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Objectives Pseudomonas aeruginosa is a Gram-negative species that causes chronic and acute infections of the lung, skin, urinary tract and eyes. Most P. aeruginosa isolates are highly resistant to antibiotics and difficult to eradicate due to biofilm formation. The bacterium is known to utilize host proteins by diverse strategies in order to enhance its virulence. Vitronectin is a glycoprotein tha
The deuteron elastic structure function A(Q2) has been extracted in the range 0.7≤Q2≤6.0(GeV/c)2 from cross section measurements of elastic electron-deuteron scattering in coincidence using the Hall A Facility of Jefferson Laboratory. The data are compared to theoretical models, based on the impulse approximation with the inclusion of meson-exchange currents, and to predictions of quark dimensiona
This paper aims to portray the increasingly complex normative structure of international climate change regime, which consists of the 1992 UN Framework Convention on Cimate Change, the 1997 Kyoto Protocol as well as other additional elements that playing a role, such as the practices of the Intergovernmental Panel on Climate Change and the Global Environmental Facility and procedures of these inst
□ Total hip arthroplasty (THA) registers are established in several countries to collect data aiming to improve the results after THA. Monitoring of adverse outcomes after THA has focused mainly on revision surgery, but patientreported outcomes have also been investigated. □ Several surgery-related factors influencing the survival of the THA have been thoroughly investigated and have changed clini
This thesis is composed of four papers, the first two show the attempts made to extend the Pythia event generator to simulate heavy-ion collision events. The other two papers show methods to improve the hadronization mechanism in the Pythia model for a bettter agreement with the experimental data of pp and heavy-ion collisions.Paper I introduces a new model named Angantyr for heavy-ion collision e
Rare Earth (RE) ion doped nanomaterials are promising candidates for a range of quantum technology applications. Among RE ions, the so-called Kramers' ions possess spin transitions in the GHz range at low magnetic fields, which allows for high-bandwidth multimode quantum storage, fast qubit operations as well as interfacing with superconducting circuits. They also present relevant optical transiti
This paper treats the problem of control signal saturation caused by feedforward control from measurable load disturbances. An efficient feedforward compensator will often give significant peaks in the control signal at fast changes in the load disturbance. These peaks may cause the control signal to reach a saturation limit. In the paper, it is shown that the anti-windup function may cause unnece
Aims: An observational nationwide all-comers prospective register study to analyse outcomes after coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) in unprotected left main coronary artery (LMCA) disease. Methods and results: All patients undergoing coronary angiography in Sweden are registered in the Swedish Web-system for Enhancement and Development of Evidence-b
COVID-19 was first identified in Wuhan City in December 2019 and spread throughout Hubei Province and other parts of China. After causing significant morbidity and mortality in China, by February 2020, it had spread to numerous other countries, infecting millions of people and causing a large number of deaths across the world. The COVID-19 pandemic put a burden on almost all areas of the world inc
Recent years have seen an explosion in social media in our everyday lives, and a corresponding increase in social media research in IS. As social media researchers, we are intrigued by the problem of virtuality and context in social media research, and how we might apply reflexive research principles to such settings. In social media, the absence of a setting's real physical boundaries (to a large
Facebook is a frequently used Computer Mediated Environment (CME) for students and others to build social connections, with identities and deposited self-expression. Its widespread use makes it appropriate for consideration as an educational tool; though one that does not yet have clear guidelines for use. Whether a social networking site can be used for educational objectives remains largely unex
This chapter addresses the organization known as the Satanic Reds, which was founded in the latter half of the 1990s by Tani Jantsang and Philip Marsh. The organization has been described as a ”virtual audience cult,” and even though it is clear that several people have contributed in shaping it, the organization has been especially influenced by its two founders. Jantsang and Marsh have spoken fo
Despite the plethora of information on (S)-selective amine transaminases, the (R)-selective ones are still not well-studied; only a few structures are known to date, and their substrate scope is limited, apart from a few stellar works in the field. Herein, the structure ofLuminiphilus syltensis(R)-selective amine transaminase is elucidated to facilitate engineering towards variants active on bulki
Aims: To evaluate the cost-effectiveness of bimekizumab, an inhibitor of IL-17F and IL-17A, against biologic and targeted synthetic disease-modifying antirheumatic drugs (DMARD) for psoriatic arthritis (PsA) from the Swedish healthcare system perspective. Materials and methods: A Markov model was developed to simulate the clinical pathway of biologic [b] DMARD-naïve or tumor necrosis factor inhibi
We present an up-to-date, comprehensive summary of the rates for all types of compact binary coalescence sources detectable by the initial and advanced versions of the ground-based gravitational-wave detectors LIGO and Virgo. Astrophysical estimates for compact-binary coalescence rates depend on a number of assumptions and unknown model parameters and are still uncertain. Themost confident among t
