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Hairy cell leukemia is an uncommon hematologic malignancy characterized by pancytopenia and marked susceptibility to infection. Tremendous progress in the management of patients with this disease has resulted in high response rates and improved survival, yet relapse and an appropriate approach to retreatment present continuing areas for research. The disease and its effective treatment are associa

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This study describes the design of degenerate primers and their use for synthesis of full-length avian influenza A neuramindase (NA). Each reaction was performed using either two forward primers and one reverse primer, or one forward primer and one reverse primer. Both primer combinations had comparable amplification efficiencies for all NA subtypes (1-9). A total of 115 virus strains, including b

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Under an action research paradigm, this thesis project explores the business potential of an environmental strategy and assesses the formulation of such a strategy implemented by an automotive original equipment manufacturer. Because of the heterogeneous nature of a company’s approach to environmental issues due to inter alia managerial conducts and company culture, this article provides an in-dep

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Musculoskeletal disorders (MSDs) affect muscles, joints, tendons and other supporting tissue. They are associated with pain and reduction in the normal range of activity. MSDs are amongst the most common causes of ill health and sickness absence, giving rise to substantial costs for the society. The key aim of this study is to calculate the economic costs of musculoskeletal disorders in Sweden rel

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Tiden då en bra produkt sålde sig själv är över. Forskare är överens om att det ökade utbudet av produkter i dagens samhälle har medfört att företagens utmaning numera ligger i att differentiera likartade produkter genom att förvandla dessa till ett koncept eller en livsstil. Värderingar och känslor som ett visst företag symboliserar har blivit viktiga element i denna differentiering. Varumärken ä

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The interaction of a solid target with an ultra-high intensity laser pulse can result in the laser plasma acceleration of ions. The recent proposal of a new laser plasma ion acceleration scheme, named chirped standing wave acceleration, has created interest in a new class of ultra-thin solid target materials, either freestanding or as a part of novel compound targets. In this thesis, it is assesse

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Väpnade konflikter är komplexa och mångfacetterade – män och kvinnors roller och nivå av inblandning varier avsevärt. Med detta i åtanke är det nödvändigt för internationell rätt och dess utövare att erbjuda ett reellt skydd, där ansvarsutkrävande och upprättelse erbjuds på lika villkor för alla oavsett kön. Risken är annars att vissa grupper osynliggörs. Sammanfattningsvis krävs det en nyanserad

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En två-kolonn MCSGP process för upprening av Liraglutid genomfördes i laboratorieskala. Den här processen är inte en kommersiell uppreningsprocess, utan att den är ett modellsystem med en realistisk peptidblandning och med en icke-kommersiell harts. Först modellerades processen med en konvektiv dispersiv modell för att beskriva koncentrationen genom kolonnen och den steriska massaktionsmodellen föA twin-column MCSGP process for the purification of Liraglutide was implemented at lab scale. This process is not a commercial separation step, but it is a model system with a realistic peptide mixture and with a non-commercial resin. First, the process was modeled using a convective dispersive model to describe the concentration along the column and the steric mass action model to describe the ad

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This study explores an approach for adapting the bundle of capillary tubes soil model for vertical soil solute transport modelling. The soil is split into thin layers allowing vertical water flow between capillaries of differing width with concomitant advective flow of solutes. Diffusion is included to improve realism. Modelling software is developed to apply the proposed adaption. Case studies ar

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The U.S. decision to partner with the Kurdish militia YPG to combat ISIS in Syria has caused its longstanding ally Turkey to align with Russia and Iran, and risks doing permanent damage to the NATO-alliance, ostensibly to the detriment of U.S. national interests. Taken at face value, this seems to contradict standard notions in neo-realist theory about state behavior. Given this seeming paradox, a

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Vi lever idag i vad som enkelt kan liknas vid ett uppkopplat copycat samhälle. Aldrig förut har saker varit så tillgängliga för oss och aldrig förut har saker blivit kopierade i den takt de blir idag. Ordet copy har blivit ersatt av ordet dupe och kopiorna framstår ha kommit in i finrummet. Fast Fashion företag som Zara, Primark och H&M kopierar de stora modehusen såväl som mindre designers. SToday’s society can easily be described as a connected copy-cat society. Never before have things been as accessible as they are today and never before have things been copied at the pace they are being copied today. The word copy have been replaced by the word dupe and dupes as such appears to have become a widely accepted phenomena within the fashion industry. Fast-fashion companies like Zara, P

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I takt med att den digitala arbetsmiljön växer måste kraven på användbarhet och tillgänglighet tillgodoses. Detta projekt genomfördes i samarbete med Assa Abloy Entrance Systems som är en global leverantör av automatiska entrélösningar. Projektets syfte var att utvärdera och utveckla användarupplevelsen och användbarheten av ett försäljningsverktyg genom att kartlägga och förstå användarna och derAs the digital work environment is growing, the demands of usability and accessibility must be met with increasingly higher standards. This project was performed in collaboration with Assa Abloy Entrance Systems, a global provider of automatic entrances. The project purpose was to evaluate and develop the user experience and usability of a sales tool by mapping and understanding the users and thei

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The foreign exchange (FX) market is today the world’s broadest, most active, financial market. One of many technical analysis techniques amongst professional FX traders, trying to narrow down the best entry and exit points in this market, is to utilize pivot points. The ability of this technique has, as far as we know, never been rigorously evaluated. In collaboration with the Malmö-based hedge fu

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The emerging green bond market is a novel research area with only a few studies being published in recent years. The increase in interest from issuers, investors, and academia shows the clear need for further investigation of the pricing dynamics affecting the green bond market. This study finds its theoretical foundation in the capital asset pricing model (CAPM), aiming to establish whether inves

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This thesis set out to continue the development of a short-wave infrared (SWIR) optical parametric amplifier (OPA). The system is based on a Yb-ber chirped pulse amplification (CPA) laser delivering 400 fs long pulses, centered around 1030 nm, at 200 kHz repetition rate and 40 W average power. The thesis focuses on pulse characterization, through use of frequency-resolved optical gating (FROG), of

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Vulnerability to climate change and the capacity to adapt to it are the result of intersecting power structures, system dynamics, and social identity markers otherwise known as intersectionality; and thus, differ greatly between contexts. However, despite the stark contextual differences between small and metropolitan cities, and lower and higher income countries, the policy and study of climate c

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This paper analyses how China’s growing taste for beef due to rising incomes, urbanization and preference for higher quality meat shaping Kazakhstan’s inefficient beef industry, and how Kazakhstan’s government is attempting to make it more efficient. The analysis done through qualitative methods by looking into the data from primary and secondary sources.

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We consider simple approximations of variances and covariances for order statistics from the standard extreme value distribution. Exact values and simulation results of the variances and covariances for certain sample sizes are used to determine the validity of the suggested approximations.

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Background: The relationship between Helicobacter pylori infection and pancreatic cancer has been investigated in three previous studies with contradictory results. The aim of the present study was to investigate the association between H. pylori seropositivity and the risk for pancreatic cancer in a nested case-control study within a population based cohort. Methods: Selected birth- year cohorts