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ADHD is a common neurodevelopmental disorder that is defined by a pattern of hyperactivity and/or inattention that negatively affects an individual’s ability to function in everyday life. There are a multitude of challenges in correctly diagnosing ADHD. Symptoms are primarily behavior based and there are not any good biomarkers that can be used to help clinicians to diagnose the disorder correctly
This thesis is inspired by the lack of academic discourse on human rights aspects of human space settlement. It builds on the ever-growing literature on colonizing Mars and the ongoing public debate on the benefits versus disadvantages thereof. Taking on a critical approach, this thesis opens up a conversation on power, universalism, and legitimacy within space exploration, questioning both the on
A prototype of a novel 10B-based neutron detector called the Multi-Grid detector has been constructed, tested and commissioned for the European Spallation Source (ESS). The detector is constructed after the specifications set by the CSPEC instrument at ESS and is therefore called the CSPEC Multi-Grid detector. The detector uses multiple layers of solid coating containing 10B4C on the edges of a vo
The median age for Swedish earth embankment dams is about 60 years. Due to its longevity, one of the major concerns is the internal erosion causing increased seepage through the dam, which ultimately may increases the risk for dam failure. To meet this challenge, there is a need for improved monitoring methods. This in turn requires sensors to be installed inside the earth embankment dams in order
The behaviour and fate of stem cells is governed by the material properties of their surrounding microenvironment. Hence emulating the extracellular matrix poses as an attractive target for tissue engineering endeavours to create a stem cell substrate. Currently, the knowledge of the material properties is mostly limited to the macroscopic level which considerably limits the understanding of tissu
Abstract Parkinson’s disease (PD) is characterized by selective loss of dopaminergic neurons and progressive accumulation of intracellular alpha synuclein protein aggregates known as Lewy bodies. Due to pathological links to both sporadic and inherited cases of PD, alpha synuclein (asyn) has become a focal point for study, although the exact mechanisms of its toxicity are not known. In contrast to
This thesis is focusing on the protection of fundamental human rights at work for third country migrant workers in the European Union, a region which attracts more and more migrant workers in recent years. The first Chapter introduces the background briefly, the methodology and the sources on which the research is conducted on and provides the scope and definition of the issues which are under dis
Asylum seekers and refugees are one of the most demonised and marginalised social groups in Europe. Ireland's current agenda for dealing with refugees and asylum seekers is inadequate. The government of Ireland is aware of the inadequacy of response and has proposed to make a number of changes that will improve the standard of living for those who chose to apply for inclusion in Ireland. Howev
A need for autonomous electro-mechanical machines performing tasks that can save human efforts and even be deployed in hazardous environments along with the research in the field of human mind and body has led to new fields often called AI Robotics. To provide a mean for stimulating students and researchers around the world for promotion of this new field, an annual world championship, Robocup, ha
Som en effekt av den globala strävan som syftar till att motverka klimatförändringar som tillskrivs ökande koldioxidnivåer i atmosfären försöker man hitta okonventionella sätt att minska koldioxidutsläpp. CCS anses vara en metod med stor potential för detta syfte vilket har föranlett en världsomspännande prospektering av platser som kan användas för geologiskt lagring av koldioxid. Detta arbete As a part of a global attempt to mitigate impending climate change owing to increasing atmospheric CO₂levels unconventional methods which may reduce CO₂ emissions are extensively researched. Carbon Capture and Storage,(CCS) is considered to be a promising method for this purpose. As a consequence, worldwide prospection of geological sites in which CO₂ may be stored is currently underway. This th
The mass production of plug-in electric vehicles (PEVs) is expected to start in the coming years. Climate change, peak oil and the automotive and economic crisis have put a significant pressure on the current transportation regime. Increasing urbanisation, range and efficiency advantages of PEVs in city traffic and the problem of urban air pollution have moved cities into the focus of PEV dissemin
Cardiac thromboembolism attributed to atrial fibrillation (AF) is responsible for up to one-third of ischemic strokes. Stroke may be the first manifestation of previously undetected AF. Given the efficacy of oral anticoagulants in preventing AF-related ischemic strokes, strategies of searching for AF after a stroke using ECG monitoring followed by oral anticoagulation (OAC) treatment have been pro
BackgroundGenesis of acquired epilepsy includes transformations spanning genetic-to- network-level modifications, disrupting the regional excitatory/inhibitory balance. Methodology concurrently tracking changes at multiple levels is lacking. Here, viral vectors are used to differentially express two opsin proteins in neuronal populations within dentate gyrus (DG) of hippocampus. When activated, th
This article presents the methodological requirements for clinical examination and patient-reported outcomes measurements. The assessment of any measurement for clinical research in hand surgery is difficult. A method of measuring a criterion could be 100% reliable but 100% invalid. Bias may be present in our assessment if we do not take into account the methodological requirements related to reli
The cover and management factor (C) of the Universal Soil Loss Equation (USLE) is difficult to be estimated over broad geographic areas where meteorology and soil erosion are poorly monitored. This paper presents a new approach to estimate C factor based on multi-temporal images of Landsat TM/ETM and a weather generator. The linear spectral unmixture algorithm was adopted to calculate the fraction
Standard Model events with prompt, isolated, same-charge high-pT leptons are rare, and therefore events with such final states provide a powerful signature towards new discoveries. This thesis presents two searches for doubly charged Higgs bosons decaying into same-charge lepton pairs using proton–proton collision data recorded by the ATLAS detector at the LHC. Observation of doubly charged Higgs
Den digitalisering som för närvarande äger rum inom hälso- och sjukvårdssektorn ställer både nya krav och öppnar för nya möjligheter för enskilda medborgare, vårdpersonal samt olika aktörer i samhället. I många av de e-hälsolösningar som utvecklas finns bakomliggande tankar om ökad egenmakt (empowerment) för patienten genom att denne skall få ökad kontroll över sin egen hälsa och den information sThe digitalization that currently is taking place in healthcare raises questions about how this development, with visions of more patient participation and patient empowerment, changes this sector and what role eHealth can play in these changes. The term civic health technologies (Invånartjänster) is used in Sweden to describe eHealth in the healthcare sector that is developed and deployed by the
The nature of today’s business demands that Business Analytics (BA) extends to an operational level to better support employees in their decision-making. This is noticeable from the constant requests for new reports and changes in old ones at different employee levels. As a result, BA specialists or other power-users in functional departments are “bombarded” by these requests, and it becomes more
