The overall aim of this dissertation was to illuminate professionals’ encounters with children of a seriously ill or deceased parent and to ex
The need to develop new and computationally efficient artificial intelligence models that accurately simulate river flows in data-scarce regions, considering not only current but also projected future climate change conditions is vital. In this study, a hybrid artificial neural network (ANN) model that combines HEC-HMS and the feed-forward neural network (FFNN) was developed in the Python programm
Outcome under-ascertainment, characterized by the incomplete identification or reporting of cases, poses a substantial challenge in epidemiologic research. While capture-recapture methods can estimate unknown case numbers, their role in estimating exposure effects in observational studies is not well established. This paper presents an ascertainment probability weighting framework that integrates
I denna rapport redovisas populationstrender för 224 svenska fågelarter för olika långa tidsperioder, samt korttidstrender för 13 arter av större däggdjur. Fåglarna har räknats höst, vinter, vår och sommar enligt strikt standardiserade metoder. Sommar- respektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan 1996) men täcker We present the results of the Swedish Bird Survey, a project run by the Department of Biology, Lund University, as a part of the National Monitoring Programme of the Swedish Environmental Protection Agency. The results for 2023 include data from: 517 winter point counts in 2022/2023 (48th winter), of which 243 were carried out during the Christmas/New Year count, 181 summer point count routes (49t
OBJECTIVES: The Apollo study was designed to support the clinical performance verification of the adjusted cutoffs of the Elecsys® β-Amyloid(1-42) (Aβ42) cerebrospinal fluid (CSF) II, β-Amyloid(1-40) (Aβ40) CSF, Phospho-Tau (181P) (pTau) CSF and Total-Tau (tTau) CSF immunoassays (Roche Diagnostics International Ltd) for measuring fresh CSF samples, and assess the concordance of the Elecsys CSF pTa
In food engineering in general and in liquid food processing specifically, accurate measurement of particle size is important, both for product development and daily quality control. Laser diffraction is the dominating method for particle size measurement of e.g., plant cell structures in food and beverage processing. However, the accuracy of the method can be questioned since these particles diff
Introduction: South Africa has one of the highest incidence rates of notified tuberculosis (TB) in the world. Achieving TB control requires strengthening treatment and support services. The implementation of differentiated delivery models can be used to improve service quality and enhance retention in care. This study aimed to identify treatment and support delivery preferences among people on TB
Background: The aim of heart transplantation is prolonged survival and improved quality of life. Chronic pain is a common and distressing symptom after heart transplantation. To our knowledge, there are no person-centred interventions aimed at chronic pain and symptom distress after heart transplantation. The aim was to assess the feasibility and acceptability of systematic, person-centred symptom
Background: Posttraumatic stress disorder (PTSD) and substance use disorders (SUD) frequently co-occur in youth. Integrated, trauma-focused treatments are recommended, but evidence in youth is limited and the dynamics of symptom change are poorly understood.Objectives: We investigated within-treatment changes in PTSD and substance use, and their temporal sequencing, in a randomised controlled tria
Background: Stereotactic body radiotherapy (SBRT) is an established treatment for previously unirradiated spinal metastases; however, the literature is limited with respect to SBRT as a re-irradiation salvage therapy. We performed a systematic review and meta-analysis as basis for joint ESTRO-ISRS clinical practice recommendations of salvage SBRT for spinal metastases. Methods: A systematic review
Herein, we present a case of severe immune-related adverse events (irAEs), myocarditis with myositis, and myasthenia gravis overlap syndrome (IM3OS) in a patient receiving an immune checkpoint inhibitor (ICI), as adjuvant therapy after surgery for muscle-invasive bladder cancer. An 80-year-old woman who had undergone a total cystectomy for bladder cancer presented with ptosis, diplopia, and paraly
